Metaphor comprehension in Alzheimer's disease: novelty matters

The comprehension of non-literal language was investigated in 20 probable Alzheimer's disease (pAD) patients by comparing their performance to that of 20 matched control subjects. pAD patients were unimpaired in the comprehension of conventional metaphors and idioms. However, their performance was significantly lower in the case of non-conventional (novel) metaphor comprehension. This ability was not related to global cognitive deterioration or to deficits in the cognitive domains of attention, memory and language comprehension. On the other hand, the impairment in verbal reasoning appeared to be relevant for both novel and conventional metaphor comprehension. The relationship between novel metaphor comprehension and performance in the visual-spatial planning task of the Behavioral Assessment of the Dysexecutive Syndrome (BADS) suggests that executive impairment, possibly related to prefrontal dysfunction, may be responsible for the pAD patients' poor performance in novel metaphor comprehension. The present findings suggest a role of the prefrontal cortex in novel metaphor comprehension.     

On the “absoluteness” of category and magnitude scales of pain

The concept of “absolute scaling” (Zwislocki & Goodman, 1980) implies that direct judgments of sensory magnitude not only reflect the relative positions of the stimuli being judged, but also permit us to assess level differences in sensation. In order to explore this notion for different scaling methods, in the present investigation we compared magnitude estimation with category partitioning, a verbally anchored categorization procedure, in scaling painful pressure stimuli covering different intensity ranges. The results indicate that when the same stimulus range was presented after 1 week, both methods appeared to be highly reliable, with category partitioning faring somewhat better than magnitude estimation. When the stimulus range was unobtrusively changed between sessions, both methods reflected the within-subjects shift in absolute level. When two different sets of subjects judged the slightly different stimulus ranges, both methods resulted in scale values consistent with absolute scaling, though only category partitioning was sensitive enough to differentiate the two stimulus ranges. The results are discussed in the context of different possibilities of anchoring direct scaling methods in order to obtain “absolute” level information.     

When remembering causes forgetting: retrieval-induced forgetting as recovery failure

Retrieval practice on a subset of previously learned material can cause forgetting of the unpracticed material and make it inaccessible to consciousness. Such inaccessibility may arise because the material is no longer sampled from the set of to-be-recalled items, or, though sampled, its representation is not complete enough to be recovered into consciousness. In 2 experiments, it was examined whether retrieval-induced forgetting reflects a sampling or recovery failure by studying the time course of cued recall in this type of situation. Although retrieval practice reduced recall totals of the unpracticed items, in both experiments, the forgetting was not accompanied by an effect on the items' response latencies. This pattern of results is consistent with the view that inhibited items are successfully sampled but, because of a reduction in their activation level, do not exceed the recovery threshold.     

Exemplarization: a solution to the problem of consciousness?

In recent publications, Keith Lehrer developed the intriguing idea of a special mental process??exemplarization??and applied it in a sophisticated manner to different phenomena such as intentionality, representation of the self, the knowledge of ineffable content (of art works) and the problem of phenomenal consciousness. In this paper I am primarily concerned with the latter issue. The target of this paper is to analyze whether exemplarization, besides explaining epistemic phenomena such as immediate and ineffable knowledge of experiences, can also solve the ontological problem of consciousness. In particular, Lehrer suggests that if we consider exemplarization, zombies cannot provide an argument for anti-physicalism. I argue that exemplarization offers neither a physicalist explanation of the conceivability of zombies nor an elucidating physicalist account of their impossibility. Therefore, exemplarization cannot offer a physicalist solution to the ??hard problem?? of consciousness.     

Impulse control disorders in obese patients

The aim of this study was to determine the prevalence of impulse control disorders (ICDs) in morbidly obese individuals. One hundred bariatric surgery candidates were examined using a module of the Structured Clinical Interview for DSM-IV that has been developed for ICDs. Nineteen per cent suffered from at least one current ICD and 27% met the criteria for any lifetime ICD, most frequently skin picking (current, 8%; lifetime, 9%), compulsive buying (current 6%, lifetime 8%), and intermittent explosive disorder (current, 5%; lifetime, 10%). Patients with regular binge eating (N?=?25) reported significantly more often a history of at least one ICD compared with those without binge eating. The results indicate a high prevalence of ICDs among morbidly obese prebariatric surgery patients that are related to regular binge eating.     

