论基因检测之应用及其ELSI议题的文化意涵

在基因科技的革命性发展过程中,整体社会似乎未能提供一个充分保障研究参与者与科学研究之完整性的机制.以台湾面临基因检测之挑战的经验为例,探讨了伦理、法律与社会意涵(Ethial,Legal and Social Implications,ELSI)研究如何完善规范体制的实务应用需求,并兼顾人权团体所期待的妥善保护研究参与者.     

A two‐part mixed effects model for cigarette purchase task data

The Cigarette Purchase Task is a behavioral economic assessment tool designed to measure the relative reinforcing efficacy of cigarette smoking across different prices. An exponential demand equation has become a standard model for analyzing purchase task data, but its utility is compromised by its inability to accommodate values of zero consumption. We propose a two‐part mixed effects model that keeps the same exponential demand equation for modeling nonzero consumption values, while providing a logistic regression for the binary outcome of zero versus nonzero consumption. Therefore, the proposed model can accommodate zero consumption values and retain the features of the exponential demand equation at the same time. As a byproduct, the logistic regression component of the proposed model provides a new demand index, the “derived breakpoint”, for the price above which a subject is more likely to be abstinent than to be smoking. We apply the proposed model to data collected at baseline from college students (N = 1,217) enrolled in a randomized clinical trial utilizing financial incentives to motivate tobacco cessation. Monte Carlo simulations showed that the proposed model provides better fits than an existing model. We note that the proposed methodology is applicable to other purchase task data, for example, drugs of abuse.     

Analgesic effect of Facebook: Priming with online social networking may boost felt relatedness that buffers against physical pain

Social networking sites (SNSs) are extremely popular for providing users with a convenient platform for acquiring social connections and thereby feeling relatedness. Plenty of literature has shown that mental representations of social support can reduce the perception of physical pain. The current study tested whether thinking about SNS would interfere with users’ perceptions of experimentally induced pain. Ninety‐six undergraduate Facebook users were recruited to participate in a priming‐based experiment. They were randomly assigned to one of the three study conditions (SNS prime, neutral prime, or no prime) via rating the aesthetics of logos. The results showed that participants exposed to SNS primes reported less pain of immersion in hot water than did both control groups (neutral‐ and no‐prime). Felt relatedness mediated the link between SNS primes and diminished pain perceptions. This research provides the first demonstration that thinking about SNS can lower experienced physical pain among Facebook users. Online social networking may serve as an analgesic buffer against pain experience than previously thought. The SNS‐enabled analgesia has far reaching implications for pain relief applications and the enhancement of well‐being in human‐interaction techniques.     

Made in America: Perspectives on Friendship in West African Immigrant Families

This qualitative study compared West African immigrant parents’ and adolescents’ perspectives on parental monitoring of adolescents’ peer groups. Parents (n = 31) and adolescent children (n = 25) were interviewed using focus groups and individual interviews, and data were analyzed using a grounded theory approach. Parents expressed a general concern about external influences on their children, particularly their mistrust of their children’s friends. Adolescents reported that they were aware of their parents’ fears and described their attempts to manage their parents’ concerns while simultaneously maintaining friendships with same-ethnic and other-ethnic peers. This study offers both parent and adolescent perspectives in an effort to better understand adolescents’ peer socialization and parental monitoring among West African immigrant families, one of the fastest growing demographic groups in the United States. Recommendations for mental health professions are discussed.     

Intergenerational Transmission of Trauma-Related Distress: Maternal Betrayal Trauma,Parenting Attitudes,and Behaviors

The purpose of this study was to elucidate mechanisms involved in the intergenerational transmission of trauma-related distress. This study investigated whether betrayal trauma (BT; abuse by a person close to the victim) and specific parenting attitudes and behaviors among mothers with child abuse histories predicted internalizing and externalizing symptoms in their children. Mothers and children (ages 7–11) were recruited for a project on parenting and stress (N = 72). Maternal betrayal trauma predicted both internalizing (β = 0.33, p < .01) and externalizing symptoms (β = 0.25, p < .05) even when controlling for mothers’ trauma-related symptoms. Negative attitudes toward limit setting predicted externalizing symptoms (β = ?0.33, p < .05). Poorer communication (β = ?0.39, p < .05) but higher parenting satisfaction (β = 0.38, p < .01) predicted internalizing symptoms. These findings demonstrate the importance of assessing maternal trauma and parenting characteristics as part of interventions with symptomatic children.     

