Increases in language lateralization in normal children as observed using magnetoencephalography

Previous functional magnetic resonance imaging (fMRI) studies investigating hemispheric dominance for language have shown that hemispheric specialization increases with age. We employed magnetoencephalography (MEG) to investigate these effects as a function of normal development. In sum, 22 healthy children aged 7-16 years were investigated using two language tasks: a verb-generation (VG) task and a vowel-identification (VI) task. Significant hemispheric differences were found for both tasks in cerebral language areas using oscillatory MEG spectral analyses, confirming the MEG's ability to detect hemispheric specialization for language in children. Additionally, a significant increase of this lateralization as a function of age was observed for both tasks. As performance in the VI task showed no correlation with age, this increase seems to be unrelated to performance. These results confirm an increase in hemispheric specialization as a function of normal brain maturation.     

Reorganization of the cerebro-cerebellar network of language production in patients with congenital left-hemispheric brain lesions

Patients with congenital lesions of the left cerebral hemisphere may reorganize language functions into the right hemisphere. In these patients, language production is represented homotopically to the left-hemispheric language areas. We studied cerebellar activation in five patients with congenital lesions of the left cerebral hemisphere to assess if the language network is reorganized completely in these patients, i.e. including also cerebellar language functions. As compared to a group of controls matched for age, sex, and verbal IQ, the patients recruited an area not in the right but in the left cerebellar hemisphere. The extent of laterality of the cerebellar activation correlated significantly with the laterality of the frontal activation. We suggest that the developing brain reacts to early focal lesions in the left hemisphere with a mirror-image organization of the entire cerebro-cerebellar network engaged in speech production.     

Darstellung der Aktenlage

Ohne Zusammenfassung     

Psychometric properties of the d2 selective attention test in a sample of premature and born-at-term babies

The psychometric properties of the d2 Selective Attention Test are analyzed in two samples of premature ( n = 63) and born-at-term ( n = 78) children. The reliability coefficients (internal consistency) reached values of around .90. Principal components analysis revealed a three-factor structure, which accounts for 58% of the variance, and thus coincides with the number of factors presented in the manual of the Spanish adaptation of the test but not with their composition. Results suggest that the d2 test has adequate psychometric properties both for the global sample and for each sub-sample.     

Kann man die akute Gefährlichkeit schizophren Erkrankter erkennen?

Homicidal acts of schizophrenic persons get a lot of public attention and fuel fears about the dangerousness of the mentally ill. There is indeed a small subgroup of psychotics who are involved in violent acts in disproportionate amounts, especially in the case of co-morbid substance abuse. As most of these offenders were in psychiatric treatment beforehand, it has to be questioned whether their dangerousness could have been recognized and whether adequate intervention would have been possible. This paper describes the factors which can lead to a long-term increase in the risk of violent behaviour in schizophrenia, and also criteria which indicate acute dangerousness.     

Definitions need to be precise and consistent: A reply to Haslam with suggestions for the future

In his reply to our critique of research on self-humanizing, Haslam claims that we used a narrow definition of self-humanizing that ignored the evidence from the correlational research he and his colleagues have done. We disagree. First, we relied upon a definition of self-humanizing based upon comparative judgments that Haslam and colleagues have consistently used. Second, we were well aware of the correlational research he and his colleagues have done. We simply did not think, and do not think, these correlations verified the existence of self-humanizing as defined. In his reply, Haslam offered a new definition of self-humanizing that defines self-humanizing in terms of correlations between comparative judgments and ratings of how much traits reflect human nature. Although we believe this change represents some progress, numerous issues in the study of self-humanizing remain to be resolved. We offer some suggestions for future research on this important topic.