Shaw’s stored information as a quantitative measure of sequential structure

In this paper, we describe a method to study the sequential structure in interevent times. The technique uses the stored information of an iterative map developed by-Shaw (1984). The stored information is a quantitative measure of the sequential organization or predictability in data. This paper discusses the concept of stored information and provides a FORTRAN routineto compute the stored information of interevent time data. Several synthetic data sets with known sequential structures are examined. Finally, we present some initial results from computing the stored information of experimental interresponse time data.     

Application of chaos theory to biology and medicine

The application of “chaos theory” to the physical and chemical sciences has resolved some long-standing problems, such as how to calculate a turbulent event in fluid dynamics or how to quantify the pathway of a molecule during Brownian motion. Biology and medicine also have unresolved problems, such as how to predict the occurrence of lethal arrhythmias or epileptic seizures. The quantification of a chaotic system, such as the nervous system, can occur by calculating the correlation dimension (D2) of a sample of the data that the system generates. For biological systems, the point correlation dimension (PD2) has an advantage in that it does not presume stationarity of the data, as the D2 algorithm must, and thus can track the transient non-stationarities that occur when the systems changes state. Such non-stationarities arise during normal functioning (e.g., during an event-related potential) or in pathology (e.g., in epilepsy or cardiac arrhythmogenesis). When stochastic analyses, such as the standard deviation or power spectrum, are performed on the same data they often have a reduced sensitivity and specifity compared to the dimensional measures. For example, a reduced standard deviation of heartbeat intervals can predict increased mortality in a group of cardiac subjects, each of which has a reduced standard deviation, but it cannot specify which individuals will or will not manifest lethal arrhythmogenesis; in contrast, the PD2 of the very same data can specify which patients will manifest sudden death. The explanation for the greater sensitivity and specificity of the dimensional measures is that they aredeterministic, and thus are moreaccurate in quantifying the time-series. This accuracy appears to be significant in detecting pathology in biological systems, and thus the use of deterministic measures may lead to breakthroughs in the diagnosis and treatment of some medical disorders.     

Motion coherence and conjunction search: Implications for guided search theory

Feature integration theory has recently been revised with two proposals that visual conjunction search can be parallel under some circumstances—either because items with nontarget features are inhibited, or because items with target features are excited. We examined whether excitatory or inhibitory guidance controlled conjunction search for an X oscillating in one direction among Os oscillating in that direction and Xs oscillating in another. Search was affected by whether items oscillated in phase with each other, and it was exceptionally difficult when items with target motion moved out of phase with each otherand items with nontarget motion moved out of phase. The results suggest that conjunction search can be guided both by excitation of target features and by inhibition of nontarget features.     

Initial experiences with cognitive therapy of schizophrenic patients

Based on earlier experiences of various groups of authors, we developed and modified a programme of cognitive therapy for schizophrenic patients. The aim of the application of the therapeutic programme to subacute patients was to decrease subjectively perceptible basic disorders and to improve the functions of performance. The present results and experiences with 4 groups consisting of a total of 31 patients encourage us to continue applying cognitive procedures of therapy. Problems of the ascertainment of measuring values and fundamental questions of therapeutic efficacy are discussed.     

The architecture of complexity: A new blueprint

The logic of scientific discovery is now a concern of computer scientists, as well as philosophers. In the computational approach to inductive inference, theories are treated as algorithms (computer programs), and the goal is to find the simplest algorithm that can generate the given data. Both computer scientists and philosophers want a measure of simplicity, such that simple theories are more likely to be true than complex theories. I attempt to provide such a measure here. I define a measure of simplicity for directed graphs, inspired by Herbert Simon's work. Many structures, including algorithms, can be naturally modelled by directed graphs. Furthermore, I adapt an argument of Simon's to show that simple directed graphs are more stable and more resistant to damage than complex directed graphs. Thus we have a reason for pursuing simplicity, other than purely economical reasons.This paper is based on part of my doctoral dissertation. Thanks to my thesis supervisor Professor Alasdair Urquhart for his encouragement, constructive criticism, and for directing me to several relevant articles; to my advisor, Professor Ian Hacking, for reminding me to concentrate on results that might have some application in the real world; to Professor Eric Mendelsohn for checking my use of graph theory; and to my friend Wendy Brandts for sharing her ideas on a closely related problem.Thanks to my friends and family (the latter being a (proper) subset of the former, and both including Dr. Louise Linney, of course) for ongoing support in my scholastic endeavors.Thanks to the Social Sciences and Humanities Research Council for financial assistance. (Awards 452-86-5885 and 453-87-0513.) Thanks to the University of Toronto for financial assistance.     

