Human Rights,Cultural Pluralism,and International Health Research

In the field of bioethics, scholars have begun to consider carefully the impact of structural issues on global population health, including socioeconomic and political factors influencing the disproportionate burden of disease throughout the world. Human rights and social justice are key considerations for both population health and biomedical research. In this paper, I will briefly explore approaches to human rights in bioethics and review guidelines for ethical conduct in international health research, focusing specifically on health research conducted in resource-poor settings. I will demonstrate the potential for addressing human rights considerations in international health research with special attention to the importance of collaborative partnerships, capacity building, and respect for cultural traditions. Strengthening professional knowledge about international research ethics increases awareness of ethical concerns associated with study design and informed consent among researchers working in resource-poor settings. But this is not enough. Technological and financial resources are also necessary to build capacity for local communities to ensure that research results are integrated into existing health systems. Problematic issues surrounding the application of ethical guidelines in resource-poor settings are embedded in social history, cultural context, and the global political economy. Resolving the moral complexities requires a commitment to engaged dialogue and action among investigators, funding agencies, policy makers, governmental institutions, and private industry.     

Lacking <Emphasis Type="Italic">lack</Emphasis>: a reply to Joldersma

First I would like to thank Clarence Joldersma for his review of our Poststructuralism, Philosophy, Pedagogy (Marshall, 2004-PPP). In particular, I would thank him for his opening sentence: “[t]his book is a response to a lack.” It is the notion of a lack, noted again later in his review, which I wish to take up mainly in this response. Rather than defending or elaborating our particular contributions to PPP—the latter would be a great indignity to my colleagues as I would not write over them—I will take the opportunity to develop the theme of a lack, as I believe that Joldersma has raised a very important issue. But first I will respond briefly to some of Joldersma’s general and opening statements about the book, and my philosophical position in particular.

Revisiting places passed: sensitization of exploratory activity in rats with hippocampal lesions

We examined the involvement of the hippocampus in short-term changes in exploratory behaviour in an open field (Experiment 1) and experimental contexts (Experiment 2). In Experiment 1, rats with excitotoxic lesions of the hippocampus were more likely to revisit recently visited zones within the open field than were control rats. Similarly, in Experiment 2 rats with hippocampal lesions showed greater exploration of a context that they had recently explored than a context that they had less recently explored. This short-term sensitization effect was not evident in control rats. These findings are consistent with the suggestion that the recent presentation of a stimulus has two opposing effects on behaviour, sensitization, and habituation, and that hippocampal lesions disrupt the short-term process responsible for habituation, but not that responsible for sensitization.     

Beyond Compliance: Mother–Child Joint Action During a “Do” Task

Much of the literature on parent-toddler interactions does not account for the lack of independence in data. This investigation used a theory and method appropriate for examining the moment-to-moment patterns of joint actions between mothers and toddlers during a “do” task. Using contextual action theory to guide a mixture of methods, we observed and described the joint goal-directed series of actions of mothers and their toddlers as well as mothers’ intentions, meanings, and emotions they ascribed to their actions. Additionally, the associations between the patterns of joint mother-toddler actions and children’s negative emotionality were examined. Thirty mothers and their children participated in the study. Data collection included video-recorded activity, video recall interviews, and self-report questionnaires. Quantitative and qualitative analysis of the data revealed that (a) children were mostly engaged in the task alongside with their mothers’ on-going involvement; (b) mothers attributed a range of meanings to their interactions with their children; and (c) mothers’ perceptions of their toddlers’ dimensions of emotional negativity were associated with the organization of dyads’ joint goal directed actions—both when children were engaged in the task or self-focused.     

An Analysis of Intrinsicality

The leading account of intrinsicality over the last thirty years has arguably been David Lewis's account in terms of perfect naturalness. Lewis's account, however, has three serious problems: i) it cannot allow necessarily coextensive properties to differ in whether they are intrinsic; ii) it falsely classifies non‐qualitative properties like being Obama as non‐intrinsic; and iii) it is incompatible with a number of metaphysical theories that posit irreducibly non‐categorical properties. I argue that, as a result of these problems, Lewis's account should be rejected and replaced with an alternative account, which also analyses intrinsicality in terms of perfect naturalness, but which avoids these problems.     

Effects of Weight Cue Reactivity on Self-Report Measures of Body Dissatisfaction

Research has shown that answers on self-report measures can be influenced by a participant’s awareness of information regarding the study (“reactivity”). There exists a gap in the literature regarding weight cue reactivity on self-report measures of body dissatisfaction (BD). This type of reactivity involves exposing participants to information regarding their height, weight, or body mass index (BMI). Ninety-Nine participants (45.5 % female, mean age = 20.17, SD = 3.08) were randomly assigned to one of three conditions: proximal weight cue (being weighed before completing measures); distal weight cue (knowledge of impending measurement following questionnaire completion); and no weight cues (control), all before measures of BD. Perceived body size and BD were measured using the Stunkard Figure Rating Scale. Two separate ANCOVAs revealed a significant main effect for condition on self-reported perceived body size F [2,92] = 5.22, p = 0.01, η2 = 0.10, as well as on BD, F [2,92] = 9.46, p < 0.001, η2 = 0.17, while controlling for BMI. Both proximal and distal cues elicited elevated BD; only proximal cues elicited self-reported perceived body size. These results quantify the impact of weight cue reactivity effects on self-report measures and suggest that researchers and/or clinicians collect answers on such measures prior to anthropometric data.     

Watching others in a positive state does not induce optimism bias in common marmosets (Callithrix jacchus), but leads to behaviour indicative of competition

Animal Cognition - Emotional contagion is suggested to facilitate group life by enhancing synchronized responses to the environment. Cooperative breeders are an example of a social system that...