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81.
Many, but not all, young children with high levels of fearful inhibition will develop internalizing problems. Individual studies have examined either child regulatory or environmental factors that might influence the level of risk. We focused on the interaction of regulation and environment by assessing how early fearful inhibition at age 2, along with inhibitory control and maternal negative behaviors at age 3, interactively predicted internalizing problems at age 6. A total of 218 children (105 boys, 113 girls) and their mothers participated in the study. Results indicated a three-way interaction among fearful inhibition, inhibitory control, and maternal negative behaviors. The correlation between fearful inhibition and internalizing was significant only when children had low inhibitory control and experienced high levels of maternal negative behaviors. Either having high inhibitory control or experiencing low maternal negative behaviors buffered against the adverse effect caused by the absence of the other. These findings highlight the importance of considering associations among both within-child factors and environmental factors in studying children’s socioemotional outcomes. 相似文献
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Daniel A. Hackman Robert Gallop Gary W. Evans Martha J. Farah 《Developmental science》2015,18(5):686-702
Childhood socioeconomic status (SES) predicts executive function (EF), but fundamental aspects of this relation remain unknown: the developmental course of the SES disparity, its continued sensitivity to SES changes during that course, and the features of childhood experience responsible for the SES–EF relation. Regarding course, early disparities would be expected to grow during development if caused by accumulating stressors at a given constant level of SES. Alternatively, they would narrow if schooling partly compensates for the effects of earlier deprivation, allowing lower‐SES children to ‘catch up’. The potential for later childhood SES change to affect EF is also unknown. Regarding mediating factors, previous analyses produced mixed answers, possibly due to correlation amongst candidate mediators. We address these issues with measures of SES, working memory and planning, along with multiple candidate mediators, from the NICHD Study of Early Childcare (n = 1009). Early family income‐to‐needs and maternal education predicted planning by first grade, and income‐to‐needs predicted working memory performance at 54 months. Effects of early SES remained consistent through middle childhood, indicating that the relation between early indicators of SES and EF emerges in childhood and persists without narrowing or widening across early and middle childhood. Changes in family income‐to‐needs were associated with significant changes in planning and trend‐level changes in working memory. Mediation analyses supported the role of early childhood home characteristics in explaining the association between SES and EF, while early childhood maternal sensitivity was specifically implicated in the association between maternal education and planning. Early emerging and persistent SES‐related differences in EF, partially explained by characteristics of the home and family environment, are thus a potential source of socioeconomic disparities in achievement and health across development. 相似文献
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Bishop SJ Cohen JD Fossella J Casey BJ Farah MJ 《Cognitive, affective & behavioral neuroscience》2006,6(1):62-70
Early studies of genetic effects on brain activity have been conducted to investigate primarily either the influence of polymorphisms
in dopaminergic genes, especially the catechol-O-methyltransferase (COMT) gene, on prefrontal cognitive processes such as working memory, or that of polymorphisms in the
serotonin transporter gene on the amygdala response to threatening stimuli. Here, we address genetic influences on the neural
systems underlying cognitive-affective interactions. Specifically, we assess the effect of the COMT val158met polymorphism on frontal regulation of attention under emotional distraction. Healthy volunteers were scanned while performing
a house-matching task with affectively negative versus neutral distractors. Effects of val allele load were examined on frontal
regions associated with attentional control and emotion regulation, and on parahippocampal regions associated with perception
of houses. As we predicted, val load correlated positively with activity in control- and task-related regions during performance
under emotional distraction. These findings provide an initial step toward identifying genetic contributions to interindividual
variability in recruitment of mechanisms that regulate affective processing. 相似文献
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The cerebral regulation of cardiovascular functioning varies along both a lateral and a longitudinal axis. The parasympathetic and sympathetic nervous systems are lateralized to the left and right cerebral hemispheres, respectively. Further, the frontal lobes are known to be inhibitory in nature, whereas the temporal lobes are excitatory. However, no systematic investigation has been conducted to determine the nature and strength of the relationship between the left and right frontal and temporal lobes in regulating cardiovascular activity. The present investigation sought to examine these relationships by testing the hypothesis that negative correlations would be found between baseline heart rate and blood pressure and asymmetry of alpha magnitude across the frontal lobes. Further, positive correlations were hypothesized to exist across the temporal lobes. A total of 20 women were asked to relax with their eyes closed while heart rate and blood pressure as well as quantitative electroencephalography data were obtained. The results indicated that, as hypothesized, significant negative correlations existed across the frontal lobes and significant positive correlations existed across the temporal lobes. The results provide further support for a division of responsibility between the left and right frontal and temporal lobes in the regulation of heart rate and blood pressure. 相似文献
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