PHILOSOPHICAL QUESTIONS AND BIOLOGICAL FINDINGS,PART I: HUMAN COOPERATIVITY,COMPETITION, AND AGGRESSION

This Part II of a two-part article illustrates how research in evolutionary biology, anthropology, archeology, and psychology illuminates questions arising in philosophy—specifically questions about René Girard's theory of aggression. Part I looked at: (i) how old the systemic practice of severe aggression is; (ii) how much of it results from humanity's mimetic/social and competitive nature and how much from ecological, resource, and cultural conditions; and (iii) if ecological, resource, and cultural conditions are important, might we adapt this information toward greater cooperativity today? Part II investigates Girard's theory of ritual sacrifice—especially human sacrifice—as a societal steam valve for the systemic aggression explored in Part I. It draws on theories of play, theater, and art to examine the role and function of such ritual sacrifice.     

Removal of S6K1 and S6K2 leads to divergent alterations in learning, memory, and synaptic plasticity

Protein synthesis is required for the expression of enduring memories and long-lasting synaptic plasticity. During cellular proliferation and growth, S6 kinases (S6Ks) are activated and coordinate the synthesis of de novo proteins. We hypothesized that protein synthesis mediated by S6Ks is critical for the manifestation of learning, memory, and synaptic plasticity. We have tested this hypothesis with genetically engineered mice deficient for either S6K1 or S6K2. We have found that S6K1-deficient mice express an early-onset contextual fear memory deficit within one hour of training, a deficit in conditioned taste aversion (CTA), impaired Morris water maze acquisition, and hypoactive exploratory behavior. In contrast, S6K2-deficient mice exhibit decreased contextual fear memory seven days after training, a reduction in latent inhibition of CTA, and normal spatial learning in the Morris water maze. Surprisingly, neither S6K1- nor S6K2-deficient mice exhibited alterations in protein synthesis-dependent late-phase long-term potentiation (L-LTP). However, removal of S6K1, but not S6K2, compromised early-phase LTP expression. Furthermore, we observed that S6K1-deficient mice have elevated basal levels of Akt phosphorylation, which is further elevated following induction of L-LTP. Taken together, our findings demonstrate that removal of S6K1 leads to a distinct array of behavioral and synaptic plasticity phenotypes that are not mirrored by the removal of S6K2. Our observations suggest that neither gene by itself is required for L-LTP but instead may be required for other types of synaptic plasticity required for cognitive processing.     

Biblical and Theological Perspectives on Children,Parents, and ‘Best Practices' for Faith Formation: Resources for Child,Youth, and Family Ministry Today

Abstract : One of the most important ways to strengthen the faith formation of children and young people, and child, youth, and family ministries is by engaging and supporting parents or primary care‐givers. This article seeks to address this challenge by mining resources from the Bible and Christian theology about the roles and responsibilities of parents, the complexity and dignity of children, and ways to pass on the faith. By taking into account theological perspectives on parents, children, and faith formation, church leaders can better engage both children and parents, and they can strengthen all areas of their work with or on behalf of children and young people, whether in children's ministry, youth and family ministry, religious education, or child advocacy.     

Reading First kindergarten classroom instruction and students' growth in phonological awareness and letter naming–decoding fluency

This study investigated the role of the amount, content, and implementation of reading instruction provided by 17 kindergarten teachers in eight Reading First elementary schools as it related to students' progress (n = 286 students) on early reading assessments of phonological awareness and letter naming–decoding fluency. Children's phonological awareness and letter naming–decoding fluency grew significantly from fall to spring. On average, across the three 60 min observations, teachers provided over 30 min a day of phonological awareness and phonics instruction and 15 min a day of vocabulary and comprehension instruction. Global ratings of instructional quality revealed two implementation factors: explicit and individualized implementation and meaningful interactions around text. Hierarchical linear modeling revealed that the amounts of specific instructional content, as well as how this instruction was implemented, was related to students' letter knowledge and phonological awareness skill growth.     

