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排序方式: 共有442条查询结果,搜索用时 15 毫秒
371.
Hiroshi Ito Krystian Barzykowski Magdalena Grzesik Sami Gülgöz Ceren Gürdere Steve M.J. Janssen Jessie Khor Harriet Rowthorn Kimberley A. Wade Karlos Luna Pedro B. Albuquerque Devvarta Kumar Arman Deep Singh William Weber Cecconello Sara Cadavid Nicole C. Laird Mario J. Baldassari D. Stephen Lindsay Kazuo Mori 《Journal of applied research in memory and cognition》2019,8(1):68-77
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DiPietro JA Caulfield L Costigan KA Merialdi M Nguyen RH Zavaleta N Gurewitsch ED 《Developmental psychology》2004,40(3):445-456
Longitudinal neurobehavioral development was examined in 237 fetuses of low-risk pregnancies from 2 distinct populations--Baltimore, Maryland, and Lima. Peru--at 20, 24, 28, 32, 36, and 38 weeks gestation. Data were based on digitized Doppler-based fetal heart rate (FHR) and fetal movement (FM). In both groups. FHR declined while variability, episodic accelerations, and FM-FHR coupling increased, with discontinuities evident between 28 and 32 weeks gestation. Fetuses in Lima had higher FHR and lower variability, accelerations, and FM-FHR coupling. Declines in trajectories were typically observed 1 month sooner in Lima, which magnified these disparities. Motor activity differences were less consistent. No sex differences in fetal neurobehaviors were detected. It is concluded that population factors can influence the developmental niche of the fetus. 相似文献
374.
Attachment-related strategies during thought suppression: ironic rebounds and vulnerable self-representations 总被引:5,自引:0,他引:5
The authors conducted 2 studies of attachment-related variations in thought suppression. Participants were asked, or not asked, to suppress thoughts about a relationship breakup and then to perform a Stroop task under high or low cognitive load. The dependent variables were the rebound, of previously suppressed separation-related thoughts (Study 1) and the accessibility of self-traits (Study 2). Under low cognitive load, avoidant individuals did not show any rebound of separation-related thoughts and activated positive self-representations. Under high cognitive load, avoidant participants failed to suppress thoughts of separation and were more likely to activate negative self-representations. Attachment anxiety was associated with high activation of negative self-representations and unremitting separation-related thoughts. The results are discussed in terms of the hidden vulnerabilities of avoidant individuals. 相似文献
375.
BACKGROUND: Brain morphology and physiological measures in schizophrenia have yielded inconsistent results. This may be due in part to difficulties in ascertaining precisely to what degree each measure deviates from its genetically and environmentally determined potential level. We attempted to surmount this problem in a paradigm involving monozygotic twin pair discordant for schizophrenia. In this paradigm, the difference score and reaction time between the unaffected member and affected member of a twin pair should represent the degree of pathologic involvement irrespective of actual level. METHOD: We investigated, using fMRI, the neural substrate underlying encoding and retrieval of aversive and neutral IAPS pictures. RESULTS: An ANOVA on reaction time (RT) between schizophrenia patient (J) and normal sister (D) significant difference, (F = 5.2, p < or = .02) for J had less RT than D. Conversely, the ANOVA for the correct pictures retrieved was insignificant (F = 1.8, p < or = .2). When the brain activity associated with the encoding and retrieval of the aversive pictures was subtracted (J-D and D-J) from that associated with the neutral ones, significant loci of activation were found. During encoding: for J-D the right fusiform gyrus was significantly activated (p < .0001) and for D-J the orbitofrontal cortex was significantly activated (p < .05). During retrieval: for J-D the right anterior cingulate (p < .0001) was activated and the dorsolateral prefrontal cortex (p < .002). For D-J only the cerebellum showed activation (p < .0001). CONCLUSION: Results indicated subtle attenuations in some aspects of memory, thus providing another evidence for cognitive markers of a genetic component in schizophrenia. New approaches in neuropsychiatry-based on genetic methodologies should further define the cerebral physiology responsible for schizophrenia. 相似文献
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377.
Costanzi M Battaglia M Populin R Cestari V Castellano C 《Neurobiology of learning and memory》2003,79(3):204-211
Five sets of experiments were carried out with CD1 mice tested in a one-trial inhibitory avoidance task. In a first set, immediately posttraining administrations of the endogenous ligand for the cannabinoid CB1 receptor anandamide (arachidonylethanolamide) (3 or 6 mg/kg) dose-dependently impaired memory consolidation in mice. A lower dose (1.5 mg/kg) was ineffective. In a second set of experiments, which was carried out at the same time of the first set, preexposure of the animals to the testing apparatus decreased the effect of the drug, as compared with non-preexposed mice. In a third set of experiments, administration of anandamide (3 or 6 mg/kg) prior to the retention test did not affect the retention performance of mice given posttraining injections of either saline or anandamide. These findings indicate that the memory-impairing effects of posttraining administration of anandamide are not state-dependent. In the fourth and fifth series of experiments, carried out with non-preexposed mice, an otherwise ineffective immobilization stress (15 min) enhanced the memory-impairing effect of anandamide, and an otherwise ineffective dose of naltrexone (0.1 mg/kg) completely antagonized the effect. The results are discussed in terms of attenuation of emotionality, resulting in impaired retention, following anandamide administration, and of involvement of opioid system in the effect of this drug. 相似文献
378.
The paper describes the performance of three children with specific visuospatial working memory (VSWM) impairments (Study 1) and three children with visuospatial (nonverbal) learning disabilities (Study 2) assessed with a battery of working memory (WM) tests and with a number of school achievement tasks. Overall, performance on WM tests provides evidence of a double dissociation between spatial-simultaneous processes, underpinning the memorization item positioning in a spatial configuration, and spatial-sequential processes, which allow memorization of the presentation order. In both groups of children of the two studies, a selective impairment either on spatial-sequential or on spatial-simultaneous working memory tasks was observed. These data support the existence of -simultaneous and -sequential modality-dependent processes in visuospatial working memory and confirm the importance of distinguishing between different subtypes of visuospatial (nonverbal) learning-disabled children. 相似文献
379.
The present study investigated the nature of the inhibitory syllable frequency effect, recently reported for normal readers, in a German-speaking dyslexic patient. The reading impairment was characterized as a severe deficit in naming single letters or words in the presence of spared lexical processing of visual word forms. Three visual lexical decision experiments were conducted with the dyslexic patient, an unimpaired control person matched to the patient and a control group: Experiment 1 manipulated the frequency of words and word-initial syllables and demonstrated systematic effects of both factors in normal readers and in the dyslexic patient. The syllable frequency effect was replicated in a second experiment with a more strictly controlled stimulus set. Experiment 3 confirmed the patient's deficit in activating phonological forms from written words by demonstrating that a pseudohomophone effect as observed in the unimpaired control participants was absent in the dyslexic patient. 相似文献
380.