Suppes Predicates for Meta-Ranking Structures

In this paper the general notion of Bourbaki structures, interpreted in terms of Suppes predicates, will be used to axiomatize a system of meta-rankings in the sense introduced by A. K. Sen. It will be argued that this axiomatization must take place in a Kantian-ruled world in order to provide a link between meta-rankings and individual actions.Dedicated to Prof. Francisco A. Doria on his 50th birthday.     

Non-Commutative Topology and Quantales

The relationship between q-spaces (c.f. [9]) and quantum spaces (c.f. [5]) is studied, proving that both models coincide in the case of Spec A, the spectrum of a non-commutative C*-algebra A. It is shown that a sober T ₁ quantum space is a classical topological space. This difficulty is circumvented through a new definition of point in a quantale. With this new definition, it is proved that Lid A has enough points. A notion of orthogonality in quantum spaces is introduced, which permits us to express the usual topological properties of separation. The notion of stalks of sheaves over quantales is introduced, and some results in categorial model theory are obtained.     

Bilateral opercular syndrome and crossed aphemia due to a right insular lesion: A clinicopathological study

A right-handed male patient suddenly noted lower bilateral facial and lingual palsy, and inability to masticate and swallow, but with preserved automatic functions. He was mute, communicating only through writing, but verbal comprehension was normal (aphemia). On anatomopathological examination, an ischemic infarction of the entire right insula, with mild extension to the fronto-temporoparietal operculum was observed. The left hemisphere was normal. The clinical findings suggest a bilateral opercular syndrome due to a right hemisphere lesion and a crossed aphemia.     

Pre-training to find a hidden platform in the Morris water maze can compensate for a deficit to find a cued platform in a rat model of Parkinson's disease

The bilateral intranigral infusion of 1 micromol 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in adult male Wistar rats caused a specific and partial loss of substantia nigra pars compacta (SNc) dopamine neurons, a partial depletion of striatal dopamine, and a deficit to learn the intra-maze cued version of the Morris water maze. Pre-training the SNc rats in the spatial version of the water maze or simply maintaining the animals on the water maze platform reversed this deficit. This improvement was even observed when the order of the extra-maze cues presented to the rats during pre-training of the spatial version was changed during training of the intra-maze cued version. However, this deficit was not reversed either by maintaining the animals on the platform if the spatial cues were surrounded and covered with a curtain or by swimming sessions in the maze without the escape platform and the curtain. These findings suggest that none of the following elements alone, learned during the spatial task pre-training, could help SNc rats learn the intra-maze cued task: improvement of swimming skills or knowledge of the existence of the escape platform; distance between the platform and the border of the pool; location of a particular extra-maze cue; relations among extra-maze cues. However, the simultaneous presence of the escape platform and extra-maze cues (irrespective of their relational configuration) during the pre-training sessions proved to be necessary for this improving effect to occur.     

Amnesic effect of GMP depends on its conversion to guanosine

Extracellular guanine-based purines, namely the nucleotides GTP, GDP, GMP and the nucleoside guanosine, exert important neuroprotective and neuromodulator roles in the central nervous system, which may be related to inhibition of the glutamatergic neurotransmission activity. In this study, we investigated GMP effects on mice inhibitory avoidance performance and the dependence on its conversion to guanosine for such effect, by using the ecto-5'-nucleotidase specific inhibitor AOPCP. We also investigated if this conversion occurs in the central nervous system or peripherally, and if guanosine and GMP affect nociception by the tail-flick test. I.p. GMP or guanosine (7.5 mg/kg) or i.c.v. GMP (480 nmol) pretraining administration was amnesic for the inhibitory avoidance task. I.c.v. AOPCP (1 nmol) administration completely reversed the amnesic effect of i.c.v. GMP, but not of i.p. GMP, indicating that peripheral conversion of GMP to guanosine is probably relevant to this effect. AOPCP alone did not interfere with the performance. Furthermore, tail-flick measurement was unaffected by i.p. GMP and guanosine, suggesting that the amnesic effect of both purines was not due to some antinociceptive effect against the footshock used in the task. All these data together, in accordance to those previously observed in studies involving glutamate uptake and seizures reinforce the idea that guanosine is the specific extracellular guanine-based purines effector and indicate that its conversion occurs not only in the central nervous system but also peripherally.     

Stratified Belief Bases Revision with Argumentative Inference

We propose a revision operator on a stratified belief base, i.e., a belief base that stores beliefs in different strata corresponding to the value an agent assigns to these beliefs. Furthermore, the operator will be defined as to perform the revision in such a way that information is never lost upon revision but stored in a stratum or layer containing information perceived as having a lower value. In this manner, if the revision of one layer leads to the rejection of some information to maintain consistency, instead of being withdrawn it will be kept and introduced in a different layer with lower value. Throughout this development we will follow the principle of minimal change, being one of the important principles proposed in belief change theory, particularly emphasized in the AGM model. Regarding the reasoning part from the stratified belief base, the agent will obtain the inferences using an argumentative formalism. Thus, the argumentation framework will decide which information prevails when sentences of different layers are used for entailing conflicting beliefs. We will also illustrate how inferences are changed and how the status of arguments can be modified after a revision process.