Memory and brain volume in adults prenatally exposed to alcohol

The impact of prenatal alcohol exposure on memory and brain development was investigated in 92 African-American, young adults who were first identified in the prenatal period. Three groups (Control, n=26; Alcohol-related Neurodevelopmental Disorder, n=36; and Dysmorphic, n=30) were imaged using structural MRI with brain volume calculated for multiple regions of interest. Memory was measured using the Verbal Selective Reminding Memory Test and its nonverbal counterpart, the Nonverbal Selective Reminding Memory Test, which each yielding measures of learning and recall. For both Verbal and Nonverbal Recall and Slope, linear trends were observed demonstrating a spectrum of deficits associated with prenatal alcohol exposure. Dysmorphic individuals performed significantly poorer than unexposed controls on 5 of 6 memory outcomes. Alcohol-exposed individuals demonstrated significantly lower total brain volume than controls, as well as lower volume in a number of specific regions including hippocampus. Mediation analyses indicated that memory performance associated with effects of prenatal alcohol exposure was mediated from dysmorphic severity through hippocampal volume, particularly right hippocampus. These results indicate that the association between the physical effects of prenatal alcohol exposure and deficits in memory are mediated by volumetric reduction in specific brain regions.     

Expressivism and plural truth

Contemporary expressivists typically deny that all true judgments must represent reality. Many instead adopt truth minimalism, according to which there is no substantive property of judgments in virtue of which they are true. In this article, I suggest that expressivists would be better suited to adopt truth pluralism, or the view that there is more than one substantive property of judgments in virtue of which judgments are true. My point is not that an expressivism that takes this form is true, but that it more readily accommodates the motivations that typically lead expressivists to their view in the first place.     

Factor structure of the Wide Range Assessment of Memory and Learning (WRAML) in children with insulin dependent diabetes mellitus (IDDM).

Maximum likelihood confirmatory factor analysis was performed with the Wide Range Assessment of Memory and Learning (WRAML) for a clinical sample of 246 children with insulin-dependent diabetes mellitus (IDDM). Consistent with previous literature examining the factor structure of the WRAML, findings supported the validity of a three-factor model including Verbal Memory, Visual Memory, and Attention/Concentration (AC) factors for this clinical sample. However, in contrast to previous factor analytic research, results also supported the validity of an alternative two-factor model consisting of a combined modality Memory/Learning (ML) factor and an AC factor. While the results suggest that the three-factor solution may provide an adequate characterization of memory and learning in the majority of this sample of children with IDDM, it appears that certain groups of children with IDDM, particularly those children with early disease onset and those who experience hypoglycemic seizures, may exhibit a specific profile of differences that may result in a lack of differentiation between the verbal and visual modalities.     

Exploring Positive Learning Experiences in the Context of Practical Theological Education

Abstract. This article presents findings from an empirical study exploring student and teacher perspectives on positive learning experiences in practical theological education. Forty‐five students and twenty teachers were interviewed in focus groups in four educational institutions delivering programs in practical theology. The findings indicated that students valued practical theological education when it enabled them to think critically in relation to their personal or professional experience, and that students valued tutors, their peers and a flexible curriculum design in promoting this kind of learning. There was a high correlation between students’ views of positive learning experiences and what tutors perceived as important qualities that they hoped their students would develop. Difficulties associated with the students’ lack of clarity about the learning process and the tensions between academic and professional contexts are also discussed.     

Managing antidepressants in primary care: physicians' treatment modifications

To examine antidepressant management practices in primary care, patients (N = 148) given an antidepressant for at least one month completed the Beck Depression Inventory (BDI-II), the Patient Health Questionnaire-9 (PHQ-9), and a demographic survey. Participants' mean age was 50.7 yr. and 80% were women. Patients' charts indicated whether physicians had made changes to prescribed antidepressants or dose either 6 wk. before or 6 wk. after study entry. For the 87% of participants whose depression status could be determined, 10% met dysthymic disorder criteria and only 33% had had a medication change in the previous month. Major depressive disorder occurred in 37% but only 18% had had a medication change. Co-existing dysthymic disorder and major depressive disorder were diagnosed in 34%, with 24% receiving a medication change. Participants not receiving a medication change had mean BDI-II scores indicating moderate depression. Lack of antidepressant adjustment suggests physicians may need to monitor depressive symptoms closely using protocols and prompts.     

A Psychometric Analysis of the Revised Child Anxiety and Depression Scales—Parent Version in a School Sample

The Revised Child Anxiety and Depression Scale—Parent Version (RCADS-P) is a parent-report questionnaire of youth anxiety and depression with scales corresponding to the DSM diagnoses of separation anxiety disorder, social phobia, generalized anxiety disorder, panic disorder, obsessive-compulsive disorder, and major depressive disorder. The RCADS-P was recently developed and has previously demonstrated strong psychometric properties in a clinic-referred sample (Ebesutani et al., Journal of Abnormal Child Psychology 38, 249–260, 2010b). The present study examined the psychometric properties of the RCADS-P in a school-based population. As completed by parents of 967 children and adolescents, the RCADS-P demonstrated high internal consistency, test-retest reliability, and good convergent/divergent validity, supporting the RCADS-P as a measure of internalizing problems specific to depression and five anxiety disorders in school samples. Normative data are also reported to allow for the derivation of T-scores to enhance clinicians’ ability to make classification decisions using RCADS-P subscale scores.     

Anger,aggression, risky behavior,and crash-related outcomes in three groups of drivers

High anger drivers who acknowledged problems with driving anger and were interested in treatment were compared to high and low anger drivers who did not acknowledge problems with driving anger or want treatment. Although high anger drivers who acknowledged problems reported greater anger on two measures than high anger drivers who did not acknowledge problems, both high anger groups tended not to differ from one another and were more frequently and intensely angered when driving, reported more aggressive and less adaptive/constructive forms of expressing anger while driving, engaged in more aggressive and risky behavior on the road, and experienced more of some accident-related outcomes than low anger drivers. High anger groups did not differ from each other, but reported more trait anxiety and anger and more outward negative and less controlled general anger expression than the low anger group. The two groups of high anger drivers, however, require different types of interventions given their state of readiness for driving anger reduction. Results were also interpreted as supportive of the state-trait model of anger and construct validity of the Driving Anger Scale.