全文获取类型
收费全文 | 6422篇 |
免费 | 413篇 |
国内免费 | 2篇 |
出版年
2023年 | 70篇 |
2022年 | 88篇 |
2021年 | 119篇 |
2020年 | 223篇 |
2019年 | 202篇 |
2018年 | 312篇 |
2017年 | 333篇 |
2016年 | 356篇 |
2015年 | 254篇 |
2014年 | 281篇 |
2013年 | 896篇 |
2012年 | 346篇 |
2011年 | 353篇 |
2010年 | 227篇 |
2009年 | 217篇 |
2008年 | 313篇 |
2007年 | 309篇 |
2006年 | 263篇 |
2005年 | 175篇 |
2004年 | 178篇 |
2003年 | 175篇 |
2002年 | 138篇 |
2001年 | 105篇 |
2000年 | 108篇 |
1999年 | 69篇 |
1998年 | 43篇 |
1997年 | 42篇 |
1996年 | 43篇 |
1995年 | 31篇 |
1994年 | 32篇 |
1993年 | 34篇 |
1992年 | 29篇 |
1991年 | 23篇 |
1990年 | 27篇 |
1989年 | 22篇 |
1988年 | 15篇 |
1987年 | 15篇 |
1986年 | 17篇 |
1984年 | 18篇 |
1983年 | 19篇 |
1982年 | 19篇 |
1981年 | 17篇 |
1980年 | 17篇 |
1979年 | 18篇 |
1978年 | 16篇 |
1977年 | 13篇 |
1975年 | 21篇 |
1972年 | 15篇 |
1971年 | 17篇 |
1970年 | 16篇 |
排序方式: 共有6837条查询结果,搜索用时 15 毫秒
221.
Cammarota M Bevilaqua LR Rossato JI Ramirez M Medina JH Izquierdo I 《Neurobiology of learning and memory》2005,84(1):25-32
Both the acquisition and the extinction of memories leave short- and long-term mnemonic traces. Here, we show that in male Wistar rats, the short-term memory for a step-down inhibitory avoidance task (IA) is resistant to extinction, and that its expression does not influence retrieval or extinction of long-term memory. It has been known for some time that short- and long-term inhibitory avoidance memory involve separate and parallel processes. Here we show that, instead, short-term extinction of IA long-term memory is the first step towards its long-term extinction, and that this link requires functional NMDA receptors and protein synthesis in the CA1 region of the dorsal hippocampus at the time of the first CS-no US presentation. 相似文献
222.
The transmission of tool use is a rare event in monkeys. Such an event arose in a group of semi-free-ranging Tonkean macaques (Macaca tonkeana) in which leaning a pole against the parks fence (branch leaning) appeared and spread to several males. This prompted us to test individual and social learning of this behavior in seven young males. In the first experiment, three males learned individually to obtain a food reward using a wooden pole as a climbing tool. They began using the pole to retrieve the reward only when they could alternatively experience acting on the object and reaching the target. In a second experiment, we first tested whether four other subjects could learn branch leaning after having observed a group-mate performing the task. Despite repeated opportunities to observe the demonstrator, they did not learn to use the pole as a tool. Hence we exposed the latter subjects to individual learning trials and they succeeded in the task. Tool use was not transmitted in the experimental situation, which contrasts with observations in the park. We can conclude that the subjects were not able to recognize the target as such. It is possible that they recognized it and learned the task individually when we alternated the opportunity to act upon the object and to reach the reward. This suggests that these macaques could then have associated the action they exercised upon the pole and the use of the pole as a means to reach the reward. 相似文献
223.
To investigate whether learning to discriminate between visual compound stimuli depends on decomposing them into constituting features, hens were first trained to discriminate four features (red, green, horizontal, vertical) from two dimensions (colour, line orientation). After acquisition, hens were trained with compound stimuli made up from these dimensions in two ways: a separable (line on a coloured background) stimulus and an integral one (coloured line). This compound training included a reversal of reinforcement of only one of the two dimensions (half-reversal). After having achieved the compound stimulus discrimination, a second dimensional training identical to the first was performed. Finally, in the second compound training the other dimension was reversed. Two major results were found: (1) an interaction between the dimension reversed and the type of compound stimulus: in compound training with colour reversal, separable compound stimuli were discriminated worse than integral compounds and vice versa in compound training with line orientation reversed. (2) Performance in the second compound training was worse than in the first one. The first result points to a similar mode of processing for separable and integral compounds, whereas the second result shows that the whole stimulus is psychologically superior to its constituting features. Experiment 2 repeated experiment 1 using line orientation stimuli of reversed line and background brightness. Nevertheless, the results were similar to experiment 1. Results are discussed in the framework of a configural exemplar theory of discrimination that assumes the representation of the whole stimulus situation combined with transfer based on a measure of overall similarity. 相似文献
224.
Knoppers BM 《The American journal of bioethics : AJOB》2005,5(2):33; discussion W3-33; discussion W4
225.
Recent findings are reviewed indicating that upper alpha oscillations - when analyzed with appropriate time/ frequency resolution - show a similar physiological reactivity as theta in working memory tasks. Comparable to theta, a load dependent increase in power can be observed during retention and increased evoked activity during retrieval. During retrieval attempts theta behaves like a traveling wave spreading from anterior to posterior sites. During actual retrieval, however, evoked upper alpha becomes transiently nested in theta. We suggest that theta reflects working memory functions whereas upper alpha may be important for the reactivation of long-term memory codes in short-term memory. 相似文献
226.
