Severity of childhood attention-deficit hyperactivity disorder--a risk factor for personality disorders in adult life?

Some evidence points to an increased rate of cluster B and C personality disorders (PDs) in adult ADHD patients. In order to assess axis II disorders comprehensively we used the diagnostic instrument of the WHO. In sixty adult out-patients with ADHD according to DSM-IV criteria PDs were assessed with the International PD Examination (IPDE) and severity of childhood ADHD with the Wender-Utah-Rating Scale (WURS). We found at least one PD in 25% of cases. Cluster C PDs were most common (36.6%) followed by Cluster B (23.3%) and A (8.3%). Avoidant (21.7%) and borderline (18.3%) were the most frequent single PD entities. ADHD patients with PD suffered from significantly more severe childhood ADHD compared to those without co-occurring PD. Applying the IPDE we confirmed a high number of PDs among adult ADHD patients. Our findings point to a higher vulnerability for the development of PDs in patients with severe childhood ADHD.     

Structure and measurement of depression in youths: applying item response theory to clinical data

Our goals in this article were to use item response theory (IRT) to assess the relation of depressive symptoms to the underlying dimension of depression and to demonstrate how IRT-based measurement strategies can yield more reliable data about depression severity than conventional symptom counts. Participants were 3,403 children and adolescents from 12 contributing clinical and nonclinical samples; all participants had received the Kiddie Schedule of Affective Disorders and Schizophrenia for School-Aged Children. Results revealed that some symptoms reflected higher levels of depression and were more discriminating than others. Furthermore, use of IRT-based information about symptom severity and discriminability in the measurement of depression severity was shown to reduce measurement error and increase measurement fidelity.     

A behavior-based circuit model of how outcome expectations organize learned behavior in larval Drosophila

Drosophila larvae combine a numerically simple brain, a correspondingly moderate behavioral complexity, and the availability of a rich toolbox for transgenic manipulation. This makes them attractive as a study case when trying to achieve a circuit-level understanding of behavior organization. From a series of behavioral experiments, we suggest a circuitry of chemosensory processing, odor-tastant memory trace formation, and the "decision" process to behaviorally express these memory traces--or not. The model incorporates statements about the neuronal organization of innate vs. conditioned chemosensory behavior, and the types of interaction between olfactory and gustatory pathways during the establishment as well as the behavioral expression of odor-tastant memory traces. It in particular suggests that innate olfactory behavior is responsive in nature, whereas conditioned olfactory behavior is captured better when seen as an action in pursuit of its outcome. It incorporates the available neuroanatomical and behavioral data and thus should be useful as scaffold for the ongoing investigations of the chemo-behavioral system in larval Drosophila.     

Interracial contact and changes in the racial attitudes of white college students

College campuses are among the most racially diverse settings in our segregated society. For many students, especially non-Hispanic whites, college represents the first time they have come into significant contact with members of other groups. Using data from the National Longitudinal Survey of Freshmen, this paper explores the effects of campus diversity and various types of interracial contact on the racial and ethnic attitudes of white students over the course of four years in college. The findings are largely consistent with the contact hypothesis, particularly with respect to changes in attitudes towards blacks. White students who report having a close friend who is black and those who have dated or had a romantic partner who is black express less social distance towards blacks in their senior year, as do white students who were involved in extracurricular activities in which blacks are the majority. Participating in extracurricular activities dominated by blacks is also associated with more positive views of the impact of affirmative action on academic standards expressed as students were leaving college. Although there is evidence that both stereotypes and social distance towards groups are mitigated by intergroup contact, stereotypes appeared to be somewhat more resistant to change. The findings suggest that institutions should continue efforts to diversify their student populations, and also promote involvement in extracurricular activities for students from all groups.     

Frühkindlicher Autismus

Eine kurze Geschichte der Diagnose des frühkindlichen Autismus leitet diesen übersichtsartikelein. Die autistische St?rung zeichnet sich durch drei Hauptsymptomgruppen aus: St?rung der sozialen Interaktion, St?rung der Kommunikation, und stereotype, eingeschr?nkte Verhaltensmuster und Interessen. Aktuelle Kenntnisse im Bereich der ?tiopathogenese wurden kurz zusammengefasst. Diagnostische und differenzialdiagnostische Grundlagen werden diskutiert. Ein kurzer überblick der Pharmakotherapie des Autismus schlie?t die übersicht.     

