Tensions and Opportunities in Convergence: Shifting Concepts of Disease in Emerging Molecular Medicine

The convergence of biomedical sciences with nanotechnology as well as ICT has created a new wave of biomedical technologies, resulting in visions of a ‘molecular medicine’. Since novel technologies tend to shift concepts of disease and health, this paper investigates how the emerging field of molecular medicine may shift the meaning of ‘disease’ as well as the boundary between health and disease. It gives a brief overview of the development towards and the often very speculative visions of molecular medicine. Subsequently three views of disease often used in the philosophy of medicine are briefly discussed: the ontological or neo-ontological, the physiological and the normative/holistic concepts of disease. Against this background two tendencies in the field of molecular medicine are highlighted: (1) the use of a cascade model of disease and (2) the notion of disease as a deviation from an individual pattern of functioning. It becomes clear that molecular medicine pulls conceptualizations of disease and health in several, partly opposed directions. However, the resulting tensions may also offer opportunities to steer the future of medicine in more desirable directions.     

Maternal attachment disturbances in failure to thrive

Psychological characteristics pertaining to attachment relationships were measured in mothers of 25 hospitalized failure-to-thrive (FTT) infants and mothers of 25 hospitalized, normally growing infants. The groups were matched for race, socioeconomic status, maternal education, and infant's age and sex. Results showed that 96% of mothers of FTT infants were classified as insecure with respect to attachment, as assessed by the Adult Attachment Interview (George, Kaplan, & Main, 1985), compared to 60% of control group mothers. Lack of resolution of mourning over the loss of a loved one was found in 52% of the mothers in the FTT group and in 32% of mothers in the control group. Mothers of FTT infants reported receiving less support from their families and rated their current relationship with their partner as less satisfying. These findings provide empirical support for the widely held clinical notion that FTT in infants is often a relationship disorder between infant and caregiver.     

Representing the internal world: Response to Seligman

Two major points raised by Seligman in his commentary are discussed. First, attachment research has developed empirical methods for studying internal representations. In our view, this adds to our understanding rather than overvalues attachment as a construct or as a methodological approach. Second, we suggest that nomothetic (the study of general laws which hold for groups of individuals) and idiographic (the study of specific laws which hold for individuals) approaches to knowledge are complementary rather than competitive and that each will make use of certain observations in different ways. We point out that the purpose of the Journal's Special Issue that occasioned Seligman's commentary was to acquaint readers with empirical advances in the study of internal representations. We look forward to a continuing dialogue among clinicians, researchers, and theoreticians.     

The Changing Challenges in the Lives of Three Generations of Professional Women

The American Journal of Psychoanalysis -     

Empowering Mimicry: Female Leader Role Models Empower Women in Leadership Tasks Through Body Posture Mimicry

Sex Roles - In two studies we investigated the behavioral process through which visible female leader role models empower women in leadership tasks. We proposed that women tend to mimic the...     

Developmental stimulation in child care centers contributes to young infants’ cognitive development

This study examined whether the quality of caregiver behavior in child care centers contributes to infant cognitive development at 9 months of age. Sixty-four infants (34 boys) were observed with their primary caregivers in child care centers at 3, 6, and 9 months of age. Caregiver behavior was rated for sensitivity and for stimulation of infant development during one-to-one caregiving interactions. Infant cognitive development was assessed using the Bayley Scales of Infant Development-II (Mental Development Index). Higher levels of developmental stimulation in the centers predicted higher levels of infant cognitive development at 9 months, beyond infant cognitive development at 3 months (just before entering child care), parental education, and maternal sensitivity. The results suggest that even small increases in developmental stimulation provided in child care centers in the first year of life may foster infants’ cognitive development.     

Testing a new cognitive behavioural treatment for obesity: A randomized controlled trial with three-year follow-up

It is remarkably difficult for people with obesity to maintain a new lower weight following weight loss. The aim of the present study was to examine the immediate and longer-term effects of a new cognitive behavioural treatment that was explicitly designed to minimise this post-treatment weight regain. One hundred and fifty female participants with obesity were randomized to the new treatment, behaviour therapy (the leading alternative psychological treatment) or guided self-help (a minimal intervention). Both of the main treatments resulted in an average weight loss of about ten percent of initial weight whereas weight loss was more modest with guided self-help. The participants were subsequently followed-up for three years post-treatment. The great majority regained almost all the weight that they had lost with the new treatment being no better than the behavioural treatment in preventing weight regain. These findings lend further support to the notion that obesity is resistant to psychological methods of treatment, if anything other than a short-term perspective is taken. It is suggested that it is ethically questionable to claim that psychological treatments for obesity “work” in the absence of data on their longer-term effects.