An automated apparatus for presenting depth-rotated three-dimensional objects in human and animal object recognition research

For practical reasons, research on the recognition of objects from different viewpoints has relied almost exclusively on the use of two-dimensional representations of three-dimensional objects. We describe an apparatus that enables the presentation of three-dimensional objects in a discrimination learning paradigm. Three chambers positioned on a movable table allow each of two objects to be presented on either the left or the right side; a viewing window exposes only two of the objects at a time. The objects can be arbitrarily designated as either an S+ or an S−. In addition, they can be placed precisely in any arbitrary Startposition and rotated in depth in 100 steps of 3.6° each. We have successfully used this apparatus to investigate recognition of depth-rotated objects by both pigeons and humans. By varying the stimuli, number of stimulus chambers, and software programs, the apparatus can be used for other types of tasks and to investigate other types of processes.     

Discussion

Robert Fudge, Problems with Contextualizing Aesthetic Properties , p67
Marcia Muelder Eaton, Response to Robert Fudge , p70     

Identification of emotional expressiveness in facial photographs over 36 h of extended vigilance in healthy young men—a preliminary study

Changes in sleep patterns negatively influence some emotional responses, but their effects on facial expressiveness identification are unclear. To investigate these effects, 21 young, healthy, male volunteers of intermediate chronotype evaluated emotional expressiveness of faces depicting 6 basic emotions in 5 emotional gradients every 4?h over 36?h of continuous wakefulness. To measure attention and mood we used the Psychomotor Vigilance test and the Positive and Negative Affect Schedule Expanded, respectively. We found effects of emotional gradient for all types of emotions (100%?>?80%?>?60%?>?40%?>?20%) during all tested periods, with no indications of circadian effects. The only emotional rating to be affected was disgust, which was progressively blunted throughout the experiment. This effect did not parallel homeostatic and circadian changes in mood, alertness or attention. We conclude that identifying disgust on facial photographs is particularly sensitive to lack of sleep irrespective of sleep-induced changes in mood and attention in males.     

Validation of a telephone screening test for Alzheimer's disease

Financial constraints, mobility issues, medical conditions, crime in local areas can make cognitive assessment difficult for elders and telephone interviews can be a good alternative. This study was carried out to evaluate the reliability, validity and clinical utility of a Brazilian telephone version of the Mini Mental State Examination (Braztel-MMSE) in a community sample of healthy elderly participants and AD patients. The MMSE and the Braztel-MMSE were applied to 66 AD patients and 67 healthy elderly participants. The test-retest reliability was strong and significant (r = .92, p = .01), and the correlation between the Braztel-MMSE and the MMSE were significant (p = .01) and strong (r = .92). The general screening ability of the Braztel-MMSE was high (AUC = 0.982; CI95% = 0.964-1.001). This telephone version can therefore be used as a screening measure for dementia in older adults that need neuropsychological screening and cannot present for an evaluation.     

Changes in auditory frequency guide visual-spatial attention

How do the characteristics of sounds influence the allocation of visual–spatial attention? Natural sounds typically change in frequency. Here we demonstrate that the direction of frequency change guides visual–spatial attention more strongly than the average or ending frequency, and provide evidence suggesting that this cross-modal effect may be mediated by perceptual experience. We used a Go/No-Go color-matching task to avoid response compatibility confounds. Participants performed the task either with their heads upright or tilted by 90°, misaligning the head-centered and environmental axes. The first of two colored circles was presented at fixation and the second was presented in one of four surrounding positions in a cardinal or diagonal direction. Either an ascending or descending auditory-frequency sweep was presented coincident with the first circle. Participants were instructed to respond to the color match between the two circles and to ignore the uninformative sounds. Ascending frequency sweeps facilitated performance (response time and/or sensitivity) when the second circle was presented at the cardinal top position and descending sweeps facilitated performance when the second circle was presented at the cardinal bottom position; there were no effects of the average or ending frequency. The sweeps had no effects when circles were presented at diagonal locations, and head tilt entirely eliminated the effect. Thus, visual–spatial cueing by pitch change is narrowly tuned to vertical directions and dominates any effect of average or ending frequency. Because this cross-modal cueing is dependent on the alignment of head-centered and environmental axes, it may develop through associative learning during waking upright experience.