情绪复杂性对精神症状的影响途径及干预技术

情绪复杂性指的是个体情绪体验的多样性和分化度。情绪复杂性影响了精神症状的形成, 它不仅通过改变情绪调节策略的频率和程度来影响精神症状, 而且会影响情绪调节策略和精神症状之间的关系。基于情绪复杂性的干预增加了暴露治疗的疗效。正念能提升情绪复杂性, 但两者的作用机制可能有所差别。情绪复杂性的多角度测量、作用条件及脑机制应成为今后在临床领域的研究方向。     

Fragile X mental retardation protein levels increase following complex environment exposure in rat brain regions undergoing active synaptogenesis

Fragile X mental retardation protein (FMRP), which is absent in fragile X syndrome, is synthesized in vitro in response to neurotransmitter activation. Humans and mice lacking FMRP exhibit abnormal dendritic spine development, suggesting that this protein plays an important role in synaptic plasticity. Previously, our laboratory demonstrated increased FMRP immunoreactivity in visual cortex of rats exposed to complex environments (EC) and in motor cortex of rats trained on motor-skill tasks compared with animals reared individually in standard laboratory housing (IC). Here, we use immunohistochemistry to extend those findings by investigating FMRP levels in visual cortex and hippocampal dentate gyrus of animals exposed to EC or IC. Rats exposed to EC for 20 days exhibited increased FMRP immunoreactivity in visual cortex compared with animals housed in standard laboratory caging. In the dentate gyrus, animals exposed to EC for 20 days had higher FMRP levels than animals exposed to EC for 5 or 10 days. In light of possible antibody crossreactivity with closely related proteins FXR1P and FXR2P, FMRP immunoreactivity in the posterior-dorsal one-third of cerebral cortex was also examined by Western blotting following 20 days of EC exposure. FMRP levels were greater in EC animals, whereas levels of FXR1P and FXR2P were unaffected by experience. These results provide further evidence for behaviorally induced alteration of FMRP expression in contrast to its homologues, extend previous findings suggesting regulation of its expression by synaptic activity, and support the theories associating FMRP expression with alteration of synaptic structure both in development and later in the life-cycle.     

The Golden Rule and the potentiality principle: future persons and contingent interests

Duties to future persons are central to numerous key ethical issues including contraception, abortion, genetic selection, treatment of the environment, and population control. Nevertheless, we still seem to be lacking Parfit's 'Theory X', a general theory of beneficence whose appropriateness extends to future generations. Starting from the Golden Rule (TGR), R.M. Hare purportedly derived counterintuitive duties to potential people and 'the potentiality principle'. However, I argue that Hare's derivation involves a hidden and unjustifiable extension from TGR, and show how the most plausible form of TGR is compatible with multiple contradictory principles for the treatment of future persons. I appeal to our own preferences to argue that one extension of TGR follows the spirit of TGR, while the other is deeply implausible. Using the plausible extension, I derive a Contingent Interests Principle (CIP) that offers much promise as Parfit's elusive Theory X. In contrast to Hare's interpretation of TGR, this application provides solid justification for rejecting the potentiality principle.     

Factorial structure of the kidcope in Hong Kong adolescents

The Kidcope (A. Spirito, L. J. Stark, & C. Williams, 1988), a brief screening measure of coping strategies for children and adolescents, was subjected to exploratory and confirmatory factor analyses in a sample of adolescents in Hong Kong. A 2-factor model was found to fit the data when only the 2 emotional regulation items were treated separately and were allowed to load on the 2 different factors. Further analyses showed that factor loadings, factor variances, and factor covariance were invariant across age and gender. On the basis of the factor analyses, the authors created 2 composite scores, representing control-oriented and escape-oriented coping strategies. Implications for the use of the Kidcope in research and preventive intervention are discussed.     

Modulation of word-reading processes in task switching

The authors examined modulation of the simple act of word naming induced by the conflict arising when that task competes with color naming in a task-switching paradigm. Subjects alternated between naming a word printed in black and naming the color of a stimulus in 2 conditions. In the incongruent condition, the colored stimulus was an irrelevant word generating conflict, and in the neutral condition, color was carried by a row of asterisks. Subjects took substantially longer to name a word printed in black in the incongruent condition, implying a form of suppression. This modulation of the word-naming response was adaptive in that it led to more efficient color naming. The modulation effect was replicated using phoneme detection instead of word naming but not with lexical decision or visual comparison, implicating a phonological encoding process.     

Psychosocial predictors of delay of first sexual intercourse by adolescents.

This investigation predicted adolescents' delay of intercourse onset from attitudes, social norms, and self-efficacy about refraining from sexual intercourse. Age, gender, ethnicity, and parental education were also examined as predictors and moderators of the relationships among the 3 psychosocial determinants and onset. The participants (N = 827), part of a cohort initially surveyed in the 9th grade, reported at baseline that they had never engaged in intercourse. The multivariable proportional hazards regression model suggested that adolescents with more positive attitudinal and normative beliefs, as well as those with a parent who graduated from college, were less likely to engage in intercourse in the follow-up period (up to approximately 2 years). Interventions that include an objective to delay onset may benefit from addressing psychosocial determinants, especially attitudes and norms about sexual intercourse.     

Hong Kong Versus U.S. Negotiations: Effects of Culture,Alternatives, Outcome Scales,and Mediation1

This study investigates the effects of culture, BATNA (best alternative to a negotiated agreement), outcome scales, and mediation on negotiation outcomes. Six hundred three subjects from 2 countries (288 from Hong Kong and 315 from the United States) participated in 2-party negotiations that were either mediated or observed by a third party. In these negotiations, the Hong Kong negotiators obtained higher joint outcomes than did their U.S. counterparts. Also, in both Hong Kong and the United States, negotiators with a high BATNA obtained larger individual outcomes than did those with a low BATNA. Finally, mediation resulted in higher joint outcomes than did no mediation and had a stronger effect in US. (vs. Hong Kong) negotiations.