A Preliminary Examination of Sexual Orientation as a Social Vulnerability for Experiencing HIV/AIDS-related Stigma

This investigation is a preliminary examination of sexual orientation as a social vulnerability for experiencing HIV/AIDS-related stigma, specifically concerns about disclosure and public attitudes. Participants were 36 heterosexual men and 82 gay men with HIV/AIDS. Consistent with prediction, a heterosexual sexual orientation was significantly associated with HIV/AIDS disclosure concerns. This effect was evident after controlling for various demographic variables, CD4 T-cell count, time since HIV diagnosis, self-esteem, and coping styles. Also, as predicted, similar levels of enacted stigma were evident regardless of sexual orientation. Further work is needed to understand the process of HIV/AIDS disclosure for heterosexual men with this illness and to differentiate the experience of HIV/AIDS-related stigma among gay and straight men with HIV/AIDS.     

Diffusion of entitlement: An inhibitory effect of scarcity on consumption

Four studies demonstrated that increasing a desirable commodity's scarcity (i.e., decreasing its supply or increasing demand for it) can inhibit people from claiming the commodity for themselves, thereby delaying its consumption. In Study 1, participants were slower to claim a commodity when its supply was limited versus unlimited. In Study 2, participants expressed more disapproval of someone who took the last commodity compared to the second-last commodity. Participants in Study 3 anticipated that increased demand for a commodity would make them less likely to claim it despite wanting it more. Study 4 showed that the more participants there were who could claim a commodity, the longer it went unclaimed. The inhibitory effect of scarcity was mediated by diminished entitlement to the commodity (Study 3), and increasing entitlement reduced the inhibition against taking scarce commodities (Studies 1 and 2). These findings are discussed in the context of individuals' concern with equality.     

A domain-specific validation of the core self-evaluations scale

Core self-evaluations have been recently proposed as indicating positive self-concept and as being predictive of various forms of subjective wellbeing. In an effort to further validate the Core Self-Evaluations Scale (CSES), structural equation modeling (SEM) was employed in three independent samples of university students to examine the extent to which scores on the Core Self-Evaluations Scale predicted two measures of university satisfaction. Good fit was found for models that also controlled for status in college, student major, class satisfaction, life satisfaction, college grade point average, and overall grade fairness. Statistically significant relationships corrected for attenuation by SEM between scores on the Core Self-Evaluations Scale and university satisfaction range from .24 to .37.     

Psychological stress in childhood and susceptibility to the chronic diseases of aging: moving toward a model of behavioral and biological mechanisms

Among people exposed to major psychological stressors in early life, there are elevated rates of morbidity and mortality from chronic diseases of aging. The most compelling data come from studies of children raised in poverty or maltreated by their parents, who show heightened vulnerability to vascular disease, autoimmune disorders, and premature mortality. These findings raise challenging theoretical questions. How does childhood stress get under the skin, at the molecular level, to affect risk for later diseases? And how does it incubate there, giving rise to diseases several decades later? Here we present a biological embedding model, which attempts to address these questions by synthesizing knowledge across several behavioral and biomedical literatures. This model maintains that childhood stress gets "programmed" into macrophages through epigenetic markings, posttranslational modifications, and tissue remodeling. As a consequence these cells are endowed with proinflammatory tendencies, manifest in exaggerated cytokine responses to challenge and decreased sensitivity to inhibitory hormonal signals. The model goes on to propose that over the life course, these proinflammatory tendencies are exacerbated by behavioral proclivities and hormonal dysregulation, themselves the products of exposure to early stress. Behaviorally, the model posits that childhood stress gives rise to excessive threat vigilance, mistrust of others, poor social relationships, impaired self-regulation, and unhealthy lifestyle choices. Hormonally, early stress confers altered patterns of endocrine and autonomic discharge. This milieu amplifies the proinflammatory environment already instantiated by macrophages. Acting in concert with other exposures and genetic liabilities, the resulting inflammation drives forward pathogenic mechanisms that ultimately foster chronic disease.     

Cytokines and memory across the mature life span of women

Increasing evidence suggests a role of the immune system in modulation of cognition, but details on affected memory systems are largely lacking. We therefore aimed to study the relation between selected cytokines and subsets of memory, and the impact of age in these relations. From a random population-based sample (the Betula Prospective Cohort Study), 298 women (age 45-90) were studied in terms of episodic recall and recognition, semantic fluency and knowledge, and prospective memory. Circulating cytokines of relevance for cognition and aging were measured with ELISA. Levels of interleukin (IL)-6 and sIL-2R were significantly and negatively associated with most cognitive variables, while the opposite was true for IL-1β. Age shared substantial variance with both cytokines and memory, and turned most correlations non-significant when controlled for together with education, BMI and presence of disease. Interactions between age and cytokines were further analyzed in multiple regressions. For IL-6, significant negative interactions with age were found for semantic fluency (p<0.05) and prospective memory (p<0.01), and for sIL-2R in predicting semantic knowledge (p<0.05), indicating an increased negative impact of these cytokines on memory with increasing age. In conclusion, the study indicates a relation between cytokines and memory that appears to be largely mediated by age, and supports the suggestion that cytokine dysregulation with higher age may interact with cognitive aging.     

