Lymphocyte subsets, cardiovascular measures and anxiety state before and after a professional examination

Controversies exist regarding the impact of psychological stress on the functioning of the immune system in humans. The aim of the present study, therefore, was to evaluate whether the condition of a pre-exam stress may or not modify resting lymphocyte subsets, as well as blood pressure and heart rate. About 22 medical residents of both sexes not suffering from any medical or psychiatric disorder were included in the study. Anxiety levels were measured by means of the Hamilton rating scale for anxiety (HRSA) and anxiety traits by means of the panic-agoraphobic spectrum self-report (PAS-SR) version and the obsessive-compulsive spectrum self-report (OBS-SR) version. The results showed that systolic blood pressure and heart rate increased significantly just before sitting an examination (t(1)) in all subjects, as compared with a calm situation (t(2)), in parallel with the increase in the HRSA total score, while no significant difference was observed in lymphocyte subsets at the two assessment times. However, men had a higher number of CD4+ cells than women at t(1) and t(2), while women showed a higher heart rate at t(1). In addition, significant correlations between CD4+ lymphocyte count and heart rate at t(1) or HRSA at t(2) were detected. These findings indicate that the acute stress determined by sitting for examination provokes changes in autonomic nervous system parameters, such as blood pressure and heart rate, as well as in the subjective feeling of anxiety, as shown by the increased HRSA total scores, which were not paralleled by modifications of lymphocyte subsets. However, individual differences, related to both sex and personality traits yet to be identified, seem to have an impact in shaping the stress response.     

Seeing is believing: how participants in different subcultures judge people's credulity

We presented a scenario in which a protagonist saw an object in Location A but later heard a message saying it was in Location B. Participants judged where the protagonist believed the object was. In one condition, participants had additional information that the message was true. Those from an individualistic subculture tended to judge that the protagonist believed the message when they (the participants) knew it was true but disbelieved the message when they had no additional information. In contrast, participants from a collectivist subculture tended to judge that the protagonist believed the message in both circumstances. The results suggest that culture is related with subtle aspects of understanding the mind and especially how people evaluate messages. Copyright © 2006 John Wiley & Sons, Ltd.     

Informal Proofs and Mathematical Rigour

The aim of this paper is to provide epistemic reasons for investigating the notions of informal rigour and informal provability. I argue that the standard view of mathematical proof and rigour yields an implausible account of mathematical knowledge, and falls short of explaining the success of mathematical practice. I conclude that careful consideration of mathematical practice urges us to pursue a theory of informal provability.     

Turning a blind eye to double blind line‐ups

Although psychologists have urged police officers to use double blind line‐up procedures during their investigations, police officers state that these would be difficult to administer and most have been reluctant to implement this change. Four studies examine whether lay people's judgements about the guilt of a suspect vary according to whether a brief written summary of a case described the identification procedure as double blind or non‐double blind. The effects were all small (and almost all non‐significant). Most people do not treat double blind line‐ups differently from non‐double blind line‐ups when assessing the guilt of a defendant. Either police investigators should stop using this biased method or police investigators and others in the judicial system (e.g. jurors, judges) should be informed of this bias when evaluating results from any line‐up. Copyright © 2009 John Wiley & Sons, Ltd.     

A focus on commitment: the roles of transformational and transactional leadership and self-regulatory focus in fostering organizational and safety commitment

The concept of employees’ commitment is one of the most challenging concepts in the management, organizational behaviour and human resource management literatures and research. The current study focuses on the construct of commitment as an emotional attitude, and expands the concept of general organizational commitment to a new more specific form of commitment, commitment to safety. Furthermore, commitment theorists commonly identify leadership as an important contributing factor to the development of organizational commitment. We aim to explain an underlying motivational mechanism, self-regulatory foci, through which leadership styles foster followers’ commitment. Results of three studies that used different methods (field and experimental), within different samples, demonstrated that transformational leadership was positively associated with followers’ promotion focus, which in turn was positively associated with both followers’ general and affective commitment to safety. Prevention focus mediated the positive relationship between a transactional active leadership style and both followers’ general and continuance commitment to safety. The implications of the findings for theory and practice are further discussed.     

