Toilet training for a young boy with pervasive developmental disorder

We employed a variation of the Azrin–Foxx ( 1971 ) procedure with a 3.5‐year‐old boy diagnosed with Pervasive Developmental Disability (PDD). Unique features of our design included tailoring to the in‐home environment, training without systematically increasing fluid intake, introduction under circumstances that facilitated generalization and transfer without special procedures, the elimination of some specialized equipment, and use of social and activity reinforcers. Training was successful and was reported to have generalized to the inclusive school environment. Copyright © 2004 John Wiley & Sons, Ltd.     

Consequences of regret aversion in real life: The case of the Dutch postcode lottery

Although ample research has shown that decisions may cause regret and that the anticipation of regret may influence decision-making, this previous research was largely limited to hypothetical choices with student participants. The current research replicates and extends these findings for real life lottery participation decisions in non-student samples. Four studies are reported in which two lotteries in the Netherlands, the Postcode Lottery and the National State Lottery, were compared. The State Lottery is a traditional lottery in which one has to buy a ticket with a number printed on it. In the Postcode Lottery, one’s postcode is the ticket number, and hence even if not participating one may still find out that one would have won had one played. As our research shows, this particular feedback that is present in the Postcode Lottery but absent in the State Lottery influences the level of anticipated post-decisional regret, and moderates the influence that anticipated regret has on lottery participation. Study 1, 100 street interviews, confirmed our expectations that the Postcode Lottery may elicit regret. Study 2 found under controlled conditions, that people anticipate more regret over not playing when there is feedback about the neighbors winning a prize in the Postcode Lottery than in the State Lottery. However, when this feedback is absent they anticipate equal amounts of regret over not playing. Study 3 replicated these findings for regret, while showing that the two lotteries do not differ with respect to envy and jealousy, emotions that might also be invoked in this context. Study 4 validated that, as we predicted, anticipations of post-decisional regret influence decisions to play the Postcode lottery, but not the State Lottery. These findings demonstrate the external and discriminant validity of anticipated regret for decision-making, and indicate its pragmatic relevance. The implications or recent developments in regret research are discussed.     

Regret in Decision Making

Decision research has only recently started to take seriously the role of emotions in choices and decisions. Regret is the emotion that has received the most attention. In this article, we sample a number of the initial regret studies from psychology and economics, and trace some of the complexities and contradictions to which they led. We then sketch a new theory, decision justification theory (DJT), which synthesizes several apparently conflicting findings. DJT postulates two core components of decision–related regret, one associated with the (comparative) evaluation of the outcome, the other with the feeling of self–blame for having made a poor choice. We reinterpret several existing studies in DJT terms. We then report some new studies that directly tested (and support) DJT, and propose a number of research issues that follow from this new approach to regret.     

Busy doing nothing: Evidence for nonaction-effect binding

Research on voluntary action has focused on the question of how we represent our behavior on a motor and cognitive level. However, the question of how we represent voluntary not acting has been completely neglected. The aim of the present study was to investigate the cognitive and motor representation of intentionally not acting. By using an action-effect binding approach, we demonstrate similarities of action and nonaction. In particular, our results reveal that voluntary nonactions can be bound to an effect tone. This finding suggests that effect binding is not restricted to an association between a motor representation and a successive effect (action-effect binding) but can also occur for an intended nonaction and its effect (nonaction-effect binding). Moreover, we demonstrate that nonactions have to be initiated voluntarily in order to elicit nonaction-effect binding.     

Catechol-O-methyltransferase Val158Met genotype affects neural correlates of aversive stimuli processing

It was previously shown that variation of the catechol-O-methyltransferase (COMT) gene modulates brain activity during the processing of stimuli with negative valence, but not for pleasant stimuli. Here, we tested whether the COMT genotype also modulates the electrophysiological correlates of emotional processing and explored whether the environmental factor of life stress influences this effect. Using the early posterior negativity (EPN) paradigm, event-related brain potentials were measured in 81 healthy individuals during the processing of pictures that evoked emotions of positive and negative valence. As was hypothesized, the COMT genotype affected the EPN amplitudes for unpleasant stimuli, but not for pleasant ones. Specifically, Met/Met carriers respond more sensitively to unpleasant stimuli, as compared with Val/Val carriers. We did not find evidence that life stress moderates the effect of the COMT genotype on emotional stimuli processing.     

Regulating Human Participants Protection in Medical Research and the Accreditation of Medical Research Ethics Committees in the Netherlands

The review system on research with human participants in the Netherlands is characterised as a decentralised controlled and integrated peer review system. It consists of an independent governmental body, the Central Committee on Research Involving Human Subjects (or Central Committee), which regulates the review of research proposals by accredited Medical Research Ethics Committees (MRECs). The legal basis was founded in 1999 with the Medical Research Involving Human Subjects Act. The review system is a decentralised arrangement since most research proposal are reviewed by the 30 accredited MRECs in the country. It is a controlled system in which the Central Committee is responsible for the accreditation and oversight of the MRECs and can make legally binding directives for these committees. The assessment of research proposals is an integrated peer review process in which all documents of the research file are reviewed by experts in one committee only. A small number of research proposals are assessed by the Central Committee and not by accredited MRECs. These proposals are on specific research categories such as gene therapy, cell therapy and embryo research. The review of research with surplus human embryos is regulated separately in the Embryos Act. The Central Committee provides support to the accredited MRECs and to researchers and sponsors. It is currently developing an internet portal to reduce the bureaucracy and make the review process more efficient and transparent. The Central Committee stimulates confidence on medical research in society by providing a public trial registry with core data on reviewed research proposals.     

Individuals high in neuroticism are not more reactive to adverse events

Numerous studies have related neuroticism to negative emotional outcomes of adverse life events, including post-traumatic stress disorder (PTSD) symptoms. However, the nature of the relationship between neuroticism and post-trauma symptoms is unclear. The purpose of this study was to prospectively examine whether individuals high in neuroticism, relative to low neuroticism individuals, show a larger increase in symptoms after an adverse event. A sample of infantry troops completed questionnaires before deployment to Iraq (n = 214) and about five months (n = 170; 76%) thereafter. The findings showed that, after controlling for an indicator of trauma severity, (a) higher neuroticism individuals reported more PTSD symptoms, depression symptoms, and somatic problems after negative events, and (b) these relationships disappeared after controlling for pre-trauma symptoms. There were no significant differences between individuals high and low in neuroticism in the increase in symptoms from pre to post-trauma. This suggests that individuals high in neuroticism are not more reactive to adverse events.