In semantic flanker tasks, target categorization response times are affected by the semantic compatibility of the flanker and target. With positive and negative category exemplars, we investigated the influence of evaluative congruency (whether flanker and target share evaluative valence) on the flanker effect, using behavioral and electrophysiological measures. We hypothesized a moderation of the flanker effect by evaluative congruency on the basis of the assumption that evaluatively congruent concepts mutually facilitate each other’s activation (see Schmitz & Wentura in Journal of Experimental Psychology: Learning, Memory, and Cognition 38:984–1000, 2012). Applying an onset delay of 50 ms for the flanker, we aimed to decrease the facilitative effect of an evaluatively congruent flanker on target encoding and, at the same time, increase the facilitative effect of an evaluatively congruent target on flanker encoding. As a consequence of increased flanker activation in the case of evaluative congruency, we expected a semantically incompatible flanker to interfere with the target categorization to a larger extent (as compared with an evaluatively incongruent pairing). Confirming our hypotheses, the flanker effect significantly depended on evaluative congruency, in both mean response times and N2 mean amplitudes. Thus, the present study provided behavioral and electrophysiological evidence for the mutual facilitation of evaluatively congruent concepts. Implications for the representation of evaluative connotations of semantic concepts are discussed. 相似文献
Among the extensive literature on the first Critique, very few commentators offer a thorough analysis of Kant's conception of inner sense. This is quite surprising since the notion is central to Kant's theoretical philosophy, and it is very difficult to provide a consistent interpretation of this notion. In this paper, I first summarize Kant's claims about inner sense in the Transcendental Aesthetic and show why existing interpretations have been unable to dissolve the tensions arising from the conjunction of these claims. Secondly, I present my own reconstruction of Kant's model of inner sense, relying essentially on Kantian considerations found in the B‐version of the Transcendental Deduction. My main idea is that inner sense, for Kant, is a passive faculty that gets affected by the understanding performing its figurative synthesis on material given in outer sense. In the remainder of the paper, I highlight a few consequences of my interpretation and outline ways to deal with some objections. 相似文献
Depersonalization (DP), or feelings of detachment from one’s self or one’s surroundings (i.e., derealization, DR), is considered a maladaptive stress response, frequently occurring in anxiety disorders, depression or as a primary disorder. However, the pathogenesis of DP/DR symptoms is little understood. The present study aimed to elucidate the influence of unresolved attachment status and the oxytocin receptor gene (OXTR) rs53576 polymorphism on DP/DR symptoms. The study sample consisted of 84 women, including 43 depressed patients and 41 control subjects, aged 19–52. DP/DR symptoms were measured with the Cambridge Depersonalization Scale; unresolved attachment status was assessed with the Adult Attachment Interview. OXTR rs53576 genotypes were obtained from blood samples. We found a highly significant gene–environment interaction: Individuals with unresolved attachment status were significantly more depersonalized when they carried the GG-allele than A-allele carriers than not unresolved subjects. There was no statistically significant main influence of OXTR genotypes or unresolved attachment status on DP/DR symptoms. We suggest that the GG-allele and unresolved attachment status might be considered as risk factors in the etiology of DP/DR symptoms. Replication is needed in larger samples including male subjects. 相似文献
Attention-deficit/hyperactivity disorder (ADHD) is a childhood-onset condition that may continue into adulthood. When assessing adult patients, clinicians usually rely on retrospective reports of childhood symptoms to evaluate the age-of-onset criterion. Since inaccurate symptom recall may impede the diagnosis and treatment of ADHD, knowledge about the factors influencing retrospective reports is needed. This longitudinal study investigated (a) the accuracy of retrospective symptom ratings by adult participants with a childhood diagnosis of ADHD (self-ratings) and parents or significant others (proxy ratings), and (b) the influence of current ADHD symptom severity and ADHD-associated impairments on retrospective symptom ratings. Participants (N =?55) were members of the Cologne Adaptive Multimodal Treatment (CAMT) study who had been referred and treated for ADHD in childhood and were reassessed in adulthood (average age 27 years). Participants’ retrospective self-ratings were substantially lower than, and did not correlate with, parents’ ADHD symptom ratings provided at study entry, while retrospective symptom ratings provided by proxy respondents correlated moderately with parents’ childhood ratings. In addition, participants were more likely to underreport childhood symptoms (79%) and more frequently denied the presence of three or more childhood symptoms (17%) compared to proxy respondents (65% underreporting, 10% false-negative recall). Proxy respondents’ symptom recall was best predicted by childhood ADHD, while participants’ symptom recall was best predicted by current ADHD symptom severity. ADHD-associated impairments were not correlated with symptom recall after controlling for childhood ADHD. Together, these findings suggest a recall bias in adult patients and question the validity of retrospective reports, even in clinical samples.
