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41.
Marcello Ienca Tenzin Wangmo Fabrice Jotterand Reto W. Kressig Bernice Elger 《Science and engineering ethics》2018,24(4):1035-1055
The use of Intelligent Assistive Technology (IAT) in dementia care opens the prospects of reducing the global burden of dementia and enabling novel opportunities to improve the lives of dementia patients. However, with current adoption rates being reportedly low, the potential of IATs might remain under-expressed as long as the reasons for suboptimal adoption remain unaddressed. Among these, ethical and social considerations are critical. This article reviews the spectrum of IATs for dementia and investigates the prevalence of ethical considerations in the design of current IATs. Our screening shows that a significant portion of current IATs is designed in the absence of explicit ethical considerations. These results suggest that the lack of ethical consideration might be a codeterminant of current structural limitations in the translation of IATs from designing labs to bedside. Based on these data, we call for a coordinated effort to proactively incorporate ethical considerations early in the design and development of new products. 相似文献
42.
In the present study, we investigated, using language, which motor information is automatically activated by observing 3-D objects (i.e., manipulation vs. function) and whether this information is modulated by the objects' location in space. Participants were shown 3-D pictures of objects located in peripersonal versus extrapersonal space. Immediately after, they were presented with function, manipulation, or observation verbs (e.g., "to drink," "to grasp," "to look at") and were required to judge whether the verb was compatible with the presented object. We found that participants were slower with observation verbs than with manipulation and function verbs. With both function and manipulation verbs, participants were faster when objects were presented in reachable space. Interestingly, the fastest response times were recorded when participants read function verbs while objects were presented in the accessible space. Results suggest that artifacts are first conceived in terms of affordances linked to manipulation and use, and that affordances are differently activated, depending on context. 相似文献
43.
Pace-Schott EF Shepherd E Spencer RM Marcello M Tucker M Propper RE Stickgold R 《Neurobiology of learning and memory》2011,95(1):24-36
The effects of a daytime nap on inter-session habituation to aversive visual stimuli were investigated. Healthy young adult volunteers viewed repeated presentations of highly negative and emotionally neutral (but equally arousing) International Affective Picture System (IAPS) photographs during two afternoon sessions separated by 2.5h. Half of the photographs were shown at both sessions (Repeated Sets) and half differed between sessions (Novel Sets). For each stimulus presentation, evoked skin conductance response (SCR), heart-rate deceleration (HRD) and corrugator supercilii EMG response (EMG), were computed and range corrected using respective maximum session-1 responses. Following each presentation, subjects rated each photograph on dimensions of pleasantness and arousability. During the inter-session interval, Nap subjects had a 120-min polysomnographically monitored sleep opportunity, whereas Wake subjects watched a non-stimulating video. Nap and Wake subjects did not differ in their subjective ratings of photographs. However, for Repeated-Set photographs, Nap subjects demonstrated greater inter-session habituation in SCR and EMG but a trend toward lesser inter-session habituation in HRD. These group differences were absent for Novel-Set photographs. Group differences across all measures were greater for negative stimuli. Occurrence of SWS during the nap was associated with greater inter-session habituation of EMG whereas occurrence of REM was associated with lesser inter-session habituation of SCR to negative stimuli. Sleep may therefore promote emotional adjustment at the level of somatic responses. Physiological but not subjective inter-session habituation to aversive images was enhanced by a daytime nap. 相似文献
44.
45.
Glucocorticoid administration into the dorsal striatum [corrected] facilitates memory consolidation of inhibitory avoidance training but not of the context or footshock components 下载免费PDF全文
Medina AC Charles JR Espinoza-González V Sánchez-Resendis O Prado-Alcalá RA Roozendaal B Quirarte GL 《Learning & memory (Cold Spring Harbor, N.Y.)》2007,14(10):673-677
It is well established that glucocorticoid administration into a variety of brain regions facilitates memory consolidation of fear-conditioning tasks, including inhibitory avoidance. The present findings indicate that the natural glucocorticoid corticosterone administered into the dorsal striatum (i.e., caudate nucleus) of male Wistar rats produced dose- and time-dependent enhancement of inhibitory avoidance memory consolidation. However, as assessed with a modified inhibitory avoidance procedure that took place on two sequential days to separate context training from footshock training, corticosterone administration into the dorsal striatum did not enhance memory of either the contextual or aversively motivational aspects of the task. 相似文献
46.
Martínez MP Sánchez AI Miró E Medina A Lami MJ 《Journal of clinical psychology in medical settings》2011,18(4):380-391
This study examined the relationship between several cognitive-affective factors of the fear-avoidance model of pain, the
big five model of personality, and functional impairment in fibromyalgia (FM). Seventy-four FM patients completed the NEO Five-Factor Inventory, the Pain Catastrophizing Scale, the Pain Anxiety Symptoms Scale-20, the Pain Vigilance
and
Awareness Questionnaire, and the Impairment and Functioning Inventory. Results indicated that the cognitive-affective factors of pain are differentially associated with personality traits. Neuroticism
and conscientiousness were significant predictors of pain catastrophizing, and neuroticism, openness, and agreeableness were
significant predictors of pain anxiety. Personality traits did not contribute significantly to vigilance to pain. The effect
of neuroticism upon pain anxiety was mediated by pain catastrophizing, and neuroticism showed a trend to moderate the relationship
between impairment and pain anxiety. Results support the fear-avoidance model of pain. Implications of the findings for the
understanding and management of FM are discussed. 相似文献
47.
Rats were trained in a one-trial step-down inhibitory avoidance task at the age of 3 months and tested for retention 1 day later, or 3, 6, 9, 12, 15, and 19 months later, i.e., when the animals were 3, 6, 9, 12, 15, 18, or 22 months of age. Retrieval performance declined with time and was undetectable in the last two age groups. Exposure to an unrelated novel environment (a square box lined with black plastic) 1 h before retention testing enhanced retrieval at all ages, regardless of the decline in the level of test session performance. The effect cannot be explained by an anxiogenic effect of the novelty box, or by an influence of novelty on locomotion or exploration, or by a nonspecific influence of exposure to novelty on step-down latency in the inhibitory avoidance apparatus. 相似文献
48.
In a sample of 82 undergraduates, the personality dimension of novelty seeking, which has been hypothesized to be influenced by levels of dopamine in the central nervous system, was associated with attitudes regarding money. 相似文献
49.
In a sample of 138 college students, the personal finance behaviors of impulse control and organization were negatively associated with the use of recreational drugs and with scores on measures of depression, mania, and anxiety. 相似文献
50.
We determined visual reaction times to monocular and binocular changes in the luminance of isochromatic stimuli and to monocular and binocular changes in the color of isoluminant stimuli. Two isoluminant color changes were tested: chromatic variations along the red-green axis of Boynton's (1986) two-stage color vision model and chromatic variations along the yellow-blue axis of the same model. The results indicate a greater degree of binocular summation for luminance change than for color change. This result was largely independent of the motor component of reaction time. 相似文献