A Comparison of MMPI-2 Profiles Between Parental Alienation Cases and Custody Cases

Journal of Child and Family Studies - The present study aimed at understanding the personality features of mothers and fathers engaged in parental alienation—a family dynamic in which one...     

The Default Mode Network and Recurrent Depression: A Neurobiological Model of Cognitive Risk Factors

A neurobiological account of cognitive vulnerability for recurrent depression is presented based on recent developments of resting state neural networks. We propose that alterations in the interplay between task positive (TP) and task negative (TN) elements of the Default Mode Network (DMN) act as a neurobiological risk factor for recurrent depression mediated by cognitive mechanisms. In the framework, depression is characterized by an imbalance between TN-TP components leading to an overpowering of TP by TN activity. The TN-TP imbalance is associated with a dysfunctional internally-focused cognitive style as well as a failure to attenuate TN activity in the transition from rest to task. Thus we propose the TN-TP imbalance as overarching neural mechanism involved in crucial cognitive risk factors for recurrent depression, namely rumination, impaired attentional control, and cognitive reactivity. During remission the TN-TP imbalance persists predisposing to vulnerability of recurrent depression. Empirical data to support this model is reviewed. Finally, we specify how this framework can guide future research efforts.     

Complete recovery of olfactory associative learning by activation of 5-HT4 receptors after dentate granule cell damage in rats

Bilateral intradentate injections of 3.0 μg of colchicine induced a substantial loss of granule cells and damage to the overlying pyramidal cell layer in region CA1 in adult male Long-Evans rats. All rats with such lesions showed a significant associative learning deficit in an olfactory discrimination task, while being unimpaired in the procedural component of this task. Injection of a partial selective 5-HT₄ agonist (SL65.0155; 0.01 mg/kg, i.p., vs. saline) before the third of six training sessions enabled complete recovery of associative learning performance in the lesioned rats. Activation of 5-HT₄ receptors by a selective agonist such as SL65.0155 might therefore provide an opportunity to reduce learning and memory deficits associated with temporal lobe damage, and could be useful for the symptomatic treatment of memory dysfunctions related to pathological aging such as Alzheimer’s disease.     

Cognition in action: testing a model of limb apraxia

Assessment of limb apraxia is still suffering from Liepmann's legacy and performance in gesture-processing tests is generally rendered by classifying patients' profile according to the classic clinical labels of ideomotor and ideational apraxia. At odds with other cognitive functions, interpretation of apraxia has suffered from a lack of a reliable model which does justice to its complexity. Recently such a model has been proposed (Rothi et al., 1991, 1997). In this article a modified version of this model is presented and predictions are made according to its functional architecture. Five different patterns of impairment of gesture processing are postulated. To validate the predicted performance profiles, 19 left-hemisphere-damaged patients were assessed by means of an ad hoc battery of four praxis tests. Four of the five predicted apraxia patterns were observed, the fifth being more equivocal. These results support the need to overcome the simplistic dichotomous view of apraxia and confirm the fruitfulness of a model of normal gesture processing in order to understand dissociations in apraxia.     

Shaping our personal past: Assessing the phenomenology of autobiographical memory and its association with object and spatial imagery

A new instrument has been developed that allows a comprehensive assessment of the relevant dimensions of the phenomenology of autobiographical memories (Assessment of the Phenomenology of Autobiographical Memory, APAM), and their association with visual object and spatial imagery has been examined. An initial version of APAM consisting of 30 items (the first 28 measured on a seven-point Likert-type scale) was developed and administered to a sample of 138 undergraduates. To test whether each item consistently measured the same dimension across different memories, all questions were rated for 12 cues. Results showed that 25 Likert-type items possessed adequate levels of internal consistency and unidimensionality across cues. We also found that higher levels of visual object imagery were associated with more sensory details and recollective qualities of memory, and with stronger experience of sensory and emotional reliving. The theoretical and practical usefulness of APAM as well as the relevance of visual object imagery in the phenomenology of autobiographical memory are discussed.     

Identification,localization, and “iconic memory”: An evaluation of the bar-probe task

The partial report tachistoscopic task has been used to define “iconic memory,” a labile image-like precategorical visual store. Six interrelated partial report studies are reported that challenge the construct. On each trial, subjects were shown an eight-letter pseudoword (representing one of four orders of approximation to English) and a bar probe indicating which letter to report. The probe was delayed systematically, and the experiments included both mask and no-mask conditions. All three variables-familiarity of the material, masking, and delay of the probe-affected accuracy of report. Delaying the probe, for example, reduced accuracy by increasing location errors. Delaying the mask increased accuracy by reducing both location and item errors, but it did not reduce the location errors until its effect on item errors had reached asymptote. Across the stimulus array, however, masking reduced accuracy at all delays by increasing location errors. Finally, the greater accuracy associated with higher orders of approximation to English was complemented by a decrease in item errors, but the familiarity factor had no effect on location errors. Taken together, even though the task has been used to define the idea, the results indicate that the bar-probe task cannot be explained in terms of a simple iconic memory concept. Instead of a simple image-like buffer, the explanation requires a feature buffer, an “intelligent” letter identification process, and a postidentification character buffer. Iconic memory is a construct that oversimplifies the information processing system used in the bar-probe task.     

The clock as a focus of selective attention in those with primary insomnia: An experimental study using a modified Posner paradigm

Espie and colleagues [(2006). The attention-intention-effort pathway in the development of psychophysiological insomnia: a theoretical review. Sleep Medicine Reviews, 10, 215-245] propose a route into psychophysiological insomnia along the attention-intention-effort pathway which focuses on the inhibition of sleep-wake automaticity. A contributing factor to this is selective attention to sleep (alongside explicit intention to sleep and effort in the sleep engagement process). Following on from previous work on selective attention to sleep [Marchetti, L. M., Biello, S. M., Broomfield, N. M., MacMahon, K. M. A., & Espie, C. A. (2006). Who is pre-occupied with sleep?. A comparison of attention bias in people with psychphysiological insomnia, delayed sleep phase syndrome and good sleepers using the induced change blindness paradigm. Journal of Sleep Research, 15, 212-221; MacMahon, K., Broomfield, N., Macphee, L., & Espie, C. A. (2006). Attention bias for sleep related stimuli in primary insomnia and delayed sleep phase syndrome using the dot-probe task. Sleep, 29, 11] and considering the importance of monitoring both internal and external cues in the maintenance of insomnia, as highlighted in the cognitive model of insomnia [Harvey, A. G. (2002). A cognitive model of insomnia. Behaviour Research and Therapy, 40, 869-893], a cognitive probe task was employed to investigate further the role of the clock as a focus of selective attention in those with primary insomnia.A 2 × 2 between participants design comparing reaction time of individuals with primary insomnia (n = 22) and normal sleepers (n = 22) on a modified Posner paradigm. Responses obtained from a computer task presenting times which fall within a normal sleep period were analysed.Individuals with primary insomnia demonstrated delayed disengagement to the clock (F(1,84) = 6.9, p < 0.05) which is taken as further support for previous research demonstrating that individuals with primary insomnia exhibit an attentional bias to sleep related stimuli.These results lend support to the attention-intention-effort model (Espie et al., 2006) and the cognitive model (Harvey, 2002) both of which recognise the importance of selective attention towards salient stimuli in the maintenance of insomnia. Possible clinical implications of attentional bias to sleep as a marker of psychopathology progression and treatment efficacy are discussed.