Functional constraints on sentence processing: A cross-linguistic study

English and Italian provide some interesting contrasts that are relevant to a controversial problem in psycholinguistics: the boundary between grammatical and extra-grammatical knowledge in sentence processing. Although both are SVO word order languages without case inflections to indicate basic grammatical relations, Italian permits far more variation in word order for pragmatic purposes. Hence Italians must rely more than English listeners on factors other than word order. In this experiment, Italian and English adults were asked to interpret 81 simple sentences varying word order, animacy contrasts between the two nouns, topicalization and contrastive stress. Italians relied primarily on semantic strategies while the English listeners relied on word order—including a tendency to interpret the second noun as subject in non-canonical word orders (corresponding to word order variations in informal English production). Italians also made greater use of topic and stress information. Finally, Italians were much slower and less consistent in the application of word order strategies even for reversible NVN sentences where there was no conflict between order and semantics. This suggests that Italian is ‘less’ of an SVO language than English. Semantic strategies apparently stand at the ‘core’ of Italian to the same extent that word order stands at the ‘core’ of English. It is suggested that these results pose problems for claims about a ‘universal’ separation between semantics and syntax, and for theories that postulate a ‘universal’ priority of one type of information over another. Results are discussed in the light of the competition model, a functionalist approach to grammar that accounts in a principled way for probabilistic outcomes and differential ‘weights’ among competing and converging sources of information in sentence processing.     

Hippocampal CA1 kindling but not long-term potentiation disrupts spatial memory performance

Long-term synaptic enhancement in the hippocampus has been suggested to cause deficits in spatial performance. Synaptic enhancement has been reported after hippocampal kindling that induced repeated electrographic seizures or afterdischarges (ADs) and after long-term potentiation (LTP) defined as synaptic enhancement without ADs. We studied whether repeated stimulations that gave LTP or ADs resulted in spatial performance deficits on the radial arm maze (RAM) and investigated the minimal number of ADs required for such deficits. Three experimental groups were run as follows: (1) 5 hippocampal ADs in 1 d (5-AD group), (2) 10 hippocampal ADs in 2 d (10-AD group), and (3) 12 -frequency primed-burst stimulations (PBSs) in 2 d in order to induce LTP without ADs (LTP group). Each experimental group was run together with a control group during the same time period. Rats were first trained in a spatial task on a radial arm maze with four of the eight arms baited, then given control or experimental treatment, and maze performance was tested in the first week (1-4 d) and fourth week (22-25 d) after treatment. Basal dendritic population excitatory postsynaptic potentials (pEPSPs) and medial perforant path (MPP)-evoked dentate gyrus population spike and polysynaptic CA1 excitation were recorded before and after experimental and control treatment. Spatial memory errors, in particular reference memory errors, were significantly higher in the 10-AD kindled group than any other group on the first and fourth week after treatment. Spatial memory errors were not significantly different in the 5-AD and LTP groups as compared with any control groups at any time. Basal dendritic pEPSP in CA1 was enhanced for about 1 wk after 12 PBSs, 10 ADs, or 5 ADs, while the dentate gyrus population spike and CA1 polysynaptic excitation evoked by MPP was increased for up to 4 wk after 10 ADs, but not 12 PBSs. Thus, distributed alteration of multiple synaptic transmission in the entorhinal-hippocampal circuit, but not LTP at the basal dendritic synapses in CA1, may disrupt spatial performance after 10 hippocampal ADs.     

Systemic and local administration of estradiol into the prefrontal cortex or hippocampus differentially alters working memory

The influence of estradiol on learning and memory is dependent on a number of factors. The effects of physiological levels of estradiol on the acquisition of a spatial working memory task mediated by the prefrontal cortex (PFC) and the hippocampus were examined in Experiment 1. Ovariectomized Long-Evans rats received daily injections of estradiol or vehicle were tested on the win-shift version of the radial arm maze. A high dose of estradiol benzoate (5 microg) enhanced acquisition of the task, whereas a low dose of estradiol (0.3 microg) increased the number of errors committed over 17 days of testing. Experiment 2 was conducted to examine site-specific influences of estradiol on spatial working memory in well-trained rats. Saline and estradiol cyclodextrin (0.1 and 0.9 microg) were infused into the prelimbic region of the PFC or dorsal hippocampus 40 min prior to testing on the win-shift task. Infusions of estradiol into both brain areas attenuated saline-infusion disruptions in working memory. Specifically, the higher dose of estradiol facilitated working memory when infused into the PFC, whereas the lower dose of estradiol facilitated performance when infused into the dorsal hippocampus. Moreover, working memory was significantly impaired 24 h after infusions of estradiol into the dorsal hippocampus but not the PFC. These data provide further evidence for the notion that estradiol can dose-dependently alter memory processes and suggest that facilitation or disruptions of working memory by estradiol are site- and time-specific.     

Dynamics of metacognitive judgments: pre- and postretrieval mechanisms

Two experiments examined the temporal course of pre- and postretrieval mechanisms using a new kind of dynamic metacognitive judgment. Experiment 1 presented participants with primed and unprimed triples of remote associates to a target word and required them to provide repeated metacognitive judgments, 4 times during a 12-s interval, about the likelihood that they would later recognize the target. Both familiarity with the words and the processing time were associated with changes in metacognitive evaluations. Experiment 2 placed pre- and postretrieval mechanisms in opposition by transforming an element of a previously primed question. For transformed questions this led to high initial ratings, which decreased over time, while for novel questions the ratings were initially lower and increased with time. The results are discussed in terms of pre- and postretrieval mechanisms interacting over time.