d-Amphetamine-chlorpromazine antagonism in a food reinforced operant

Dose effect curves for d-amphetamine and chlorpromazine were obtained with rats on a milk reinforced FR 10 schedule. A dose of d-amphetamine (2.5 mg/kg, i.p.) which completely suppressed all responding for 60 min was administered simultaneously (concomitant with the pretreatment times) with various doses of chlorpromazine. The d-amphetamine-induced cessation of responding was removed by several of the doses of chlorpromazine with maximal antagonism occurring at a dose of 1.5 mg/kg i.p. This dose of chlorpromazine, when administered independently, produced no observable side effects and showed no effect on the FR 10 schedule. One animal appeared to develop tolerance to the repeated dosages of d-amphetamine.     

The effect of prior recall on multiple response recognition

Certain investigators have found that recognition is impaired when a recall test is interpolated during the retention interval. One possible explanation of this finding is that interpolated recall leads subjects to employ a more stringent recognition criterion. In the two experiments reported here, the influence of the recognition criterion was eliminated by using a multiple-response test requiring subjects to rank a recognition list consisting of old and new items. Nevertheless recall impaired subsequent recognition in both experiments, the effect being most marked for lowly ranked items. The recognition test in the first experiment was carried out in two stages. This made possible a direct examination of whether recall has an effect on the recognition criterion. No evidence for such an effect was obtained. Other ways in which recall may affect the recognition criterion are discussed.     

Some physical determinants of viewing time under three instructional sets

One-hundred fifty human Ss viewed 32 patterns under neutral (N), pleasingness (P), or interestingness (l) instructional sets. An analysis of variance indicated that patterns with larger areas were viewed longer than patterns with smaller areas under all conditions; however, this effect was more pronounced under the P and I conditions than under the N condition. Patterns containing 9-sided shapes were viewed longer than those containing 3-sided shapes under the N and I conditions, while the reverse was true for the P condition.