Electrophysiological evidence for size invariance in masked picture repetition priming

This experiment examined invariance in object representations through measuring event-related potentials (ERPs) to pictures in a masked repetition priming paradigm. Pairs of pictures were presented where the prime was either the same size or half the size of the target object and the target was either presented in a normal orientation or was a normal sized mirror reflection of the prime object. Previous masked repetition priming studies have found a cascade of priming effect sensitive to perceptual (N190/P190) and semantic (N400) properties of the stimulus. This experiment found that both early (N190/P190 effects) and later effects (N400) were invariant to size, whereas only the N190/P190 effect was invariant to mirror reflection. The combination of a small prime and a mirror reflected target led to no significant priming effects. Taken together, the results of this set of experiments suggests that object recognition, more specifically, activating an object representation, occurs in a hierarchical fashion where overlapping perceptual information between the prime and target is necessary, although not always sufficient, to activate a higher level semantic representation.     

Developmental path between language and autistic‐like impairments: a twin study

Autism spectrum disorders (ASDs) are diagnosed when individuals show impairments in three behavioural domains: communication, social interactions, and repetitive, restrictive behaviours and interests (RRBIs). Recent data suggest that these three sets of behaviours are genetically heterogeneous. Early language delay is strongly associated with ASD, but the basis for this association and the relationship with individual sub‐domains of ASD has not been systematically investigated. In the present study, data came from a population‐based twin sample with language development data at 2–4 years, measured by the MacArthur Communicative Development Inventory (MCDI), and data at 8 years using the Childhood Asperger Syndrome Test (CAST). For the total CAST and the three subscales at 8 years, approximately 300 same‐sex twin pairs were selected as showing extreme autistic‐like traits (ALTs), defined here as pairs in which at least one member of the twin pair scored in the highest 5% of the distribution. Phenotypic analyses indicated that children showing extreme social and communication ALTs (but not the RRBI subscale) at 8 years were below average in language development at 2–4 years. A regression model for selected twin data suggested that genetic influences account for this overlap, but that these effects are only in part mediated by genes that are shared between language and extreme autistic traits. Copyright © 2008 John Wiley & Sons, Ltd.     

Impulsivity as a predictor of newly diagnosed depression

Depression is a severe mental disorder, whose onset has been related to environmental, genetic and personality factors. This study examined the association between impulsivity and incidence of depression. Logistic regression models were related to prospective data from two surveys (2-year time lag) conducted in a large cohort of hospital employees (N= 4,505). Only respondents with no history of depression at baseline were included. Impulsivity was predictive of the onset of depression (OR = 1.95, CI 95%= 1.28-2.97) after adjustment for age, sex and education. This association remained statistically significant after additional adjustment for a variety of baseline characteristics, such as smoking, alcohol consumption, and size of social network. A measure of mental distress (GHQ-12 responses), which may serve as a proxy measure for undiagnosed depression, was also associated with impulsivity. Impulsivity appears to be a distinct personality factor that may contribute to the onset of depressive illness in adults.     

When "macrocefalo (macrocephalous)" is read "minicervello (minibrain)": evidence from a single case study

We report the case of a patient who showed a marked deficit in compound reading after almost complete recovery from his aphasic disturbances. Omission of one of the two compound components was his most frequent type of error. The patient also produced many paraphasias, which always respected the compound structure of the target. Similar errors were found on tasks of naming and writing to dictation. A deficit in retrieving the verb component of verb-noun compounds was also observed, consistent with the patient's residual agrammatism, and with decomposition at some point in processing. We suggest that this pattern of performance is compatible with a dual route model that hypothesises two stages of compound retrieval, a whole word stage followed by a decomposition into two constituent morphemes.     

Delay discounting as emotional processing: An electrophysiological study

Both theoretical models and functional imaging studies implicate the involvement of emotions within the delay discounting process. However, defining this role has been difficult to establish with neuroimaging techniques given the automaticity of emotional responses. To address this, the current study examined electrophysiological correlates involved in the detection and evaluation of immediate and delayed monetary outcomes. Our results showed that modulation of both early and later ERP components previously associated with affective stimuli processing are sensitive to the signalling of delayed rewards. Together with behavioural reaction times that favoured immediacy, we demonstrated, for the first time, that time delays modify the incentive value of monetary rewards via mechanisms of emotional bias and selective visual attention. Furthermore, our data are consistent with the hypothesis that delayed and thus intangible rewards are perceived less saliently, and rely on emotion as a common currency within decision making. This study provides a new approach to delay discounting and highlights a potential novel route through which delay discounting may be investigated.