Cognitive adaptation and its consequences: a test of cognitive continuum theory

Cognitive Continuum Theory (CCT) is an adaptive theory of human judgement and posits a continuum of cognitive modes anchored by intuition and analysis. The theory specifies surface and depth task characteristics that are likely to induce cognitive modes at different points along the cognitive continuum. The current study manipulated both the surface (information representation) and depth (task structure) characteristics of a multiple‐cue integration threat assessment task. The surface manipulation influenced cognitive mode in the predicted direction with an iconic information display inducing a more intuitive mode than a numeric information display. The depth manipulation influenced cognitive mode in a pattern not predicted by CCT. Results indicate this difference was due to a combination of task complexity and participant satisfacing. As predicted, analysis produced a more leptokurtic error distribution than intuition. Task achievement was a function of the extent to which participants demonstrated an analytic cognitive mode index, and not a function of correspondence, as predicted. This difference was likely due to the quantitative nature of the task manipulations. Copyright © 2000 John Wiley & Sons, Ltd.     

When Is Seeking Safety Functional? Taking a Pragmatic Approach to Distinguishing Coping From Safety

Currently, most exposure-based treatments call for clinicians to assess for and remove all safety behaviors during exposure tasks. However, the notion that safety behaviors are detrimental across all scenarios has recently been challenged, and research regarding the effects of safety behaviors on exposure outcomes is limited and inconsistent. In clinical practice, classifying a strategy as a safety behavior can be a complex and challenging endeavor, particularly when distinguishing between harmful safety behaviors and helpful coping behaviors. We outline an approach that emphasizes the pragmatic truth criterion and uses functional outcomes to classify behaviors as serving either safety or coping functions. Our focus on doing what “works” simplifies decision-making for clinicians and maintains the focus of treatment on enhancing functioning. We propose a model for using functional outcomes to distinguish between safety and coping behaviors and illustrate our approach through case examples.     

Physical stature influences character perception in women

It is well established that height influences the perceived character of men but very little evidence exists that the same influences of height exist for women. To investigate the effects of female height on perception of their character, we used a novel technique of digitally altering the perceived height of two women depicted in photographs such that the same targets appeared to be of tall or short stature to different participants. We asked participants to rate each of the two women on personal qualities and characteristics that reflected the instrumental/expressive distinction in masculine/feminine stereotypes. Overall, tall women were rated as more intelligent, affluent, assertive and ambitious than shorter women. A perceiver-sex difference was found such that men rated short females more highly than tall females on expressive characteristics while women raters did not. Thus, we provide the first direct evidence that female height influences perception of their character.     

唐前司命信仰的演变——兼谈人为宗教对民间神祇的吸收与改造

人为宗教在发展与传播过程中,有一个规律性的现象,就是对民间信仰中的神祇加以吸收与改造。其目的是为了更快地被人们接受和认同。司命是民间信仰的重要神祇,魏晋南北朝以前,其职责主要是掌管人的生死祸福,隋唐以后,司命渐与灶神合流。司命地位的变化就是这种规律性的体现。     

11~14岁超常儿童与普通儿童问题解决能力的发展比较

以北京市某中学和某小学11~14岁之间294名学生为被试, 其中超常儿童131人, 普通儿童163人。采用推箱子任务, 结合横向比较和纵向追踪数据, 从认知能力、元认知能力和认知效率三个维度来考察超常儿童与普通儿童问题解决能力的发展差异。结果发现超常儿童在问题解决能力的三个维度上均优于普通儿童, 两类儿童问题解决能力的发展模式不一致：超常儿童的问题解决能力发展先快后慢, 快速发展期在11~12岁半之间; 普通儿童的问题解决能力发展先慢后快, 快速发展期在12岁半~14岁之间。超常儿童与普通儿童的问题解决能力差异随年龄增大逐渐减小。