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Waldman ID Nigg JT Gizer IR Park L Rappley MD Friderici K 《Cognitive, affective & behavioral neuroscience》2006,6(1):18-30
There is resurgent interest in the psychiatric literature in endophenotypes, variables thought to more strongly reflect the
effects of candidate genes than do manifest disorders. In a sample of 176 children with attention deficit hyperactivity disorder
(ADHD) and 52 of their siblings, we examined the validity of several putative endophenotypes for ADHD that represent commonly
used clinical measures of multiple cognitive/neuropsychological domains of executive functions (EFs). We review their distributional
normality, their relations to ADHD symptoms in probands and unaffected siblings relative to nonADHD controls, and their correlation
in siblings. We also tested the EF measures’ associations with the ADRA2A gene and whether they mediated or moderated the associations between ADHD and ADRA2A. Several EF measures showed association with ADRA2A, as well as moderation, but not mediation, of its association with ADHD. Implications of the results for evaluating the validity
and utility of putative endophenotype measures and for finding candidate gene effects on ADHD are discussed. 相似文献
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Acute alcohol intoxication effects on memory were examined using a recollection-based word recognition memory task and a repetition priming task of memory for the same information without explicit reference to the study context. Memory cues were equivalent across tasks; encoding was manipulated by varying the frequency of occurrence (FOC) of words in the study lists. Twenty-two female and male social drinkers (age 21-24 years) completed equivalent versions of the memory tasks in two counterbalanced sessions (alcohol challenge, no-alcohol). Alcohol and the FOC manipulation affected recollection-based memory processing, but not repetition priming. Results supported alcohol's dissociative effects on memory systems. 相似文献
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Marsha E. Boveja 《Journal of multicultural counseling and development》1998,26(2):110-119
The purpose of this study is to examine the relationship between perceived parenting styles and urban adolescents' learning and studying strategies. The results revealed that those adolescents who perceived their parents as being authoritative tended to engage in more effective learning and study strategies. Implications are discussed for counselors and teachers using this information as a fostering tool in their work with urban adolescents. 相似文献
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Grover J Whitehurst Marsha Ironsmith Michael goldfein 《Journal of experimental child psychology》1974,17(2):288-302
Six 4- to 5-yr-old subjects were exposed to five sessions in which an adult model used passive sentences to describe a set of modeling stimuli. Probe stimuli, which the subjects were asked to describe without benefit of modeling and without selective reinforcement were interspersed among modeling stimuli. A matched group of control subjects received probletrials but no modeling trials. Both groups of subjects were subsequently tested on their ability to comprehend active and passive sentence forms. Every subject in the experimental group produced passive sentences on probe trials even though there was considerable variability in the number of passives produced. No control subject produced passives. The modeling procedure increased the comprehension scores of the experimental group above those of the control group though the scores of both groups were above chance. The results were contrasted with earlier studies in which modeling was ineffective in producing passive usage and in which comprehension of the passive was not demonstrated by even older children. 相似文献
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William S. MacAllister Moshe Maiman Marsha Vasserman Taryn Fay-Mcclymont Brian L. Brooks Elisabeth M. S. Sherman 《Child neuropsychology》2019,25(7):992-1002
Despite its popularity in the neuropsychological evaluation of children, the utility of the Wechsler Intelligence Scale for Children – Fifth Edition (WISC-V) has not yet been investigated in children with epilepsy. Eighty clinically referred children and adolescents with epilepsy were administered the WISC-V as part of a comprehensive assessment and scores were compared to matched controls from the WISC-V standardization sample. T tests compared WISC-V indices and subtests between patients and controls and Chi-square analyses compared the rates of low scores. Correlational analyses assessed the relationships between epilepsy severity variables (e.g., age of onset, duration of epilepsy, number of antiepileptic drugs, seizure frequency). All WISC-V composites and subtests were significantly lower in patients versus controls and the rate of low scores was higher in patients than controls for all composites and subtests with the exception of Figure Weights. The Working Memory Index and Processing Speed Index were most sensitive to impairment, while the Verbal Comprehension Index and Fluid Reasoning Index were least sensitive. Of the epilepsy severity variables, age of seizure onset and number of antiepileptic drugs were strong predictors of deficits, whereas seizure frequency was the weakest predictor. Importantly, no significant differences were seen in children with right hemisphere epilepsy versus left on the five WISC-V composites, though a trend was seen towards a lower Visual-Spatial Index in those with right-sided focal seizures. 相似文献
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Donna S. Sheperis Komal Korani Marsha Milan‐Nichols Carl J. Sheperis 《Journal of counseling and development : JCD》2019,97(1):25-32
This quantitative Q‐sort research was designed to evaluate representations of counselor qualifications and to determine which configurations account for the variance in consumer preference and selection. The sample consisted of 161 graduate and undergraduate students in a regional university in Texas. An iterative inverse factor analysis produced 3 distinct factors that accounted for 65.85% of the variance in the data, explaining a majority of the differences in how consumers perceive counselor credentials. 相似文献