Personhood and neuroscience: naturalizing or nihilating?

Personhood is a foundational concept in ethics, yet defining criteria have been elusive. In this article we summarize attempts to define personhood in psychological and neurological terms and conclude that none manage to be both specific and non-arbitrary. We propose that this is because the concept does not correspond to any real category of objects in the world. Rather, it is the product of an evolved brain system that develops innately and projects itself automatically and irrepressibly onto the world whenever triggered by stimulus features such as a human-like face, body, or contingent patterns of behavior. We review the evidence for the existence of an autonomous person network in the brain and discuss its implications for the field of ethics and for the implicit morality of everyday behavior.     

The influence of sad mood on cognition

Neuroimaging has identified an overlapping network of brain regions whose activity is modulated by mood and cognition. Studies of depressed individuals have shown changes in perception, attention, memory, and executive functions. This suggests that mood has a pervasive effect on cognition. Direct evidence of the effect of sad mood on cognition is surprisingly limited, however. Published studies have generally addressed a single cognitive ability per study because the fleeting nature of laboratory-induced mood precludes extended testing, and robust findings are limited to mood effects on memory for emotional stimuli. In this study, sad mood was induced and prolonged, enabling the effects of mood to be assessed for an array of abilities, including those that share neural substrates with sad mood and those affected by depression. Sad mood affected memory for emotional words and facial emotion recognition, but not the other processes measured, with a significant nonuniformity of effect over tasks. These results are consistent with circumscribed effects of sad mood on certain emotion-related cognitive processes, but not on cognition more generally.     

Effects of a School‐Based Life Skills and HIV‐Prevention Program for Adolescents in Mexican High Schools1

A school‐based life skills and sexuality education HIV/AIDS program for adolescents was evaluated in Toluca, Mexico, through a quasi‐experimental pre–post design with 1,566 cases, divided over a control group and an experimental group. Based on a previously tested path model, 3 levels of variables were included as a guide for the contents of the program: personal variables (self‐knowledge, self‐efficacy regarding condom use, and decision making), intervening variables (subjective norms about, knowledge about HIV/AIDS, and attitudes toward condoms), and outcome variables (communication on sexuality and intentions to use condoms). Evaluation was conducted following these categories. Significant increases in all of these variables recognized as precursors of safer sex were found in the experimental group.     

Orientation Invariance and Geometric Primitives in Shape Recognition

Although it is generally assumed that vision is orientation invariant, that is, that shapes can be recognized regardless of viewing angle, there is little evidence that speaks directly to this issue, and what evidence there is fails to support orientation invariance. We propose an explanation for the previous results in terms of the kinds of shape primitives used by the visual system in achieving orientation invariance: Whereas contours are used at stages of vision that ore not orientation invariant, surfaces and/or volumes are used at stages of vision that are orientation invariant. The stimuli in previously reported studies were wire forms, which can represented only in terms of contour. In four experiments, testing both short-term and long-term memory for shape, we replicated the previous failures of orientation invariance using wire forms, but found relatively good or perfect orientation invariance with equivalently shaped surfaces.     

Illness perception in people with chronic obstructive pulmonary disease

Illness perception (IP) concerns how patients evaluate living with a disease. To get a broader understanding of IP in patients with chronic obstructive pulmonary disease (COPD), we investigated whether breathlessness is an important precursor of IP and whether IP in its turn is related to mental health, physical health and global quality of life (QOL). One hundred and fifty‐four patients with COPD participated in a cross‐sectional survey. Participants underwent pulmonary function testing, provided socio‐demographic and clinical information, and completed the following standardized instruments: Brief Illness Perception Questionnaire, Respiratory Quality of Life Questionnaire, Short‐Form 12 Health Survey and the Quality of Life Scale. Multiple regression analyses were performed. A high IP score indicates that a patient believes that his/her illness represents a threat. Participants with a high score on the IP dimensions consequences, identity, concern and emotional representation, experienced more breathlessness. High scores on the IP dimensions consequences, identity and concern were associated with impaired physical health and high scores on the IP dimensions consequences, identity and emotional representation were associated with impaired mental health. Impaired global QOL was associated with high scores on the IP dimensions consequences, identity, concern, coherence and emotional representation. The strength of the associations between breathlessness and physical/mental health and global QOL decreased when certain dimensions of IP were included as predictors, indicating that IP to some extent acts as a mediating factor. These findings may have practical implications of patient counselling by helping COPD patients to cope with their disease by restructuring their personal models of illness.     

Whiteness and Disability: Double Marginalization

Whiteness involves a set of privileges that are lost or removed when a person becomes, or is perceived to be, disabled. For European American women, disability impacts femininity, the part of identity that differentiates them from European American men who hold maximal power and privilege in U.S. society. Disability represents a health issue, a barrier to social participation, and vulnerability to individual and societal abuse. Development of a healthy disability identity allows European American women to negotiate the multicultural situation of being White, women, and disabled.     

Effect of socioeconomic status (SES) disparity on neural development in female African‐American infants at age 1 month

There is increasing interest in both the cumulative and long‐term impact of early life adversity on brain structure and function, especially as the brain is both highly vulnerable and highly adaptive during childhood. Relationships between SES and neural development have been shown in children older than age 2 years. Less is known regarding the impact of SES on neural development in children before age 2. This paper examines the effect of SES, indexed by income‐to‐needs (ITN) and maternal education, on cortical gray, deep gray, and white matter volumes in term, healthy, appropriate for gestational age, African‐American, female infants. At 5 weeks postnatal age, unsedated infants underwent MRI (3.0T Siemens Verio scanner, 32‐channel head coil). Images were segmented based on a locally constructed template. Utilizing hierarchical linear regression, SES effects on MRI volumes were examined. In this cohort of healthy African‐American female infants of varying SES, lower SES was associated with smaller cortical gray and deep gray matter volumes. These SES effects on neural outcome at such a young age build on similar studies of older children, suggesting that the biological embedding of adversity may occur very early in development.