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排序方式: 共有119条查询结果,搜索用时 15 毫秒
1.
Differential effects of electroconvulsive shock on concurrent spatial memories: "old" memories are impaired while "new" memories are spared 总被引:1,自引:0,他引:1
W S Maki 《Behavioral and neural biology》1985,43(2):162-177
The effects of electroconvulsive shock (ECS) on spatial memory first reported by Shavalia, Dodge, and Beatty (1981, Behavioral and Neural Biology, 31, 261-273) were systematically replicated in two experiments. Rats acquired concurrent spatial memories in two 8-arm radial mazes. Each rat was allowed four choices in Maze 1 and then, after 2 h, four choices in Maze 2. After 2 h each rat was tested for retention in Maze 1 and, after 2 more h, was tested for retention in Maze 2. A single ECS was administered immediately after the fourth choice in Maze 2. Retention (as measured by accuracy of Choices 5-8) was diminished for Maze 1 but not for Maze 2. In the second experiment, the delay between the retention tests was eliminated (thus holding the ECS-Choice 5 interval constant for the two mazes). Once again retention of Maze 1 was impaired and retention of Maze 2 was spared; that finding suggests that ECS does not proactively affect radial-arm maze performance. The results of a third experiment converge on the same conclusion; ECS failed to reduce levels of spontaneous alternation. Therefore, ECS appears to interfere retroactively with relatively old spatial memories and newly established memories appear to be immune to the amnestic effects of ECS. Implications and various explanations are considered. 相似文献
2.
Previous work suggests that there may be fundamental differences between compensatory stepping responses evoked by postural perturbation and visually cued "volitional" stepping (e.g., gait initiation). In contrast to visual cueing, postural destabilization evokes an array of sensory inputs that are intrinsically linked to the mobilization of rapid compensatory responses. The hypothesis examined in this study was that this fundamental difference would lead to distinct changes in the temporal characteristics of the stepping response. Six healthy young adults were instructed to step quickly in response to either visual cueing or anterioposterior platform motion. Both forward and backward stepping responses were characterized, using measures of vertical ground reaction force. A stereotypical temporal patterning of the stepping response occurred in both stimulus conditions and both directions of stepping, and anticipatory postural adjustments were evident in all trials. However, postural destabilization led to a more rapid initiation and execution of the temporal pattern, in comparison with visually cued responses. The most pronounced effect was seen in the duration of the response, which was reduced by a factor of two, with approximately proportional foreshortening of both the preparatory and swing phases. The results suggest that sensory information conveying a state of instability has a distinct influence on the characteristics of a subsequent stepping reaction. The persistence of the anticipatory postural adjustments suggests that the failure to see this element of the response in previous studies may reflect fundamental differences between volitional and unplanned compensatory stepping. 相似文献
3.
Schretlen D Jayaram G Maki P Park K Abebe S DiCarlo M 《Journal of abnormal psychology》2000,109(1):134-138
Although cognitive deficits often accompany severe mental illness, their implications for everyday functioning remain poorly understood. In this study, an occupational therapist (OT) rated the everyday functioning of 105 adult psychiatric patients. Using demographic, clinical, and cognitive variables, the authors tested alternative models to account for the observed variability in OT ratings. Although age, education, and the presence of schizophrenia each contributed to a model that accounted for 27% of the variation in functional independence, adding terms for auditory divided attention and verbal learning increased the proportion of explained variance to 45% and decreased the beta weights for age and education--but not schizophrenia--to nonsignificant levels. These findings demonstrate the relevance of cognitive performance to everyday functioning in severe mental illness. They are discussed with respect to hypothesized determinants of psychiatric disability. 相似文献
4.
Spontaneous blinks as a criterion of visual fatigue during prolonged work on visual display terminals 总被引:3,自引:0,他引:3
Visual fatigue caused by prolonged work viewing a Visual Display Terminals (VDT) and of work reading a hard-copy were assessed by electromyogram (EMG) waveform and electrooculogram (EOG) waveform in spontaneous blinks as objective criteria, and by questionnaire of subjective feeling, and by task performance. The duration and the amplitude of the EMG of the orbicularis ocular muscle on the right side and the EOG of the vertical direction to the eyelid were measured for 10 subjects who participated in a figure task consisting of the addition of single-digit numbers on a VDT work or a work with a hard-copy. The mean values of the duration and the amplitude of the EMG and the EOG were evaluated by the averaging of 10 waveforms of the spontaneous blinks for all subjects. The time lag from the EMG to the EOG in the process of the generation of spontaneous blinks was also analyzed. These five parameters were evaluated during the work time. The mean values for the duration of the EMG increased gradually during the work time, but the amplitude did not show significant difference between the prework and a work time. There was no significant change of the duration of the EOG, but the mean amplitude of the EOG decreased as the work time progressed, and the time lag significantly extended. The blinks frequency increased relatively when using a VDT. The rate of fluctuation for these parameters was higher during use of a VDT than use of a hard-copy. The time lag at five hours of VDT work was extended by 90% based on the value at the pre-work. The symptoms of general fatigue and fatigue of the eyes increased linearly during the VDT work for six hours. The results indicated a significant correlation between the objective parameters for the activity of the spontaneous blinks, i.e., duration and amplitude of EMG and EOG, and the time lag between EMG and EOG, and the subjective feeling was recognized in the time course of the task. These experimental results suggested that the parameters regarding the EMG and the EOG for the spontaneous blinks were effective indices for assessing visual fatigue during prolonged VDT work. 相似文献
5.
