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51.
The authors examined and compared the effect of support-surface perturbations of various magnitudes on lower extremity kinetics of 7 children with cerebral palsy (CP) and 8 typically developing (TD) children. Results showed that the highest velocity tolerated without stepping was slower in children with CP than in either age-matched TD or younger TD children. Multimodal torque profiles were more frequent in children with CP than in TD controls. TD groups temporally and spatially organized torque activation, whereas children with CP activated all joints simultaneously and showed altered torque contribution patterns among joints. Those results suggest that impairments in reactive postural control in children with CP result not only from developmental delay but also from pathology. Evidence for pathology included increased numbers of torque bursts required to regain stability and less efficient temporal and spatial organization of torque activation patterns.  相似文献   
52.
Two chronic, nonfluent aphasia patients participated in overt naming fMRI scans, pre- and post-a series of repetitive transcranial magnetic stimulation (rTMS) treatments as part of a TMS study to improve naming. Each patient received 10, 1-Hz rTMS treatments to suppress a part of R pars triangularis. P1 was a ‘good responder’ with improved naming and phrase length; P2 was a ‘poor responder’ without improved naming.Pre-TMS (10 years poststroke), P1 had significant activation in R and L sensorimotor cortex, R IFG, and in both L and R SMA during overt naming fMRI (28% pictures named). At 3 mo. post-TMS (42% named), P1 showed continued activation in R and L sensorimotor cortex, R IFG, and in R and L SMA. At 16 mo. post-TMS (58% named), he also showed significant activation in R and L sensorimotor cortex mouth and R IFG. He now showed a significant increase in activation in the L SMA compared to pre-TMS and at 3 mo. post-TMS (p < .02; p < .05, respectively). At 16 mo. there was also greater activation in L than R SMA (p < .08). At 46 mo. post-TMS (42% named), this new LH pattern of activation continued. He improved on the Boston Naming Test from 11 pictures named pre-TMS, to scores ranging from 14 to 18 pictures, post-TMS (2–43 mo. post-TMS). His longest phrase length (Cookie Theft picture) improved from three words pre-TMS, to 5–6 words post-TMS.Pre-TMS (1.5 years poststroke), P2 had significant activation in R IFG (3% pictures named). At 3 and 6 mo. post-TMS, there was no longer significant activation in R IFG, but significant activation was present in R sensorimotor cortex. On all three fMRI scans, P2 had significant activation in both the L and R SMA. There was no new, lasting perilesional LH activation across sessions for this patient. Over time, there was little or no change in his activation. His naming remained only at 1–2 pictures during all three fMRI scans. His BNT score and longest phrase length remained at one word, post-TMS.Lesion site may play a role in each patient’s fMRI activation pattern and response to TMS treatment. P2, the poor responder, had an atypical frontal lesion in the L motor and premotor cortex that extended high, near brain vertex, with deep white matter lesion near L SMA. P2 also had frontal lesion in the posterior middle frontal gyrus, an area important for naming (Duffau et al., 2003); P1 did not. Additionally, P2 had lesion inferior and posterior to Wernicke’s area, in parts of BA 21 and 37, whereas P1 did not.The fMRI data of our patient who had good response following TMS support the notion that restoration of the LH language network is linked in part, to better recovery of naming and phrase length in nonfluent aphasia.  相似文献   
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We assessed the efficacy of time delay and peer modeling procedures in increasing autistic children's spontaneous verbalizations of affection. Four autistic children were taught to spontaneously say “I like (love) you” in response to a hug from a familiar person and their mother. Generalization from a free play training setting to free play outdoors and at home was assessed. Ancillary social and affection behaviors were also observed. Results indicated that the time delay was a quick and effective procedure for all the children. Peer modeling was unsuccessful in teaching the target behavior.  相似文献   
55.
Children and youths are being raised by grandparents in greater numbers than would be expected by choice or by chance. These new households represent a transfer of child-rearing responsibilities from an absent or incapacitated parent to an older adult who could also be at risk for disability. This article discusses the implications of this trend for the helping professions, particularly as they apply to interventions required to assure the mental and physical stability of both grandparent and child.  相似文献   
56.
This study was an investigation of contraceptive switching in the context of a 5-wave panel design of diaphragm and pill users from the New York City metropolitan area. The respondents were 525 women between the ages of 14 and 46, who came to one of 10 family planning clinics to obtain birth control, Results indicated a hazard function for switching in which the hazard rate increased in the initial weeks and then gradually declined over time. Clinic experiences on the part of the women were found to alter survivorship trends. Implications of the data for service providers were developed.  相似文献   
57.
A computer interview was developed to collect information about drug use/abuse from high school students. Responses to this interview were compared with those obtained from an identical paper-and-pencil questionnaire given to the same students, in counterbalanced order. Results were comparable for the two methods, but missing data and logically inconsistent answers obtained with the paper-and-pencil questionnaire were not possible with the computer interview. The overwhelming majority of respondents preferred the computer interview as a means of data collection.  相似文献   
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Marjorie Hall Davis 《Zygon》1987,22(3):361-376
Abstract. This paper states the author's understanding of the doctrines of the Christian faith in the light of her scientific background and her interpretation of current evolutionary, neuropsychologi–cal, and other scientific theories. It contains the actual ordination vows and her response to them, based upon an outline of questions suggested by the United Church of Christ.  相似文献   
60.
Autistic children often do not transfer from extra-stimulus prompts, and thus do not utilize a frequent learning aid. It has been hypothesized that this is due to stimulus overselectivity; a failure to respond to simultaneous multiple cues. This study was designed to determine if autistic children who initially respond only to single cues can be taught a set to respond to two cues and subsequently utilize an extra-stimulus (pointing) prompt. Four autistic children were pretested to determine if they could learn a complex visual discrimination by either trial and error or an extra-stimulus prompt fading procedure. Since they did not, the children were then taught to respond to two cues through a multiple-cue training procedure and subsequently tested to determine if they could now utilize a pointing prompt. Results indicated that while all four children initially did not transfer from an extra-stimulus (pointing) prompt, they did so subsequent to multiple-cue training. The results are discussed in terms of implications for treatment (remediating overselectivity) and in relation to normal child development.  相似文献   
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