One-minute time interval estimation as a novel potent indicator of emotional concerns in cancer patients prior to starting chemotherapy

Our study explored the potential relationship between time estimation and issues that lead to distress in cancer patients prior to starting chemotherapy. Time estimation was assessed in 375 chemonaïve patients with solid tumors by evaluating each subject’s prospective estimation of how quickly one minute passed compared to the actual time. The median estimated value (40 s) was used to stratify the patients into the two categories of fast and slow time estimation. The National Comprehensive Cancer Network Distress Thermometer (DT) and Problem List (PL) were used at the beginning of treatment to evaluate levels of distress and patient concerns. A fast time estimation correlated significantly with gender and items reported in the emotional domain on the PL. Females exhibited significantly faster time estimation than males. Patients who reported fear, worry and loss of interest in usual activities estimated the one-minute interval significantly faster than patients who did not report such items. In the multivariate logistic regression model, patients who experienced fast time estimation had a higher risk of reporting items in the emotional domain. Time estimation is a novel potent indicator of emotional concerns on the PL. This test is an easily performed, time-saving, nonintrusive, ultrashort screening tool that is suitable even for patients who are not willing to reveal their emotional status via direct questionnaires.

     

Blocked vs. interleaved presentation and proactive interference in episodic memory

Although a number of theoretical accounts of proactive interference (PI) in episodic memory have been proposed, existing empirical evidence does not support conclusively a single view yet. In two experiments we tested the predictions of the temporal discrimination theory of PI against alternative accounts by manipulating the presentation schedule of study materials (lists blocked by category vs. interleaved). In line with the temporal discrimination theory, we observed a clear buildup of (and release from) PI in the blocked condition, in which all the lists of the same category were presented sequentially. In the interleaved condition, with alternating lists of different categories, a more gradual and smoother buildup of PI was observed. When participants were left free to choose their presentation schedule, they spontaneously adopted an interleaved schedule, resulting again in more gradual PI. After longer delays, we observed recency effects at the list level in overall recall and, in the blocked condition, PI-related effects. The overall pattern of findings agrees with the predictions of the temporal discrimination theory of PI, complemented with categorical processing of list items, but not with alternative accounts, shedding light on the dynamics and underpinnings of PI under diverse presentation schedules and over different time scales.     

‘Journeys’ in the Life-Writing of Adult-Child Dementia Caregivers

This article explores how Alzheimer’s disease caregivers struggle under the impact of a parent’s memory loss on their own personality. In particular, it analyses how caregivers perceive and, thus, present their experiences of the ever intensifying caregiving activity in terms of a ‘journey’. In doing so, this work takes into account both the patient’s continuing bodily as well as cognitive decline and its intricately linked influence on the caregiver’s physical and emotional stability. Equally, this study investigates how caregivers portray memory loss, and how their portrayal fits into our conceptualisation of illness narratives and the culture of autobiographical writing.     

Prior probabilities and representational momentum

In many previous experiments on representational momentum (in which memory for the final location of a moving target is displaced in the direction of target motion), participants judged whether a probe presented after a target vanished was at the same location where that target vanished or at a different location. The experiments reported here manipulated the actual or expected prior probability a same response to such a probe would be correct. In Experiment 1, a same response was correct on 10%, 30%, 50%, 70%, or 90% of the trials, but observers were not instructed regarding these probabilities. In Experiment 2, a same response was correct on 11% of the trials, but different groups of participants were instructed that a same response would be correct on 10%, 30%, 50%, 70%, or 90% of the trials. Probabilities of a same response to different probe positions, weighted mean estimates of representational momentum, hit rates and false alarm rates, and d′ and ß are reported. Representational momentum occurred in all conditions but was not influenced by actual or expected prior probability a same response would be correct. The data suggest representational momentum does not result from changes in sensitivity, and a distinction between performance bias and competence bias is introduced.     