Shinji Sakamoto Atsuko Tomoda Noboru Iwata Waka Aihara Toshinori Kitamura 《Journal of psychopathology and behavioral assessment》1999,21(1):37-49
The present study investigates whether highly self-preoccupied people (exhibiting a tendency to focus primarily on the self and to maintain self-focused attention) were more likely to experience major depressive episodes (MDEs) than those without such tendencies. One hundred nineteen young community residents, aged 18 to 21, took part in semistructured interviews, during which we investigated their past and present history of mental illness, including MDEs, as delineated by the Diagnostic and Statistical Manual of Mental Disorders (3rd ed. rev.; DSM-III-R). Self-preoccupation was measured by the Self-Preoccupation Scale (SPS). Of the 119 participants interviewed, the lowest and highest quarters in the SPS scores formed the low- and high-self-preoccupation (SP) groups. The lifetime prevalence of the DSM-III-R MDE was significantly greater among those high in SP than in the low SP group. Moreover, the high-SP group had significantly more depressive symptoms than the low-SP group. The contributory role of self-preoccupation to suicide ideation and the interpersonal aspects of self-preoccupation were discussed. 相似文献
6.
While many scholars have demonstrated the effectiveness of theatre-based knowledge mobilization, fewer studies have examined its psychological dimensions. This article examines some psychological theories that may account for the success behind theatre-based knowledge mobilization. Drawing from the Canadian Experience Project, a study about the labor market challenges of skilled immigrant workers, we show how theatre-based research dissemination efforts attempt to achieve optimal stress by using aesthetic distance processes. We maintain that this psychological capacity to attune to audience members, especially evident in forum theatre, makes theatre a particularly effective means for knowledge mobilization. 相似文献
7.
Tsubasa Mitsutake Maiko Sakamoto Kozo Ueta Etsuo Horikawa 《Journal of motor behavior》2018,50(4):467-472
The authors sought to investigate if short-term gaze stability exercises have an effect on postural stability of dynamic standing during neck movement in patients with posterior circulation stroke (PCS). Patients in both PCS and non-PCS groups were assigned to either an intervention or control group. The intervention group performed the gaze stability exercises for 10 min while the control group was merely resting. The center of pressure velocity was calculated to evaluate the postural stability. After intervention, PCS and non-PCS showed a significant reduction in center of pressure velocity during dynamic standing with eyes closed condition, and the PCS group showed a significant improvement in eye-opened condition. This study indicated that gaze stability exercises improve PCS patients' postural control, especially during dynamic standing. 相似文献
8.
Stigma prevents people with depression from seeking professional help, and effective strategies to reduce implicit stigmatizing beliefs and attitudes toward depression are needed. We developed stepwise strategies to promote counterstereotypic exemplars of people with depression and conducted an experiment (N?=?105) with a pretest–posttest control group design to examine effects of these strategies. Our results showed that implicit stigmatizing beliefs and attitudes were reduced more in the experimental group, in which the counterstereotypic strategies were implemented in addition to the provision of education regarding basic knowledge of depression, than in the control group, which received only education. 相似文献
9.
10.
Previous work suggests that there may be fundamental differences between compensatory stepping responses evoked by postural perturbation and visually cued “volitional” stepping (e.g., gait initiation). In contrast to visual cueing, postural destabilization evokes an array of sensory inputs that are intrinsically linked to the mobilization of rapid compensatory responses. The hypothesis examined in this study was that this fundamental difference would lead to distinct changes in the temporal characteristics of the stepping response. Six healthy young adults were instructed to step quickly in response to either visual cueing or anterioposterior platform motion. Both forward and backward stepping responses were characterized, using measures of vertical ground reaction force. A stereotypical temporal patterning of the stepping response occurred in both stimulus conditions and both directions of stepping, and anticipatory postural adjustments were evident in all trials. However, postural destabilization led to a more rapid initiation and execution of the temporal pattern, in comparison with visually cued responses. The most pronounced effect was seen in the duration of the response, which was reduced by a factor of two, with approximately proportional foreshortening of both the preparatory and swing phases. The results suggest that sensory information conveying a state of instability has a distinct influence on the characteristics of a subsequent stepping reaction. The persistence of the anticipatory postural adjustments suggests that the failure to see this element of the response in previous studies may reflect fundamental differences between volitional and unplanned compensatory stepping. 相似文献