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Objectives
We studied adults with autism spectrum disorder living in a specialized residential care home (n = 148). The participants’ behavioral problems were assessed using the French-language Scale for the Observation of Behavioral Problems in Adults with Autism (Échelle Pour l’Observation des Comportements-problèmes d’Adultes avec Autisme, EPOCAA; Recordon-Gaboriaud & Granier-Deferre). The study's main objectives were to (i) replicate the data from the EPOCAA reference group in a new sample of institutionalized adults, and (ii) study the impact of intellectual disability and medication on the EPOCAA scale. Our first hypothesis was that the severity of intellectual impairment would be associated with a greater likelihood of major behavioural problems. Our second hypothesis was that treatment (or the absence of treatment) with psychotropic and/or anti-epileptic medications would interact with the behavioural problems evaluated on the EPOCAA.Method
We first used Cohen's d to compare the results from our sample with those given in the EPOCAA. Next, we performed a multivariate analysis of covariance with intellectual impairment, sex, the use of anti-epileptic medications (as a yes/no binary variable), and the use of psychotropic medications (as a yes/no binary variable) as fixed factors, and age as a covariate.Results
All patients suffered from profound to severe intellectual impairment and low autonomy, which justified their permanent residence in a care home. A behavioral assessment of the study participants showed that the overall EPOCAA scores were much lower in the study sample than in the scale's reference sample. The combination of profound intellectual disability and autism was associated with more behavioral problems than severe intellectual impairment. The residents’ intellectual impairments were predominantly related to two domains (object use and sensorimotor activities/stereotypy) and to the severity of difficulties in the social interactions domain. The second hypothesis was not confirmed: the presence or absence of the various medications did not appear to influence behavioral problems. These results are discussed with a view to improving the residents’ quality of life. 相似文献Design: Eighty-one participants completed a battery of self-report scales within 10 days before the start of radiotherapy (T1) and within 10 days after its end (T2; approximately 6 weeks after T1). HF-HRV at rest was measured at T1.
Results: Canonical correlation analyses revealed that higher levels of experiential avoidance and expressive suppression were cross-sectionally associated with higher levels of all symptoms, except pain, at T1 and at T2 (both p’s?<?0.0001). Higher levels of suppression and reappraisal at T1 were marginally associated with reduced FCR and with increased depression and fatigue between T1 and T2 (p?=?0.07). HF-HRV was not associated with symptoms cross-sectionally or prospectively.
Conclusions: Although preliminary, these results are consistent with the hypothesis that maladaptive ER strategies, assessed subjectively, may cross-sectionally act as a transdiagnostic mechanism underlying several cancer-related psychological symptoms. 相似文献