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391.
Costanzi M Battaglia M Populin R Cestari V Castellano C 《Neurobiology of learning and memory》2003,79(3):204-211
Five sets of experiments were carried out with CD1 mice tested in a one-trial inhibitory avoidance task. In a first set, immediately posttraining administrations of the endogenous ligand for the cannabinoid CB1 receptor anandamide (arachidonylethanolamide) (3 or 6 mg/kg) dose-dependently impaired memory consolidation in mice. A lower dose (1.5 mg/kg) was ineffective. In a second set of experiments, which was carried out at the same time of the first set, preexposure of the animals to the testing apparatus decreased the effect of the drug, as compared with non-preexposed mice. In a third set of experiments, administration of anandamide (3 or 6 mg/kg) prior to the retention test did not affect the retention performance of mice given posttraining injections of either saline or anandamide. These findings indicate that the memory-impairing effects of posttraining administration of anandamide are not state-dependent. In the fourth and fifth series of experiments, carried out with non-preexposed mice, an otherwise ineffective immobilization stress (15 min) enhanced the memory-impairing effect of anandamide, and an otherwise ineffective dose of naltrexone (0.1 mg/kg) completely antagonized the effect. The results are discussed in terms of attenuation of emotionality, resulting in impaired retention, following anandamide administration, and of involvement of opioid system in the effect of this drug. 相似文献
392.
The paper describes the performance of three children with specific visuospatial working memory (VSWM) impairments (Study 1) and three children with visuospatial (nonverbal) learning disabilities (Study 2) assessed with a battery of working memory (WM) tests and with a number of school achievement tasks. Overall, performance on WM tests provides evidence of a double dissociation between spatial-simultaneous processes, underpinning the memorization item positioning in a spatial configuration, and spatial-sequential processes, which allow memorization of the presentation order. In both groups of children of the two studies, a selective impairment either on spatial-sequential or on spatial-simultaneous working memory tasks was observed. These data support the existence of -simultaneous and -sequential modality-dependent processes in visuospatial working memory and confirm the importance of distinguishing between different subtypes of visuospatial (nonverbal) learning-disabled children. 相似文献
393.
The present study investigated the nature of the inhibitory syllable frequency effect, recently reported for normal readers, in a German-speaking dyslexic patient. The reading impairment was characterized as a severe deficit in naming single letters or words in the presence of spared lexical processing of visual word forms. Three visual lexical decision experiments were conducted with the dyslexic patient, an unimpaired control person matched to the patient and a control group: Experiment 1 manipulated the frequency of words and word-initial syllables and demonstrated systematic effects of both factors in normal readers and in the dyslexic patient. The syllable frequency effect was replicated in a second experiment with a more strictly controlled stimulus set. Experiment 3 confirmed the patient's deficit in activating phonological forms from written words by demonstrating that a pseudohomophone effect as observed in the unimpaired control participants was absent in the dyslexic patient. 相似文献
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The authors examined the association between excessive reassurance seeking (ERS) in couple relationships and depression, hypothesizing that this association can be explained by attachment anxiety. In Study 1, 72 couples completed questionnaires about ERS, depression, attachment style, and relationship quality. In Study 2, 61 couples completed the same measures in addition to completing daily diary assessments for 14 days. In both studies, ERS was related to depression, but only because of its association with attachment anxiety. The association between attachment anxiety and depression was not mediated by either partner's relationship quality, even though partners noticed each other's ERS. Instead, relationship quality was related primarily to avoidant attachment. These findings were replicated at a daily level of analysis, where interesting details of the underlying processes were revealed. At least in young unmarried couples, depression is associated with attachment anxiety--and one of its facets, ERS--mostly for intrapsychic reasons. 相似文献
396.
Mario Bunge 《Journal of Philosophical Logic》1972,1(3-4):317-328
Concluding remarks Our program is ambitious, as is any attempt to match life (in our case real science) with virtue (e.g., exactness). We want our semantics to be not only simia mathematicae but also ancilla scientiae: built more geometrico and at the same time relevant, nay useful, to live science. The goal of exactness may sound arrogant but is actually modest, for the more we rigorize the more we are forced to leave out of consideration, at least for the time being. As to the service intention: we should try to be of some help to science because the latter faces semantic problems but has no tools of its own for solving them. If it had such tools scientists would not engage in spirited polemics over matters of sense and reference, as they often do. Witness the debates on whether the relativistic and quantum theories are concerned with sentient observers, whether population genetics refers to populations taken as wholes, whether psychology is actually concerned with the brain, and whether the sense of a theory is excreted by its mathematical formalism or is determined by the way the theory is tested.A semantics of science should help settle these and similar issues. Moreover it should give sound advice as to how to formulate scientific theories so as to avoid such imprecisions and ambiguities as may give rise to debates of the kind. Constructing such a semantics, both exact and relevant to science, should be more rewarding than either manufacturing neat but irrelevant theories or pursuing erratic polemics on meaning and meaning changes.
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397.
Mario Saiz Ma. Paz Abalos Claudia Grez Michael Bartfeld Federico Benchin Susana Toloza Madeleine Porre Javiera Falcone 《The Journal of analytical psychology》2023,68(2):301-326
The main objective of this qualitative and quantitative research paper is to explore the occurrences and relations of the anima, animus and androgynous in dreams, with particular emphasis on the consideration of the androgynous in the human psyche. The sample consists of 9 series of dreams (141 dreams in total), from 9 dreamers, 7 women (female sex/gender) and 2 men (male sex/gender), aged 25–57, heterosexual, undergoing Jungian psychotherapy, and presenting couple-related themes. Statistical results and qualitative analysis offer new input for the re-vision of the classical anima-animus model, and the addition of in-depth explorations into the androgynous, paving the way for a new model of psychopathology and psychotherapeutic clinical work, in transition. 相似文献
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Infant Emotion Regulation Strategy Moderates Relations between Self‐Reported Maternal Depressive Symptoms and Infant HPA Activity
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Jennifer E. Khoury Andrea Gonzalez Robert Levitan Mario Masellis Vincenzo Basile Leslie Atkinson 《Infant and child development》2016,25(1):64-83
Children of mothers with depressive symptoms often have high cortisol levels. Research shows that various child characteristics (e.g., attachment pattern, internalizing behaviours, and temperament) moderate this association. We suggest that these characteristics share common variance with emotion regulation strategy. Therefore, we examine infant emotion regulation strategy as a moderator of the association between maternal depressive symptoms and infant hypothalamic–pituitary–adrenal (HPA) function. We hypothesize that infants who utilize more independent emotion regulation strategies and have mothers who report higher depressive symptoms will exhibit elevated cortisol levels. Participants were 193 mothers and infants (15 months old) recruited from the community. Self‐reported maternal depressive symptoms were assessed. Infant independent regulatory behaviours (withdrawal, wandering away, distraction, scanning, orienting to another object) were coded in the context of a Toy Frustration Task. Infant cortisol was collected via saliva samples at baseline, +20, and +40 minutes. Results indicate that infant emotion regulation strategy moderates the relation between mothers' self‐reported depressive symptoms and infant total cortisol output (AUCG) and cortisol reactivity (AUCI). Infants who employed more independent regulatory behaviours and have mothers with higher depressive symptoms experience greater cortisol secretion. We discuss the findings in relation to parent‐infant interactions and the adaptive nature of emotion regulation strategies, as they relate to HPA regulatory capacities. Copyright © 2015 John Wiley & Sons, Ltd. 相似文献