When presented with novel but semantically related elements after learning verbal material, healthy participants tend to endorse these items as previously learned. This reflects the normal integration and association of novel verbal information into long-term memory. How obstructive sleep apnoea (OSA) negatively impacts verbal memory performance, and whether deficits are reversible following positive airway pressure (PAP) treatment, remain elusive. We investigated immediate and delayed OSA- and PAP treatment-related effects on verbal memory integration, using a false memory paradigm. Twenty-three patients with OSA learned lists of words semantically related to target non-presented words (1) at baseline after a polysomnography diagnosis night, (2) after a consecutive polysomnography night under PAP titration, and (3) after three months of compliant PAP treatment. At each session, participants learned 10 different lists of words, each list comprising 15 semantically related items. They had then to recognize 15 minutes later (after an intermediate vigilance task) previously learned words within a list including studied words (learned), unstudied but semantically related items (lures), and non-related unstudied items (controls). Sleep quality and fatigue questionnaires, and psychomotor vigilance tests (PVT) were administered at each session. PAP treatment led to OSA remission and improvement in objective and subjective sleep quality. Crucially, recognition of learned and lure words increased after the first night under treatment and remained stable three months later, suggesting successful memory integration and restoration of semantic processes. No treatment-related outcome was found on PVT performance. OSA exerts a detrimental but PAP-reversible effect on verbal learning and semantic memory integration mechanisms underlying the acquisition of novel memory representations. 相似文献
The categorical approach of diagnosing mental disorders entails the problem of frequently occurring comorbidities, suggesting a more parsimonious structure of psychopathology. In this study, we therefore aim to assess how affective dysregulation (AD) is associated with attention-deficit/hyperactivity disorder (ADHD) and oppositional defiant disorder (ODD) in children. To assess AD in children aged 8–12 years (n?=?391), we employed the parent version of a newly constructed parent rating scale. Following item reduction, we conducted exploratory and confirmatory factor analyses to establish a factorial structure of AD. One core dimension was identified, comprising irritability and emotional impulsivity, and two smaller dimensions, comprising positive emotionality and exuberance. Subsequently, we examined five different latent factor models – a unidimensional model, a first-order correlated factor model, a second-order correlated factor model, a traditional bifactor model, and a bifactor S-1 model, in which the first-order factor AD-Irritability/Emotional Impulsivity (II) was modeled as the general reference factor. A bifactor S-1 model with the a priori defined general reference domain AD-II provided the best fit to our data and was straightforward to interpret. This model showed excellent model fit and no anomalous factor loadings. This still held true, when comparing it to bifactor S-1 models with ADHD/ODD-related reference factors. Differential correlations with emotion regulation skills and the established Parent Proxy Anger Scale validate the interpretation of the different dimensions. Our results suggest that irritability/emotional impulsivity might be a common core feature of ADHD and ODD.
Cognitive deficits are thought to be responsible for some of the symptoms and dysfunction in schizophrenia. Recent research on the anterior cingulate cortex supports this assumption. More detailed and definitive evidence for this association will require identification of specific neural networks whose abnormal structure, connections or activity create the cognitive deficits in question. 相似文献