Most research on the rapid mental processes of on-line language processing has been limited to the study of idealized, fluent utterances. Yet speakers are often disfluent, for example, saying "thee, uh, candle" instead of "the candle." By monitoring listeners' eye movements to objects in a display, we demonstrated that the fluency of an article ("thee uh" vs. "the") affects how listeners interpret the following noun. With a fluent article, listeners were biased toward an object that had been mentioned previously, but with a disfluent article, they were biased toward an object that had not been mentioned. These biases were apparent as early as lexical information became available, showing that disfluency affects the basic processes of decoding linguistic input. 相似文献
227.
Calcium signaling in mitral cell dendrites of olfactory bulbs of neonatal rats and mice during olfactory nerve Stimulation and beta-adrenoceptor activation
下载免费PDF全文
![点击此处可从《Learning & memory (Cold Spring Harbor, N.Y.)》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Yuan Q Mutoh H Debarbieux F Knöpfel T 《Learning & memory (Cold Spring Harbor, N.Y.)》2004,11(4):406-411
Synapses formed by the olfactory nerve (ON) provide the source of excitatory synaptic input onto mitral cells (MC) in the olfactory bulb. These synapses, which relay odor-specific inputs, are confined to the distally tufted single primary dendrites of MCs, the first stage of central olfactory processing. beta-adrenergic modulation of electrical and chemical signaling at these synapses may be involved in early odor preference learning. To investigate this possibility, we combined electrophysiological recordings with calcium imaging in olfactory bulb slices prepared from neonatal rats and mice. Activation of ON-MC synapses induced postsynaptic potentials, which were associated with large postsynaptic calcium transients. Neither electrical nor calcium responses were affected by beta-adrenergic agonists or antagonist. Immunocytochemical analysis of MCs and their tufted dendrites revealed clear immunoreactivity with antibodies against alpha1A (Cav2.1, P/Q-type) and alpha1B (Cav2.2, N-type), but not against alpha1C (Cav1.2, L-type) or alpha1D (Cav1.3, L-type) calcium channel subunits. Moreover, nimodipine, a blocker of L-type calcium channels, had no effect on either electrical or calcium signaling at ON-MC synapses. In contrast to previous evidence, we concluded that in neonatal rats and mice (P5-P8), mitral cells do not express significant amounts of L-type calcium channels, the calcium channel type that is often targeted by beta-adrenergic modulation. The absence of beta-adrenergic modulation on either electrical or calcium signaling at ON-MC synapses of neonatal rats and mice excludes the involvement of this mechanism in early odor preference learning. 相似文献
228.
The sensorimotor transformations necessary for generating appropriate motor commands depend on both current and previously acquired sensory information. To investigate the relative impact (or weighting) of visual and haptic information about object size during grasping movements, we let normal subjects perform a task in which, unbeknownst to the subjects, the object seen (visual object) and the object grasped (haptic object) were never the same physically. When the haptic object abruptly became larger or smaller than the visual object, subjects in the following trials automatically adapted their maximum grip aperture when reaching for the object. This adaptation was not dependent on conscious processes. We analyzed how visual and haptic information were weighted during the course of sensorimotor adaptation. The adaptation process was quicker and relied more on haptic information when the haptic objects increased in size than when they decreased in size. As such, sensory weighting seemed to be molded to avoid prehension error. We conclude from these results that the impact of a specific source of sensory information on the sensorimotor transformation is regulated to satisfy task requirements. 相似文献
229.
Schulz D Topic B De Souza Silva MA Huston JP 《Neurobiology of learning and memory》2004,82(2):128-141
Extinction of escape behavior in the water maze due to the removal of the platform, was hypothesized to induce a negative state, including the development of immobility, which is held to reflect a state of "despair" when measured in the forced swimming test. 27 aged and 8 adult animals (26 and 3 months old Wistar rats, respectively) were tested in the water maze during nine days with a platform hidden, followed by 7 days of extinction trials with the platform absent. As expected, both age groups developed immobility over the extinction trials, with the aged showing more than the adults. To examine whether the age difference in immobility was related to performance differences during acquisition, the aged were subdivided into superior, intermediate and inferior learners (n = 9 per group) on the basis of overall times to platform during acquisition, and compared with each other and the adults. Results showed that the aged inferior learners displayed the highest levels of immobility among the aged. Immobility scores were then correlated with post-mortem neurotransmitter contents in the hippocampus and ventral striatum. In the ventral striatum, levels of immobility were correlated with levels of acetylcholine, dopamine and the metabolite dihydroxyphenylacetic acid in the aged, and with norepinephrine in the adults. The data support the hypothesis that multiple extinction trials in the water maze result in immobility that may indicate "behavioral despair," and that striatal neurotransmitter systems correlate with the degree of its expression. The concept of extinction-induced despair is held to provide the promise of a conceptual and empirical model of human depression that is the consequence of loss of reinforcers. 相似文献
230.
Bellissimo MI Kouzmine I Ferro MM de Oliveira BH Canteras NS Da Cunha C 《Neurobiology of learning and memory》2004,82(2):150-158
Adult male Wistar rats with a substantia nigra pars compacta (SNc) lesion induced by intranigral administration of 1 micromol 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) were used as a model of early phase Parkinson's disease (PD). This lesion caused a partial depletion of striatal dopamine (DA). The animals were submitted to a spatial working memory version of the water maze task in which they had to find a hidden (submersed) platform using online-maintained information that the platform remains in the same place during four consecutive trials, but that it is moved to another place every training day. Left, but not right SNc-lesioned rats were impaired in finding the platform in the second trial. This result suggests that the left SNc plays a key role in spatial working memory. Control experiments ruled out the possibility that motor impairment, sensory neglect, and/or impairment in the mental representation of the contralateral spatial environment had affected performance of the SNc-lesioned rats. 相似文献