Brain weights correlate with behavioral parameters in individual inbred mice housed in a common and enriched environment

Fifty 8-week-old Balb/c mice were individually identified and housed together in a large and enriched environment for 5 months. Maze and open field exploration, response to an aversive noise, swimming, and induced grooming tests were applied to each mouse in an initial search for possible relationships between brain morphology and spontaneous behavior in isogenic individuals living in a complex social and physical environment. The tasks generated 39 quantitative behavioral indices which include locomotion, rearing, still, and grooming bout frequencies, latencies, total, and mean bout durations. At the end of the tests, the 7-month-old mice were sacrificed and the fresh weights of their whole brain, cerebellum, brain stem, diencephalon, telencephalon, and prosencephalon were rapidly obtained. Behavioral data have wide variations and do not adjust to normal population distributions. Means of the same parameter differ between tests. A Spearman correlation matrix of all data yielded many significant correlations between indices of the same task which can be interpreted in terms of time budget and sequence probability. Significant correlations between indices of different tests suggest diverse emotionalities, exploratory strategies, and motor skills. The correlations between body and brain weights and among separate brain regions were not significant. There were several low but significant correlations between brain weights and behavioral indices. Such correlations, the resulting factors, and significant behavioral differences between mice with large and small brains suggest that mice displaying low motor activity in novel environments have larger brains and forebrain/hindbrain ratios than mice with high activity, and that animals with high scores of some specific behaviors have larger brain areas physiologically related to such behaviors.(ABSTRACT TRUNCATED AT 250 WORDS)     

Truthlikeness without truth: A methodological approach

In this paper, an attempt is made to solve various problems posed to current theories of verisimilitude: (1) the (Miller's) problem of linguistic variance; (2) the problem of which are the best scientific methods for getting the most verisimilar theories; and (3) the question of the ontological commitment in scientific theories. As a result of my solution ot these problems, and with the help of other considerations of epistemological character, I conclude that the notion of Tarskian truth is dispensable in a rational (and realist) interpretation of the scientific enterprise. As a logical result, however, falsificationism will be vindicated.

... and in brief, a speaker must always aim at verisimilitude, and send the truth packing.

Plato,Phaedrus, 272 EI want to express my gratitude to Professors García-Bermejo, Niiniluoto, and Zofío for interesting comments and critiques of several of the ideas in this paper, and to Miss Karen Firnich for correcting my English. I am also thankful to an anonymous referee who indicated several dark points on a previous version of my article.     

Visual perception of surface curvature: psychophysics of curvature detection induced by motion parallax

The continuous approach to optic-flow processing shows that the curvature of a moving surface is related to a second spatial derivative of the velocity field, the spin variation (Droulez & Cornilleau-Pérès, 1989). With this approach as a theoretical framework, visual sensitivity to the curvature of a cylinder in motion was measured using a task of discrimination between cylindrical and planar patches. The results confirm the predictions suggested by the theory: (1) Sensitivity to curvature was always greater when the cylinder axis and the frontal translation were parallel than when they were orthogonal. The ratio of curvature detection thresholds in the two cases was between 1.3 and 2.5; the value predicted from the spin variation theory is about 2. (2) Sensitivity to curvature increased strongly with the velocity of the motion but was only weakly affected by its amplitude and the duration of viewing for the range of values used in our experiments.