Attention deficit disorder with hyperactivity and methylphenidate: The effects of dose and mastery level on children's learning performance

This investigation examined the relationship between methylphenidate (MPH) and the learning and recall of paired associations by children with attention deficit disorder with hyperactivity (ADDH). Forty-five children with ADDH were randomly assigned to one of three groups (novel, partial mastery, and mastery learning) that varied in the amount of previous learning of paired associations and participated in a double-blind, placebo-control, repeated-measures-across-dose (crossover) design. Each child received four doses of MPH (5 mg, 10 mg, 15 mg, and 20 mg) and a placebo in a random, counterbalanced sequence. The results indicated that both the rate of acquisition and accuracy in learning paired associations were significantly, but differentially, affected by MPH dose and the degree of learning mastery. The implications of these results for psychopharmacological research and the monitoring of psychostimulant effects on children's learning performance in academic settings are discussed.The authors wish to acknowledge and express their sincere appreciation to the graduate and undergraduate student members of the Children's Learning Clinic.     

Altering memory through recall: The effects of cue-guided retrieval processing

Three experiments were designed to investigate the influence of initial recall on memory by assessing delayed recall after different immediate cued-recall tests. In all experiments, subjects performed semantic and phonemic encoding tasks on a word list. The subjects then received a cued-recall test that cued the target using the same word as the context word in the encoding task, a test that cued the target with a word from the same level at which the target was encoded, a test that cued the target with a cue from a different level at which the target was encoded, or no immediate-recall test. One day later, the subjects performed a final cued-recall test in which the type of cue (semantic or phonemic) was varied. Consistently, delayed recall was facilitated primarily when the cue on the immediate test was from the same level as the cue on the delayed test. This pattern of facilitation suggests that immediate cued-recall produces an elaboration of an existing memory representation that is closely tied to the type of cue used on the immediate test.     

Cognitive guidelines for simplifying medical information: Data framing and perception

In this paper, 1 describe psychological guidelines for simplifying medical information — methods to aid the perception and recognition of abnormalities in medical test reports. These techniques resemble natural human editing strategies outlined in prospect theory. The methods pre-edit data as humans do but to reduce human effort. I review empirical studies assessing these techniques and discuss needs for further research.     

Psychological conceptions of randomness

This article presents a critique of the concept of randomness as it occurs in the psychological literature. The first section of our article outlines the significance of a concept of randomness to the process of induction; we need to distinguish random and non-random events in order to perceive lawful regularities and formulate theories concerning events in the world. Next we evaluate the psychological research that has suggested that human concepts of randomness are not normative. We argue that, because the tasks set to experimental subjects are logically problematic, observed biases may be an artifact of the experimental situation and that even if such biases do generalise they may not have pejorative implications for induction in the real world. Thirdly we investigate the statistical methodology utilised in tests for randomness and find it riddled with paradox. In a fourth section we find various branches of scientific endeavour that are stymied by the problems posed by randomness. Finally we briefly mention the social significance of randomness and conclude by arguing that such a fundamental concept merits and requires more serious considerations.     

Teaching self-treatment of cold symptoms to an anoxic brain injured adult

Traumatic brain injury can result in behavioral and physical deficits that require intensive post-acute residential rehabilitation. Behaviors targeted by such programs include basic self-care and living skills. We examined the efficacy of a behavioral training strategy to teach appropriate medical treatment of four different groups of simulated cold symptoms to an anoxic brain injured adult. The strategy included instructor prompting and feedback in the use of written task analyses and picture cues as self-administered prompts. Subsequent to baseline, the participant used written generic task analyses combined with picture cues and then, if necessary, written specific task analyses combined with picture cues to prompt appropriate self-treatment of the four types of colds. Written individualized task analyses, tailored to participant errors, were used to fade specific task analysis prompts and transfer stimulus control to the discriminative stimuli present in the picture cues. A multiple baseline design across responses showed that skill acquisition did not occur after generic task analysis training, but did so after specific task analysis training. The participant responded to all four types of colds for three consecutive trials at 100% correct under baseline conditions. Follow-up results indicated that transfer of stimulus control to the cold symptoms simulated by the picture cues alone did not maintain over time. Correct responding was retrained using generic and, if necessary, individualized task analysis training conditions.