Understanding the centrality deficit: Insight from foreign language learners

This study replicated and extended a phenomenon in the text memory literature referred to as the centrality deficit Miller & Keenan (Annals of Dyslexia 59:99–113, 2009). It examined how reading in a foreign language (L2) affects one’s text representation and ability to recall the most important information. Readers recalled a greater proportion of central than of peripheral ideas, regardless of whether reading in their native language (L1) or a foreign language (L2). Nonetheless, the greatest deficit in participants’ L2 recalls, as compared with L1 recalls, was on the central, rather than the peripheral, information. This centrality deficit appears to stem from resources being diverted from comprehension when readers have to devote more cognitive resources to lower level processes (e.g., L2 word identification and syntactic processing), because the deficit was most evident among readers who had lower L2 proficiency. Prior knowledge (PK) of the passage topic helped compensate for the centrality deficit. Readers with less L2 proficiency who did not have PK of the topic displayed a centrality deficit, relative to their L1 recall, but this deficit dissipated when they did possess PK.     

Fusion prevents the redundant signals effect: evidence from stereoscopically presented stimuli

In a simple reaction time (RT) experiment, visual stimuli were stereoscopically presented either to one eye (single stimulation) or to both eyes (redundant stimulation), with brightness matched for single and redundant stimulations. Redundant stimulation resulted in two separate percepts when noncorresponding retinal areas were stimulated, whereas it resulted in a single fused percept when corresponding areas were stimulated. With stimulation of noncorresponding areas, mean RT was shorter to redundant than to single stimulation, replicating the redundant signals effect (RSE) commonly found with visual stimuli. With stimulation of corresponding areas, however, no RSE was observed. This suggests that the RSE is driven by the number of percepts rather than by the number of stimulated receptors or sensory organs. These results are consistent with previous findings in the auditory modality and have implications for models of the RSE.     

The Emotional Citizen: Emotion as a Function of Political Sophistication

Scholars and popular commentators have often stereotyped emotion as a tool that citizens use to reason about politics in place of hard fact and critical thought. Indeed, critics have often seen emotion as a potentially dangerous force that can sway the unsophisticated masses to undesirable ends. This article challenges the view that emotion is an outgrowth of low sophistication, arguing that high sophisticates are more likely to experience emotion in reaction to politics and that emotions are more influential on the political behavior of high sophisticates. Drawing upon appraisal theory, this article develops a theory of how political engagement elicits emotionality about politics, and how emotion interacts with understanding and motivation to produce its greatest impact on the behavior of those citizens who are the most politically sophisticated. Behavioral effects are examined in the contexts of presidential voting behavior and Iraq War policy attitudes. Hypotheses are tested on pooled American National Election Studies (ANES) data and an original web‐based survey of undergraduates.     

Proprioceptive impairment and postural orientation control in Parkinson's disease

Impairment of postural control is a common consequence of Parkinson’s disease (PD). Increasing evidences demonstrate that the pathophysiology of postural disorders in PD includes deficits in proprioceptive processing and integration. However, the nature of these deficits has not been thoroughly examined. We propose to establish a link between proprioceptive impairments and postural deficits in PD using two different experimental approaches manipulating proprioceptive information. In the first one, the subjects stood on a platform that tilted slowly with oscillatory angular movements in the frontal or sagittal planes. The amplitude and frequency of these movements were kept below the semicircular canal perception threshold. Subjects were asked to maintain vertical body posture with and without vision. The orientations of body segments were analyzed. In the second one, the postural control was tested using the tendon-vibration method, which is known to generate illusory movement sensations and postural reactions. Vibrations were applied to ankle muscles. The subject’s whole-body motor responses were analyzed from center of pressure displacements.In the first experiment, the parkinsonian patients (PP) were unable to maintain the vertical trunk orientation without vision. Their performances with vision improved, without fully reaching the level of control subjects (CS). In the second experiment, the postural reactions of the PP were similar to those of the CS at the beginning of the perturbation and increased drastically at the end of the perturbation’s period as compared to those of CS and could induce fall.These results will bring new concepts to the sensorimotor postural control, to the physiopathology of posture, equilibrium and falls in PD and to the role of basal ganglia pathways in proprioception integration. Nevertheless, in order to assess precisely the role played by sensorimotor integration deficits in postural impairments in PD, further studies establishing the links between clinical features and abnormalities are now required.     

Unskilled but aware: reinterpreting overconfidence in low-performing students

People are generally overconfident in their self-assessments and this overconfidence effect is greatest for people of poorer abilities. For example, poor students predict that they will perform much better on exams than they do. One explanation for this result is that poor performers in general are doubly cursed: They lack knowledge of the material, and they lack awareness of the knowledge that they do and do not possess. The current studies examined whether poor performers in the classroom are truly unaware of their deficits by examining the relationship between students' exam predictions and their confidence in these predictions. Relative to high-performing students, the poorer students showed a greater overconfidence effect (i.e., their predictions were greater than their performance), but they also reported lower confidence in these predictions. Together, these results suggest that poor students are indeed unskilled but that they may have some awareness of their lack of metacognitive knowledge.