Recent Innovative Studies of Memory in Temporal Lobe Epilepsy

Investigations of patients with temporal lobe epilepsy continue to result in significant advancements in the neuroscience of human memory, as they have for over 50 years. Recent reviews describing the state of the art in the clinical neuropsychology of TLE generally have emphasized (1) lateralization of cognitive deficits and the material-specific model of memory and/or (2) the relationships among pre- and post-surgery performance on standardized measures of anterograde memory, demographic and epilepsy variables and neuroimaging, neuropathology, and neurosurgery data. As information continues to accumulate about the pattern of performance on standard laboratory memory tests and the implications of these data before and after anterior temporal lobectomy for the treatment of TLE, innovative assessment techniques also are increasingly being applied. This review focuses on English language publications that addressed selected novel topics in adult TLE memory research. These topics are: (1) remote memory; (2) accelerated forgetting or long term amnesia; and (3) lateral versus mesial temporal lobe contributions to memory.     

Who do you look like? Evidence of facial stereotypes for male names

The present research provides evidence that people use facial prototypes when they encounter different names. In Experiment 1, participants created face exemplars for fifteen common male names, subsets of which were endorsed as good examples by a second set of participants. These most typical faces were morphed to create face-name prototypes. In Experiment 2, participants matched one of the names to each of the prototype faces from Experiment 1. Participants’ matching choices showed convergence in naming the prototypes for many of the names. Experiment 3 utilized these same prototypes in a learning task designed to investigate if the face-name associations revealed in Experiment 2 impacted the learnability of the names. Participants learned face-name pairings that had a higher association (based on frequencies from Experiment 2) faster than pairings with a low association. Results suggest a more direct relationship between faces and names than has been previously proposed.     

The influence of intertrial interval food on extinction and devaluation in chain schedules

The authors exposed pigeons to 2 equal 3-link chains by using variable-interval schedules of reinforcement. An intertrial interval (ITI) bisected by free food separated the chains. After baseline training, the authors presented terminal links in a successive discrimination to devalue 1 terminal link: The authors reinforced responses to 1 terminal link and extinguished responses to the other. The authors then presented full chains in extinction, except that they continued to deliver free food during the midpoint of the ITI. There were 2 principal findings. First, across all extinction conditions, responding decreased but did not extinguish. Second, when extinction testing revealed a terminal link devaluation effect in the 3rd condition, responding to the initial link was affected, but not middle-link responding. Overall, the results suggested that ITI food presentations can exert a substantial effect on responding in 3-link chain schedules, and they appear to influence both the pattern of extinction and devaluation effects.     

Terrorism,Post-traumatic Stress,Coping Strategies,and Spiritual Outcomes

This mail survey measured post-traumatic stress symptoms, spiritual and non-spiritual coping strategies, and positive spiritual outcomes following the tragedies of 9/11/01 in a national, random sample of 1,056 Presbyterians. Respondents reported mild to moderate degrees of re-experiencing and hyper-arousal symptoms of post-traumatic stress, unrelated to location or knowing someone involved. People experiencing high stress used greater frequency and variety of both spiritual and non-spiritual types of coping strategies. Positive spiritual outcomes were remarkably related to positive spiritual coping strategies, in contrast to no association with negative coping. This study illustrates the significant degree of post-traumatic stress experienced with vicarious exposure and a wide spectrum of coping strategies used following the major terrorist attacks.

Patterns of brain-electrical activity during declarative memory performance in 10-month-old infants

This study of infant declarative memory concurrently examined brain-electrical activity and deferred imitation performance in 10-month-old infants. Continuous electroencephalogram (EEG) measures were collected throughout the activity-matched baseline, encoding (modeling) and retrieval (delayed test) phases of a within-subjects deferred imitation task. Infants were divided into two memory performance groups based on the exhibition of ordered-recall after a 24-h delay. Whereas no group differences were found in EEG collected during encoding, performance-group differences in EEG were present during retrieval. Infants who successfully displayed ordered-recall showed a pattern of increasing EEG from baseline to task at anterior temporal scalp locations, whereas infants showing no ordered-recall displayed no changes in EEG from baseline to task. These findings are discussed with respect to the biobehavioral developments underlying declarative memory abilities.     

The relationship between violence and youth suicide indicators among Asian American and Pacific Islander youth

The literature documents a relationship between interpersonal violence and suicide. One tool used to understand interpersonal violence is the Power Wheel, developed from clinical experience and originally used in domestic violence education. We examine the relationship between Teen Power and Control Wheel domains and suicidal indicators (seriously considered suicide, made a suicide plan, and attempted suicide) among Asian American and Pacific Islander high school students, in terms of both victimization and perpetration. Data from a 2007 survey of two multi-ethnic high schools on the island of O'ahu, Hawai'i were used. The survey assessed interpersonal youth violence and a multitude of risk and protective factors. It found that females were significantly more likely to seriously consider suicide and attempt suicide, compared to males. There were no statistically significant differences in seriously considering suicide, making a suicide plan, and attempting suicide by ethnic group, employment status, or hours worked per week. Using the Wheel, we found that all dimensions for victimization and perpetration were associated with the three suicidal indicators. However, the magnitude of this association was dramatically higher for victims than for perpetrators. School- and healthcare-based prevention strategies should ensure that both suicide and violence intervention components are addressed. Professionals who work with youth should be trained to feel comfortable, confident, and competent in discussing suicide and violence, and be willing and capable to assess and intervene.     

Striving for a culturally responsive process in training health professionals on Asian American and Pacific Islander youth violence prevention

The quality of youth violence prevention practice is dependent on the quality of education and training of professionals who will care for disadvantaged and/or underserved youth. The authors propose that culturally responsive youth violence prevention curricula, focused on Asian Americans and Pacific Islanders, should: 1) target institutions that train health professionals likely to serve Asian Americans and Pacific Islanders; 2) promote the professional development of Asian American and Pacific Islander students and enhance all students' comfort in addressing behavioral, social, and cultural concerns; 3) cover specific issues relevant to Asian Americans and Pacific Islanders, including the role of acculturative stress, socioeconomic hardship, and other risk factors that may account for mental health disparities; and 4) continuously engage researchers, educators, and community stakeholders in cooperatively and creatively applying new knowledge to clinical challenges. The authors summarize resources for youth violence prevention education that have been used for training healthcare professionals in a multicultural context.     

Making treatment effect inferences from multiple-baseline data: The utility of multilevel modeling approaches

Multiple-baseline studies are prevalent in behavioral research, but questions remain about how to best analyze the resulting data. Monte Carlo methods were used to examine the utility of multilevel models for multiplebaseline data under conditions that varied in the number of participants, number of repeated observations per participant, variance in baseline levels, variance in treatment effects, and amount of autocorrelation in the Level 1 errors. Interval estimates of the average treatment effect were examined for two specifications of the Level 1 error structure (σ² I and first-order autoregressive) and for five different methods of estimating the degrees of freedom (containment, residual, between—within, Satterthwaite, and Kenward—Roger). When the Satterthwaite or Kenward—Roger method was used and an autoregressive Level 1 error structure was specified, the interval estimates of the average treatment effect were relatively accurate. Conversely, the interval estimates of the treatment effect variance were inaccurate, and the corresponding point estimates were biased.