Emotional support and counselling for people with visual impairment: Quantitative findings from a mixed methods pilot study

Aims: This paper reports on mainly quantitative findings from a mixed methods evaluation of a new model of emotional support and counselling for people with moderate visual impairment. Method: The CORE Outcome Measure was completed with service users at baseline and post‐intervention to assess the impact of the new service on psychological wellbeing and social functioning. Their perceived needs and expectations of the service were also explored. Results: Of the 35 individuals providing data at each assessment time, mean item scores on the CORE fell significantly (p<.001), taking the sample from within a clinical population before therapy, to a mean score below this following therapy. A more positive outlook accompanied this improvement in functioning. Discussion: Findings from the study augment the growing evidence that emotional support and counselling services can play an important role alongside and within related vision services. Implications for practice: The study indicates that therapeutic input for the visually impaired client group may need to target both wellbeing (feelings about oneself and the future) and problems (depression, anxiety, physical health, and trauma). Conclusions: Our findings suggest that a dual model of emotional support and counselling offers considerable benefit for people with visual impairment.     

Estimation of Health-State Utility Values and Factors Driving Health-Related Quality of Life in People Living with HIV and AIDS and Receiving cART in Germany: Baseline Analysis of a Cohort Study

Applied Research in Quality of Life - HIV has become a chronic disease since widespread of combined antiretroviral therapy (cART). Understanding the influence of therapeutic and preventive...     

“Like a Fanciful Kind of Half Being”: Mary Wollstonecraft's Criticism of Jean‐Jacques Rousseau

The article investigates the philosophical foundations and details of Mary Wollstonecraft's criticism of Jean‐Jacques Rousseau's views on the education and nature of women. I argue that Wollstonecraft's criticism must not be understood as a constructionist critique of biological reductionism. The first section analyzes the differences between Wollstonecraft's and Rousseau's views on the possibility of a true civilization and shows how these differences connect to their respective conceptions of moral psychology. The section shows that Wollstonecraft's disagreement with Rousseau's views on women was rooted in a broad scope of philosophical disagreement. The second section focuses on Rousseau's concept of nature, and I argue that Rousseau was neither a biological determinist nor a functionalist who denied that nature had any normative significance. The section ends with a discussion of Wollstonecraft's criticism of Rousseau's application of the distinction between the natural and the artificial. The third section focuses on Wollstonecraft's critique of Rousseau's claim that there are different standards for the perfectibility of men and women. The article concludes with a critical discussion of the claim that Aristotle would have provided Wollstonecraft with the philosophical tools she needed for her criticism of Rousseau.     

The Bergen left–right discrimination test: practice effects,reliable change indices,and strategic performance in the standard and alternate form with inverted stimuli

Several authors pointed out that left–right discrimination (LRD) tasks may be entangled with differential demands on mental rotation (MR). However, studies considering this interrelationship are rare. To differentially assess LRD of stimuli with varying additional demands on MR, we constructed and evaluated an extended version of the Bergen right–left discrimination (BRLD) test including additional subtests with inverted stickmen stimuli in 174 healthy participants (50♂, 124♀) and measured subjective reports on participants’ strategies to accomplish the task. Moreover, we analyzed practice effects and reliable change indices (RCIs) on BRLD performance, as well as gender differences. Performance significantly differed between subtests with high and low demands on MR with best scores on subtests with low demands on MR. Participants’ subjective strategies corroborate these results: MR was most frequently reported for subtests with highest MR demands (and lowest test performance). Pronounced practice effects were observed for all subtests. Sex differences were not observed. We conclude that our extended version of the BRLD allows for the differentiation between LRD with high and low demands on MR abilities. The type of stimulus materials is likely to be critical for the differential assessment of MR and LRD. Moreover, RCIs provide a basis for the clinical application of the BRLD.