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Zwissler B Koessler S Engler H Schedlowski M Kissler J 《Neurobiology of learning and memory》2011,95(3):346-354
It has been shown that stress affects episodic memory in general, but knowledge about stress effects on memory control processes such as directed forgetting is sparse. Whereas in previous studies item-method directed forgetting was found to be altered in post-traumatic stress disorder patients and abolished for highly arousing negative pictorial stimuli in students, no study so far has investigated the effects of experimentally induced psycho-social stress on this task or examined the role of positive picture stimuli. In the present study, 41 participants performed an item-method directed forgetting experiment while being exposed either to a psychosocial laboratory stressor, the Trier Social Stress Test (TSST), or a cognitively challenging but non-stressful control condition. Neutral and positive pictures were presented as stimuli. As predicted, salivary cortisol level as a biological marker of the human stress response increased only in the TSST group. Still, both groups showed directed forgetting. However, emotional content of the employed stimuli affected memory control: Directed forgetting was intact for neutral pictures whereas it was attenuated for positive ones. This attenuation was primarily due to selective rehearsal improving discrimination accuracy for neutral, but not positive, to-be-remembered items. Results suggest that acute experimentally induced stress does not alter item-method directed forgetting while emotional stimulus content does. 相似文献
184.
Stern J Candia V Porchet RI Krummenacher P Folkers G Schedlowski M Ettlin DA Schönbächler G 《Neurobiology of learning and memory》2011,95(3):326-334
Physiological studies of placebo-mediated suggestion have been recently performed beyond their traditional clinical context of pain and analgesia. Various neurotransmitter systems and immunological modulators have been used in successful placebo suggestions, including Dopamine, Cholecystokinin and, most extensively, opioids. We adhered to an established conceptual framework of placebo research and used the μ-opioid-antagonist Naloxone to test the applicability of this framework within a cognitive domain (e.g. memory) in healthy volunteers. Healthy men (n=62, age 29, SD=9) were required to perform a task-battery, including standardized and custom-designed memory tasks, to test short-term recall and delayed recognition. Tasks were performed twice, before and after intravenous injection of either NaCl (0.9%) or Naloxone (both 0.15 mg/kg), in a double-blind setting. While one group was given neutral information (S-), the other was told that it might receive a drug with suspected memory-boosting properties (S+). Objective and subjective indexes of memory performance and salivary cortisol (as a stress marker) were recorded during both runs and differences between groups were assessed. Short-term memory recall, but not delayed recognition, was objectively increased after placebo-mediated suggestion in the NaCl-group. Naloxone specifically blocked the suggestion effect without interfering with memory performance. These results were not affected when changes in salivary cortisol levels were considered. No reaction time changes, recorded to uncover unspecific attentional impairment, were seen. Placebo-mediated suggestion produced a training-independent, objective and Naloxone-sensitive increase in memory performance. These results indicate an opioid-mediated placebo effect within a circumscribed cognitive domain in healthy volunteers. 相似文献
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Claudia Kuhnle Manfred Hofer Britta Kilian 《The British journal of educational psychology》2012,82(4):533-548
Background. Recently, several studies have shown that strength of self-control is a crucial factor in determining positive outcomes in individuals’ lives. Most attention has been directed to the relationships that self-control has with learning and academic achievement. Aims. This article analyses the effects of self-control not only on school grades but also on the experience of life balance and flow. It is theorized that students with a higher level of self-control are better able to distribute their time in a satisfying way over academic and leisure matters, and are better able to shield their studying against distractions. Samples. A total of 697 eighth graders with a mean age of 13.4 years participated in the longitudinal study. Method. Students completed a questionnaire containing measures of self-control, school grades, subjective life balance, and flow while studying at the beginning and at the end of the school year. Structural equation modelling was used to analyse the relationships between the constructs. Results and conclusions. Results of cross-lagged analyses show that self-control predicted school grades, life balance, and flow. The findings suggest that self-control may assist adolescents to be better prepared, not only for school, but also for coordinating their investments in different areas of their lives. 相似文献
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Fichter MM Quadflieg N Nisslmüller K Lindner S Osen B Huber T Wünsch-Leiteritz W 《Behaviour research and therapy》2012,50(3):180-190
Technological advancements allow new approaches to psychotherapy via electronic media. The eating disorder literature currently contains no studies on internet intervention in anorexia nervosa (AN). This study presents a RCT on an internet-based relapse prevention program (RP) over nine months after inpatient treatment for AN. The sample comprised 258 women, randomized to the RP or treatment as usual (TAU). Expert- and self-ratings were evaluated by intent-to-treat analyses. Concerning age, age at onset and comorbidity, both groups were comparable at randomization. During the RP, the intervention group gained weight while the TAU group had minimal weight loss. RP completers gained significantly more body weight than patients in the TAU condition. Group-by-time comparisons for eating-related cognitions and behaviors and general psychopathology showed a significantly more favorable course in the RP program for "sexual anxieties" and "bulimic symptoms" (interview), and "maturity fears" and "social insecurity" (EDI-2). General psychopathology showed no significant group-by-time interaction. Important factors for successful relapse prevention were adherence to the intervention protocol and increased spontaneity. Considering the unfavorable course and chronicity of anorexia nervosa (AN), internet-based relapse prevention in AN following inpatient treatment appears a promising approach. Future internet-based programs may be further improved and enhanced. 相似文献
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The association between loneliness and suicidality has been documented in many studies, but these studies have been limited by cross-sectional designs and the use of adult-only populations. The purpose of the current study was to overcome these limitations by (a) investigating whether the link between loneliness and suicidal thoughts and behaviors occurs cross-sectionally, longitudinally, or both and (b) investigating how the link between loneliness and suicidality might be influenced by different demographic variables, including gender, ethnicity, and socioeconomic status. Logistic regression analyses were used to analyze data from a large sample (N = 937) of youth from the NICHD Study of Early Child Care. Results indicated that loneliness at age 15 years was concurrently associated with both suicidal ideation and suicidal behavior at age 15 years. Loneliness in middle childhood was longitudinally associated with suicidal behaviors at age 15 years, but not with suicidal ideation at age 15 years. None of the demographic characteristics influenced these associations. 相似文献
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“Beware of understanding!” Lacan’s structural analysis: theory and practice of interpretation. This paper investigates the relationship of understanding and countertransference analysis in the process of analytical interpretation. Here self-image of the analyst is crucial concerning the direction of the analysis. As field and function of speech are pivotal, they will be briefly sketched to clarify the structural-analytic starting point of the following arguments. The basis of the ideas is a definition of the unconscious as what is not conscious available. Should the analyst see himself as the “knowing” one, as his patient also assumes, a false assurance will result and the analysis will lead nowhere. This is typical of a “forced” transference analysis in the here and now. The alternative is a strategy of hints, whose premise is, that we do not know. This assumption makes it unnecessary to rely on countertransference analysis. Instead, the spoken word and its contradictions are in the focus. This analytical attitude makes listening to the “subject of the unconscious” possible by means of the analyst and his hints. 相似文献