Episodic-like memory in zebrafish

Episodic-like memory tests often aid in determining an animal’s ability to recall the what, where, and which (context) of an event. To date, this type of memory has been demonstrated in humans, wild chacma baboons, corvids (Scrub jays), humming birds, mice, rats, Yucatan minipigs, and cuttlefish. The potential for this type of memory in zebrafish remains unexplored even though they are quickly becoming an essential model organism for the study of a variety of human cognitive and mental disorders. Here we explore the episodic-like capabilities of zebrafish (Danio rerio) in a previously established mammalian memory paradigm. We demonstrate that when zebrafish were presented with a familiar object in a familiar context but a novel location within that context, they spend more time in the novel quadrant. Thus, zebrafish display episodic-like memory as they remember what object they saw, where they saw it (quadrant location), and on which occasion (yellow or blue walls) it was presented.     

Linking metaphor comprehension with analogical reasoning: Evidence from typical development and autism spectrum disorder

We examined the relationship between metaphor comprehension and verbal analogical reasoning in young adults who were either typically developing (TD) or diagnosed with Autism Spectrum Disorder (ASD). The ASD sample was highly educated and high in verbal ability, and closely matched to a subset of TD participants on age, gender, educational background, and verbal ability. Additional TD participants with a broader range of abilities were also tested. Each participant solved sets of verbal analogies and metaphors in verification formats, allowing measurement of both accuracy and reaction times. Measures of individual differences in vocabulary, verbal working memory, and autistic traits were also obtained. Accuracy for both the verbal analogy and the metaphor task was very similar across the ASD and matched TD groups. However, reaction times on both tasks were longer for the ASD group. Additionally, stronger correlations between verbal analogical reasoning and working memory capacity in the ASD group indicated that processing verbal analogies was more effortful for them. In the case of both groups, accuracy on the metaphor and analogy tasks was correlated. A mediation analysis revealed that after controlling for working memory capacity, the inter-task correlation could be accounted for by the mediating variable of vocabulary knowledge, suggesting that the primary common mechanisms linking the two tasks involve language skills.     

Predicting others' actions via grasp and gaze: evidence for distinct brain networks

During social interactions, how do we predict what other people are going to do next? One view is that we use our own motor experience to simulate and predict other people's actions. For example, when we see Sally look at a coffee cup or grasp a hammer, our own motor system provides a signal that anticipates her next action. Previous research has typically examined such gaze and grasp-based simulation processes separately, and it is not known whether similar cognitive and brain systems underpin the perception of object-directed gaze and grasp. Here we use functional magnetic resonance imaging to examine to what extent gaze- and grasp-perception rely on common or distinct brain networks. Using a 'peeping window' protocol, we controlled what an observed actor could see and grasp. The actor could peep through one window to see if an object was present and reach through a different window to grasp the object. However, the actor could not peep and grasp at the same time. We compared gaze and grasp conditions where an object was present with matched conditions where the object was absent. When participants observed another person gaze at an object, left anterior inferior parietal lobule (aIPL) and parietal operculum showed a greater response than when the object was absent. In contrast, when participants observed the actor grasp an object, premotor, posterior parietal, fusiform and middle occipital brain regions showed a greater response than when the object was absent. These results point towards a division in the neural substrates for different types of motor simulation. We suggest that left aIPL and parietal operculum are involved in a predictive process that signals a future hand interaction with an object based on another person's eye gaze, whereas a broader set of brain areas, including parts of the action observation network, are engaged during observation of an ongoing object-directed hand action.     

Exploring the Effectiveness of a Mixed-Diagnosis Group Cognitive Behavioral Therapy Intervention Across Diverse Populations

Depression and anxiety are the most common mental health disorders seen in clinical practice and they are highly comorbid. Cognitive behavioral therapy (CBT) has been demonstrated as an effective treatment for both depression and anxiety but is often not available to all individuals who could benefit from it. This paper investigates the effectiveness of a mixed-diagnosis group CBT intervention that incorporates mindfulness meditation for individuals presenting with depression and/or anxiety: CBT Basics II. This intervention was evaluated across two distinct mental health programs to determine both if it can demonstrate positive results and if it is feasible to implement in these types of programs. Sample 1 (n = 42 completers) consisted of higher-functioning individuals in a general mental health program. Sample 2 (n = 53 completers) consisted of individuals with more chronic and severe mental health diagnoses. Overall, intent-to-treat analyses revealed improvements in psychiatric symptoms, and increases in CBT knowledge and mindfulness skill across both programs. This indicates that CBT Basics II is effective across diverse mental health populations and shows promise for improving access to CBT.     

Intergroup dynamics of extra-legal police aggression: An integrated theory of race and place

The police are empowered to use various forms of coercion to accomplish legitimate duties, but they also may employ them gratuitously in violation of law or departmental policy. These extra-legal behaviors range in severity from verbal abuse, such as racial slurs and profanity, to unjustified physical force resulting in severe injury or death. Racial and ethnic minorities, especially those residing in disadvantaged urban neighborhoods, may be disproportionately targeted for such practices. Scholars have offered several explanations for the differential employment of extra-legal police aggression, but an integrated theory of minority disadvantage has yet to be developed. In this article, we synthesize the existing literature into a model of extra-legal police aggression that considers intergroup dynamics of race and place. We argue that ordinary social-psychological processes triggered by the characteristics of neighborhoods explain extra-legal police aggression against minority citizens.     

Pyrrhonism in the Political Philosophy of Thomas Hobbes

The importance of Pyrrhonism to Hobbes's political philosophy is much greater than has been recognized. He seems to have used Pyrrhonist arguments to support a doctrine of moral relativity, but he was not a sceptic in the Pyrrhonist sense. These arguments helped him to develop his teaching that there is no absolute good or evil; to minimise the purchase of natural law in the state of nature and its restrictions on the right of nature; virtually to collapse natural law into civil law; and to make the sovereign the political, moral and theological epicenter of his political system.     

Approaching Homelessness: An Integral Re-Frame

This article explores a metaview of the many faces of homelessness. It analyzes an evolutionary meaning of home and suggests that ever-complexifying life conditions influence how societies enforce conformity to the status quo of homefulness. It goes on to describe how homelessness might be reframed as a complex adaptive form of survival for diversity generators who cannot or will not conform to the status quo. The article proposes an integral framework on which intervention strategies could be structured to provide evolutionary, appropriate, and flexible approaches to homelessness.