Impact of Firearm Availability and Gun Regulation on State Suicide Rates

Past studies on suicide have investigated the association of firearm ownership and suicide risk in the United States. The aim of the present study was to build on previous work by examining the impact of firearm storage practices and the strictness of firearm regulation on suicide rates at the state level. Data were compiled from primarily three sources. Suicide and firearm ownership information was obtained from the Centers for Disease Control and Prevention. Strictness of handgun regulation was derived from figures available at the Law Center to Prevent Violence, and controls were taken from the US Bureau of the Census. Mixed models were fitted to the data. Household firearm ownership was strongly associated with both suicide by all mechanisms, and firearm suicide. Storage practices had especially elevated consequences on suicide rates. Percent with loaded guns and gun readiness increased suicide rates, and strictness of gun regulation reduced suicide rates. Ready access to firearms can make a difference between life and death. Loaded and unlocked firearms within reach become risk factors for fatal outcomes from suicidal behavior. Future research might want to examine ways of obtaining more recent data on individual firearm ownership. This study proposes several policy recommendations for suicide prevention.     

Contrasting hippocampal and perirhinalcortex function using immediate early gene imaging

The perirhinal cortex and hippocampus have close anatomical links, and it might, therefore, be predicted that they have close, interlinked roles in memory. Lesion studies have, however, often failed to support this prediction, providing dissociations and double dissociations between the two regions on tests of object recognition and spatial memory. In a series of rat studies we have compared these two regions using the expression of the immediate early gene c-fosas a marker of neuronal activity. This gene imaging approach makes it possible to assess the relative involve-ment of different brain regions and avoids many of the limitations of the lesion approach. A very consistent pattern of results was found as the various hippocampal subfields but not the peri-rhinal cortex show increased c-fosactivity following tests of spatial learning. In contrast, the perirhinal cortex but none of the hippocampal subfields show increased c-fosactivity when presented with novel rather than familiar visual objects. When novel scenes are created by the spatial rearrangement of familiar objects it is the hippocampus and not the perirhinal cortex that shows c-foschanges. This double dissociation for gene expression accords with that found from lesion studies and highlights the different contributions of the perirhinal cortex and hippocampus to memory.     

SOCIAL STIMULUS PERCEPTION AND SELF-EVALUATION: EFFECTS OF MENSTRUAL CYCLE PHASE

Women in different phases of the menstrual cycle were compared to each other and to men in their responses to a social interaction stimulus: a videotape depicting a female nurse interacting with a hospitalized patient. Sex differences and cycle-phase differences were found for both affective and cognitive dimensions. Premenstrual women reported feeling more dominant, energetic, indifferent, negative, and somewhat more tense than women menstruating or women in the intermenstrual cycle phase. However, they did not differ from men in their affective ratings. Premenstrual women evaluated the nurse as less attractive than did men and they attributed greater responsibility for the nurse's behavior to the patient than men and intermenstrual women. Women in all groups evaluated the nurse as nicer and more pleasant, interesting, concerned and self-assured than did men. All women also felt more friendly toward the nurse and reported that they would be more comfortable asking her questions than the men did. The implications of these findings are discussed.     

Preconditions of predication: From qualia to quantum mechanics

Although in every inductive inference, an act of invention is requisite, the act soon slips out of notice. Although we bind together facts by superinducing upon them a new Conception, this Conception, once introduced and applied, is looked upon as inseparably connected with the facts, and necessarily implied in them. Having once had the phenomena bound together in their minds in virtue of the Conception men can no longer easily restore them back to the detached and incoherent condition in which they were before they were thus combined. The pearls once strung, they seem to form a chain by their nature. Induction has given them unity which it is so far from costing us an effort to preserve, that it requires an effort to imagine it dissolved — William Whewell, 1858. (Quoted from Butts (ed.), 1989, p. 143)