Predictors of the change in self-stigma following a single session of group counseling

One of the major obstacles to seeking psychological help is the stigma associated with counseling and therapy. Self-stigma, the fear of losing self-respect or self-esteem as a result of seeking help, is an important factor in the help-seeking process. In the present study, college students meeting a clinical cutoff for psychological symptoms participated in 1 session of group counseling that either contained therapist self-disclosure or did not. In general, participants reported significantly less self-stigma following the session. Working alliance-bond and session depth significantly predicted the change in self-stigma. Furthermore, self-stigma (as well as bond, depth, psychological symptoms, and being female) predicted the intention to seek help following the session. Self-stigma and session depth also predicted interest in continuing with counseling. The therapist self-disclosure condition, however, had no effect on the change in self-stigma, intentions to seek help, or interest in continuing with group counseling.     

The Essential Nature of Sharing in Science

Advances in science are the combined result of the efforts of a great many scientists, and in many cases, their willingness to share the products of their research. These products include data sets, both small and large, and unique research resources not commercially available, such as cell lines and software programs. The sharing of these resources enhances both the scope and the depth of research, while making more efficient use of time and money. However, sharing is not without costs, many of which are borne by the individual who develops the research resource. Sharing, for example, reduces the uniqueness of the resources available to a scientist, potentially influencing the originator’s perceived productivity and ultimately his or her competitiveness for jobs, promotions, and grants. Nevertheless, for most researchers—particularly those using public funds—sharing is no longer optional but must be considered an obligation to science, the funding agency, and ultimately society at large. Most funding agencies, journals, and professional societies now require a researcher who has published work involving a unique resource to make that resource available to other investigators. Changes could be implemented to mitigate some of the costs. The creator of the resource could explore the possibility of collaborating with those who request it. In addition, institutions that employ and fund researchers could change their policies and practices to make sharing a more attractive and viable option. For example, when evaluating an individual’s productivity, institutions could provide credit for the impact a researcher has had on their field through the provision of their unique resources to other investigators, regardless of whether that impact is reflected in the researcher’s list of publications. In addition, increased funding for the development and maintenance of user-friendly public repositories for data and research resources would also help to reduce barriers to sharing by minimizing the time, effort, and funding needed by individual investigators to comply with requests for their unique resource. Indeed, sharing is an imperative, but it is also essential to find ways to protect for both the original owner of the resource and those wishing to share it.     

Facial expressions modulate the ontogenetic trajectory of gaze-following among monkeys

Gaze-following, the tendency to direct one's attention to locations looked at by others, is a crucial aspect of social cognition in human and nonhuman primates. Whereas the development of gaze-following has been intensely studied in human infants, its early ontogeny in nonhuman primates has received little attention. Combining longitudinal and cross-sectional observational data from Barbary macaques at 'La Forêt des Singes', we show here that gaze-following among conspecifics develops within the first year of life with a rapid increase between 5 and 6 months, reaching adult levels at 1 year. Sex, rank, and relatedness of the animal whose gaze the subject followed did not affect gaze-following rates. Interestingly, however, the behavior was enhanced in all age classes if a gaze-cue was accompanied by a facial expression. Furthermore, the effect of facial expressions had a modulatory influence on the ontogenetic trajectory of gaze-following, suggesting that it is of functional significance in the development of the behavior. Follow-up analyses revealed that one specific facial expression that is given in response to social interactions between third parties was particularly efficient in eliciting gaze-following responses, indicating the importance of cues that are able to guide the acquisition of social information. Taken together, these results suggest that the development and the operation of gaze-following are tuned to the social and physical characteristics of a species' environment.     

Identification of Early Child and Family Risk Factors for Aggressive Victim Status in First Grade

This prospective investigation sought to discriminate children who were both aggressive towards and victimized by peers in the first grade, from those who were only aggressive, only victimized, or neither (i.e., socially adjusted), using early child and family risk factors. Two hundred thirty-eight children, their mothers, and teachers participated in a longitudinal study since birth. All three aggressor/victim subgroups showed greater temperamental dysregulation than the socially adjusted children, but only aggressive victims had significantly poorer social perception skills. Aggressive victims were distinguished from aggressors by greater exposure to maternal depression and from victims by lower levels of early inhibition, but they shared the experiences of negative family emotional expressiveness with aggressors and greater mother-child negativity with victims. The identification of early risk factors is crucial to prevention and early intervention efforts that have the potential to attenuate the long term emotional, social, and academic problems associated with aggressive victim status.     

Attentional mechanisms associated with repressive distancing

This research explores the role of attentional shift and disengagement in repressive distancing. During a target-detection task in which emotional and neutral facial expressions were used as cues, participants received performance feedback intended to elicit a negative emotional reaction that rendered the task either threatening or not threatening to self-concept. When the task was perceived to threaten self-concept, repressors distanced themselves by rapidly disengaging their attention from the facial expressions rather than by slowly shifting or not shifting their attention to the facial expressions. Attentional disengagement was accompanied by sympathetic nervous system activity suggestive of a defense response. This research provides further insight into the nature and consequences of the interplay of dispositional tendencies, situational contexts, and higher order cognitive influences in attentional behavior.