Presymptomatic Testing for Neurogenetic Diseases in Brazil: Assessing Who Seeks and Who Follows through with Testing

Diagnostic tests are available to detect several mutations related to adult-onset, autosomal dominant, neurodegenerative diseases. We aimed to describe our experience in a presymptomatic testing program run by the Brazilian Public Health System from 1999 to 2009. A total of 184 individuals were eligible for presymptomatic testing due to a risk for spinocerebellar ataxia (SCA) - SCA3 (80%), Huntington’s disease (11.9%), familial amyloidotic neuropathy (4.3%), SCA1, SCA2, SCA6, or SCA7. Most were women (70%), married (54%), and had children prior to presymptomatic testing (67%). Their mean age at entrance was 34 (SD = 11 years). Educational level was above the average Brazilian standard. After receipt of genetic counseling, 100 individuals (54%) decided to undergo testing; of these, 51 were carriers. Since no individual returned for post-test psychological evaluation, we conducted a subsequent survey, unrelated to test disclosures. We contacted 57 individuals of whom 31 agreed to participate (24 had been tested, 7 had not). Several ascertainment concerns relating to these numerous losses prevented us from generalizing our results from this second survey. We concluded that: decision-making regarding presymptomatic testing seems to be genuinely autonomous, since after genetic counseling half the individuals who asked for presymptomatic testing decided in favor and half decided against it; general characteristics of Brazilians who sought presymptomatic testing were similar to many European samples studied previously; and individuals at risk for SCA3 may be at greater risk of depression. Although no clear-cut reason emerged for rejection of follow-up psychological sessions after presymptomatic testing, this finding suggests adjustments to our presymptomatic testing program are necessary.     

The use of virtual reality in the study, assessment, and treatment of body image in eating disorders and nonclinical samples: a review of the literature

This article reviews research into the use of virtual reality in the study, assessment, and treatment of body image disturbances in eating disorders and nonclinical samples. During the last decade, virtual reality has emerged as a technology that is especially suitable not only for the assessment of body image disturbances but also for its treatment. Indeed, several virtual environment-based software systems have been developed for this purpose. Furthermore, virtual reality seems to be a good alternative to guided imagery and in vivo exposure, and is therefore very useful for studies that require exposure to life-like situations but which are difficult to conduct in the real world. Nevertheless, review highlights the lack of published controlled studies and the presence of methodological drawbacks that should be considered in future studies. This article also discusses the implications of the results obtained and proposes directions for future research.     

Psychometric properties of the questionnaire of sociocultural influences on the aesthetic body shape model (CIMEC-26) in female Spanish adolescents

The purpose of the present study was to analyse the psychometric properties of the 'Questionnaire of Sociocultural Influences on the Aesthetic Body Shape Model' (CIMEC-26) in a Spanish adolescent population. This questionnaire measures the influence of agents and situations that transmit the current aesthetic model, and assesses environmental influences favouring thinness. The CIMEC-26 was administered to a sample of 4031 female primary and secondary school students ranging in age from 10 to 17 years (M?=?14, SD?=?1.34). Results suggested that the CIMEC-26 has acceptable internal consistency (α?=?.93). The oldest group (15-17 years) had the highest scores on all factors and the highest total scores, suggesting greater influence of the aesthetic body shape model and higher vulnerability to social pressure to achieve it. Factor analysis suggested three moderately interrelated components of the scale. Confirmatory factor analysis showed that both the three-factor solution and the original five-factor structure had good fit indices, although the latter showed the best fit. The CIMEC-26 proved to be an effective instrument for research on the social influence on the aesthetic body model in female adolescents.     

Developmental pattern of digit span in Spanish population

This study examined in a Spanish population the developmental pattern of digit span, as an index of one of the components of Baddeley's working memory--the phonological loop. A verbal digit span was administered to 570 participants ranging from 5 to 17 years old. The results indicated that the digit memory span increases until age 17 as opposed to Anglo-Saxon data--where it is established that this span reaches a peak by age 15. Additionally, these results were compared to the performance in the same task of healthy elderly, Alzheimer disease patients, and Frontotemporal dementia patients, examined in a previous study. The analysis shows that the phonological loop is affected by age and not so much by dementias.     

Is an optimistic memory less easily influenced by negative than by positive emotions?

This work examines whether a positive personality trait, such as optimism, can reduce bias in differential words recalled after inducing a certain emotion. After showing a list of words with various emotional valences to a group of 59 subjects, a specific emotional state was induced. Subsequently, the subjects were asked to recall the list of words. The results obtained indicated that less optimistic subjects had a tendency to recall and recognize a greater number of negative words when in a negative emotional condition. Statistical significance was reached in the female group's negative word recognition when experiencing negative emotion.     

Comparison between immigrant and Spanish native-born pathological gambling patients

The study compared clinical, psychopathological, and personality profiles between immigrants and Spanish native-born pathological gambling patients. A total of 1,601 native-born and 133 immigrant patients attending treatment at a specialized hospital unit were administered a battery of questionnaires during clinical assessment. Outcome measures were compared between both groups and the incremental predictive accuracy of the area of origin was examined using a regression model. Native-born Spaniards showed a mean 2.6 yr. greater duration of the disorder, while immigrants scored higher on South Oaks Gambling Screen, frequency of going to casinos, and total money spent (in a single day and/or to recover losses). General psychopathology and personality scores did not differ between the cohorts. However, immigration from Asia had a statistically significantly incremental validity for pathological gambling in South Oaks Gambling Screen scores. Both cohorts shared more similarities than differences in their gambling profiles.     

Reliability and validity evidence of the Out-group Threat Perception Scale (OTPS)

This study aimed to analyze the psychometric properties of a new scale: the Out-group Threat Perception Scale (OTPS). The OTPS was designed to measure the perception of out-group threat, an important psychosocial variable that is closely related to negative attitudes towards out-groups. Three hundred and two Spanish participants responded to the OTPS in reference to the following out-groups: Moroccans (N= 102), Romanians (N= 101) and Ecuadorian immigrants (N= 99). The reliability and item analyses showed that the scale had good internal consistency. Factor analyses yielded two independent dimensions: Realistic Threat and Symbolic Threat. Correlational analyses showed that the OTPS correlated significantly with several psychosocial variables. The present findings suggest that the OTPS is a reliable and valid measure, and it can be a useful instrument to study intergroup relationships in our country.     

System of Spheres-based Multiple Contractions

We propose a new class of multiple contraction operations — the system of spheres-based multiple contractions — which are a generalization of Grove’s system of spheres-based (singleton) contractions to the case of contractions by (possibly non-singleton) sets of sentences. Furthermore, we show that this new class of functions is a subclass of the class of the partial meet multiple contractions.     

Prioritized and Non-prioritized Multiple Change on Belief Bases

In this article we explore multiple change operators, i.e., operators in which the epistemic input is a set of sentences instead of a single sentence. We propose two types of change: prioritized change, in which the input set is fully accepted, and symmetric change, where both the epistemic state and the epistemic input are equally treated. In both kinds of operators we propose a set of postulates and we present different constructions: kernel changes and partial meet changes.