Relationship of Mindfulness to Distress and Cortisol Response in Adolescent Girls At-Risk for Type 2 Diabetes

Altered stress response theoretically contributes to the etiology of cardiometabolic disease. Mindfulness may be a protective buffer against the effects of stress on health outcomes by altering how individuals evaluate and respond to stress. We engaged adolescent girls at risk for developing Type 2 diabetes in a cold-pressor test in order to determine the relationship of dispositional mindfulness to cortisol response and subjective stress, including perceived pain and unpleasantness during the stressor, and negative affect following the stressor. We also evaluated mindfulness as a moderator of psychological distress (depressive/anxiety symptoms) and stress response. Participants were 119 girls age 12–17 years with overweight/obesity, family history of diabetes, and mild-to-moderate depressive symptoms. Greater mindfulness was associated with less perceived pain and negative affect, but was unrelated to cortisol response to the stressor. Regardless of mindfulness, greater depressive/anxiety symptoms related to a more blunted cortisol response. Mindfulness might promote better distress tolerance in adolescents at risk for diabetes by altering how youth perceive and relate to acute stress, rather than through altering the physiological stress response. At all levels of mindfulness, depressive/anxiety symptoms relate to greater blunting of cortisol response. Findings contribute to emerging literature on the role of mindfulness in promoting the mental and physical health and well-being of individuals at risk for Type 2 diabetes.     

Time Costs for Genetic Counseling in Preconception Carrier Screening with Genome Sequencing

Advances in technology and the promise of personalized health care are driving greater use of genome sequencing (GS) for a variety of clinical scenarios. As health systems consider adopting GS, they need to understand the impact of GS on the organization and cost of care. While research has documented a dramatic decrease in the cost of sequencing and interpreting GS, few studies have examined how GS impacts genetic counseling workloads. This study examined the time needed to provide genetic counseling for GS in the context of preconception carrier screening. Genetic counselors prospectively reported on the time spent in the results disclosure process with 107 study participants who were part of the NextGen study. We found that the median time for results disclosure was 64 min (ranged from 5 to 229 min). Preparation work was the most time-consuming activity. Qualitative data from journal entries, debrief interviews with genetic counselors, and detailed case conference notes provided information on factors influencing time for results disclosure and implications for practice. Results suggest that expanded carrier screening could require significant increases in genetic counseling time, unless we are able to generate new resources to reduce preparation work or develop other strategies such as the creation of new models to deliver this type of service.     

The im-materiality of urban religion: towards an ethnography of urban religious aspirations

In recent years, scholars from a wide variety of disciplines have engaged in the study of urban religion. Taken together, these studies form a paradigm that intertwines (1) the politics of belonging, (2) regimes of space and territoriality, (3) materiality and sensorial power and (4) visibility. We argue that while scholars have conceptualised these aspects in very nuanced ways, there is a need to address in a more rigorous way immaterial dimensions of urban religion. We encapsulate these immaterial dimensions in the notion of ‘urban religious aspirations’, meaning the multiple ideational sources that underpin people’s religious investments in urban life. We illustrate the relevance of studying aspirations with an ethnographic example of two Hong Kong Christian women and their involvement in the Umbrella Movement. Exploring their narratives demonstrates the need to take immaterial aspects of religious life into account when researching urban religion, especially in contexts where the distinction between the religious and the secular is less clearly defined.     

Parent-child relationship, temperament, and physiological reactions to fear-inducing film clips: further evidence for differential susceptibility

Recent studies have supported the intriguing hypothesis that highly reactive infants are most susceptible to the effect of parenting. This study replicates and extends an earlier study on 4-year-olds concerning higher susceptibility of more fearful children to the quality of their relationships with their mothers, as shown by their physiological reactions to fear-inducing film clips. Two groups of children (4- and 7-year-olds) were shown the same fear-inducing and neutral film clips. During the film clips, their skin conductance and heart rate variability were measured. Both 4- and 7-year-olds responded to the fear-inducing film clips with increases in skin conductance and decreases in heart rate variability. A secure relationship affected the reactivity to fearful stimuli in temperamentally more fearful children but not in less fearful children irrespective of children's ages. Our findings add to the growing literature showing that children high in negative emotion are more susceptible to positive as well as negative rearing influences for better and for worse.     

Asymmetric frontal brain activity and parental rejection predict altruistic behavior: Moderation of oxytocin effects

Asymmetric frontal brain activity has been widely implicated in reactions to emotional stimuli and is thought to reflect individual differences in approach–withdrawal motivation. Here, we investigate whether asymmetric frontal activity, as a measure of approach–withdrawal motivation, also predicts charitable donations after a charity’s (emotion-eliciting) promotional video showing a child in need is viewed, in a sample of 47 young adult women. In addition, we explore possibilities for mediation and moderation, by asymmetric frontal activity, of the effects of intranasally administered oxytocin and parental love withdrawal on charitable donations. Greater relative left frontal activity was related to larger donations. In addition, we found evidence of moderation: Low levels of parental love withdrawal predicted larger donations in the oxytocin condition for participants showing greater relative right frontal activity. We suggest that when approach motivation is high (reflected in greater relative left frontal activity), individuals are generally inclined to take action upon seeing someone in need and, thus, to donate money to actively help out. Only when approach motivation is low (reflected in less relative left/greater relative right activity) do empathic concerns affected by oxytocin and experiences of love withdrawal play an important part in deciding about donations.     

Providing Ongoing Skill Development and Support for Educators and Parents of Students with Emotional and Behavioral Disabilities

Target six of the national agenda to improve outcomes for students with or at risk of emotional disturbance is reviewed. Having discussed this target with multiple stakeholders, the authors present four underlying themes that support ongoing skill development of providers and parents alike. These include building capacity of providers, decreasing isolation of school staff, gaining commitment of all school staff to support students with challenging behavior, and including parents and family members in staff development activities. The four underlying themes are discussed and recommendations given for ensuring ongoing skill development and support in education.     

Sensorimotor skills and language comprehension in autistic children

The objectives of this study were to examine the level of sensorimotor concepts of young autistic children and to relate these concepts to language comprehension. A sample of 16 autistic children with a mean mental age of 24.8 months was administered a standardized scale of sensorimotor intelligence and of receptive language. The autistic children demonstrated surprisingly sophisticated sensorimotor skills, particularly object permanence. While their initial performance was inferior to that of normal controls matched on mental age, particularly in their use of objects in combination, the difference between groups diminished on the second test administration. On the receptive language measure, the autistic children were less able to identify words correctly. The sensorimotor behavior of autistic children who demonstrated language comprehension did not differ from those who showed no language comprehension, except that the former group tended to use an object as an instrument somewhat more frequently. The fact that the autistic children were so impaired in language even with fairly good sensorimotor skills suggests that these skills, particularly object permanence, play a minor role in their language acquisition.Support for this research was provided by Biobehavioral Research Support Grant 516, Grant 12–41 from the March of Dimes, NIMH Postdoctoral Fellowship No. 1 F32 MH07550-01 (Ungerer), and NIMH Grant MH 33815-01. Subjects were recruited from the UCLA Research Center for the Study of Childhood Psychosis, funded by NIMH Grant MH 30897. We would like to thank members of the CRC, particularly Dr. Peter Tanguay, Dr. Barbara Fish, and Dr. B. J. Freeman, for their support of our research efforts.