Lateralized suckling in domestic horses (Equus caballus)

Brain lateralization enables preferential processing of certain stimuli and more effective utilization of these stimuli in either the left or the right cerebral hemisphere. Horses show both motor and sensory lateralization patterns. Our aim was to determine whether a lateralized response could be detected in foals during the naturally side-biased behaviour, suckling. The foals’ preferred suckling side could be the effect of either visual or motor lateralization. In the case of a visual lateralized response, foals are expected to suck more often from the mother’s right side, so potential danger can be detected by the better adapted right hemisphere (i.e. left eye). Motor lateralization can be identified when a foal will suck predominantly from one side, either left or right. We found no population trend in the preferred suckling side, but we detected significant differences amongst individual foals. One-third (35.4 %) of 79 foals showed a strong, either right or left side preference which increased with age. The mothers did not influence the foals’ suckling side preferences either by side-biased rejection or termination of suckling. According to our findings, a general pattern of sucking with the left eye open for better danger detection and recognition is unlikely in foals up to 7 months old. Foals of this age are probably young or fully focused on suckling and rely on their mothers’ vigilance. Individual side preferences amongst foals are suggested to be based on motor lateralization.     

Two (or three) is one too many: testing the flexibility of contextual cueing with multiple target locations

Visual search for a target object is facilitated when the object is repeatedly presented within an invariant context of surrounding items ("contextual cueing"; Chun & Jiang, Cognitive Psychology, 36, 28-71, 1998). The present study investigated whether such invariant contexts can cue more than one target location. In a series of three experiments, we showed that contextual cueing is significantly reduced when invariant contexts are paired with two rather than one possible target location, whereas no contextual cueing occurs with three distinct target locations. Closer data inspection revealed that one "dominant" target always exhibited substantially more contextual cueing than did the other, "minor" target(s), which caused negative contextual-cueing effects. However, minor targets could benefit from the invariant context when they were spatially close to the dominant target. In sum, our experiments suggest that contextual cueing can guide visual attention to a spatially limited region of the display, only enhancing the detection of targets presented inside that region.     

Zwischen transzendentaler Genese und faktischer Existenz. Konfigurationen des Lebensbegriffs bei Natorp, Husserl und Heidegger

Die vorliegende Studie befasst sich mit der Deutung, die der so vielschichtige Begriff des Lebens Anfang des 20. Jahrhunderts in der neukantianischen Transzendentalphilosophie sowie in der Ph?nomenologie erfahren hat. Am Beispiel von Natorp, Husserl und Heidegger werden verschiedene Ans?tze analysiert, die darauf abzielen, den Lebensbegriff aus seinen vitalistischen und historistischen Verengungen zu befreien und zur Deutung der Grundstrukturen des Bewusstseins bzw. der faktischen Existenz heranzuziehen. Dabei zeichnet sich eine Entwicklung ab, die von einer wenig differenzierten Verwendung des Lebensbegriffs als Synonym der Bewusstseinsdynamik als solcher (Natorp) über die Dualit?t von vorph?nomenologischem Welterleben und transzendentalem Bewusstseinsleben (Husserl) bis hin zur Einsicht in die vorsubjektive Primordialit?t des „Lebens selbst“ (Heidegger) führt. Das Leben erscheint somit letztlich als kein wie immer geartetes Was, sondern als ein Wie, n?mlich als die M?glichkeit, das Kontinuum des Welterlebens jederzeit zu durchbrechen und es auf den Grad seiner N?he zur Intensit?t des Ursprungserlebens hin transparent zu machen.     

Representing others' actions: the role of expertise in the aging mind

A large body of evidence suggests that action execution and action observation share a common representational domain. To date, little is known about age-related changes in these action representations that are assumed to support various abilities such as the prediction of observed actions. The purpose of the present study was to investigate (a) how age affects the ability to predict the time course of observed actions; and (b) whether and to what extent sensorimotor expertise attenuates age-related declines in prediction performance. In a first experiment, older adults predicted the time course of familiar everyday actions less precisely than younger adults. In a second experiment, younger and older figure skating experts as well as age-matched novices were asked to predict the time course of figure skating elements and simple movement exercises. Both young age and sensorimotor expertise had a positive influence on prediction performance of figure skating elements. The expertise-related benefit did not show a transfer to movement exercises. Together, the results suggest a specific decline of action representations in the aging mind. However, extensive sensorimotor experience seems to enable experts to represent actions from their domain of expertise more precisely even in older age.