Intracerebroventricular effects of angiotensin II on a step-through passive avoidance task in rats

A wealth of evidence indicates that angiotensin II (Ang II) is involved in learning and memory. However, the precise role of this peptide in these cognitive processes is still controversial, with data indicating either an inhibitory or an enhancing action. The present study was designed to further investigate the effects of intracerebroventricular injections of Ang II (0.5, 1 or 3nmol/5microl) on a step-through passive avoidance task in male adult Wistar rats. When administered pretraining, Ang II did not affect the acquisition of passive avoidance, but markedly improved avoidance performance when given before the retrieval test. The latter effect was observed in retest sessions performed up to 72h after training. Administration of the peptide five minutes after training impaired retention of inhibitory avoidance. Therefore, Ang II may exert opposite effects on passive avoidance memory according to its interference with brain mechanisms leading to the storage or retrieval of this aversively motivated task.     

Bringing actors together around large-scale water systems: Participatory modeling and other innovations

Conclusion The five areas of innovation found in the three case studies have brought actors together in new ways around water management strategies. We paid special attention to the role of participatory modeling, because it has been able to generate new policy options. For such complex and often deadlocked water management issues, new options are at a premium. The cases demonstrate that participatory modeling efforts are a key part of successfully addressing these major water management issues faced in the U.S. as well as elsewhere. Recent publications include Ecology, Engineering and Management: Reconciling Ecosystem Rehabilitation and Service Reliability (with Emery Roe; Oxford: Oxford University Press). Current research interest include the reliability of critical infrastructures (such as electricity, water, telecommunications and the internet) and the development of methods to recast the intractable policy issues. Since 1999, he has been a Visiting Scholar at the University of California, Berkeley and Mills College, Oakland. where he teaches and directs research in the application of economic theory and systems analysis methods to the solution of environmental and regional water resources problems. He has authored numerous articles and book chapters, served on various committees of the National Research Council of the National Academy of Sciences, and was a U.S. member of an advisory committee for the International Institute for Applied Systems Analysis (IIASA) in Laxenburg, Austria. Emery Roe has published widely on science, technology and environmental controversies, including the debates over large technical systems, sustainable development, and ecosystem management. His books include Narrative Policy Analysis (Duke University Press, 1994), Taking Complexity Seriously: Policy Analysis, Triangulation and Sustainable Development (Kluwer, 1998), Except-Africa: Remaking Development, Rethinking Power (Transaction, 1999), and Ecology, Engineering and Management: Reconciling Ecosystem Rehabilitation and Service Reliability (with Michel van Eeten; Oxford: Oxford University Press).     

Kunsttherapie in der Behandlung chronifizierter Schmerzpatienten

Integrated in the evaluation of an innovative concept of art therapy a questionnaire for the measurement of effects and progression of art therapy (FB-KT) was developed and evaluated. The study was performed as part of a multidisciplinary pain therapy on patients with somatization disorders at the day-care pain clinic of the University of Münster. It was a twelve month lasting study, which started in November 1998 and finished in November 1999. The dimensions of the questionnaire were defined by a sample testing of 108 people. To validate the scales of the FB-KT four relevant standardised instruments in pain therapy were used. The results show, that the quality criteria of the questionnaire can be described as satisfactory to excellent. The results further demonstrate that the FB-KT shows therapeutic effects in the dimensions of emotional experience just as clearly as other standardised instruments do. In addition, FB-KT gives informations about experiences during the therapy sessions.     

The dimensions of stage theories

Stage theories are commonly used to represent the structure of cognitive processes in the domains of cognitive processing and cognitive development. Hierarchical unidimensional theories consisting of a single sequence of stages through which development proceeds in one direction only have predominated. However, a review of stage theories revealed that a two-dimensional, interactive (multidimensional) structure is warranted. Particularly in the area of cognitive development, results of research have supported subdivision of the stages of prominent unidimensional theories. Following this trend a small number of theorists have developed multidimensional theories, most of which consist of a sequence of stages in which each stage contains a number of subsidiary stages or levels. The emergence of a similar trend in other domains is examined, and the prospects of using an existing multidimensional framework to enable future comparisons and integration of different stage theories is explored.     

The Adaptation of Patients During the Hospitalization Period of Bone Marrow Transplantation

A longitudinally study was conducted among 42 bone marrow transplantation (BMT) patients to investigate the association between pretransplant psychosocial variables and psychophysiological outcomes during the immediate convalescence period. Family relationships (cohesion, expressiveness, and conflict) and coping resources (cognitive, social, emotional, spiritual/philosophical, and physical resources) were assessed on the admission day (Day –7 Time 1). Data on psychological distress and pain intensity were obtained on Day +7 (Time 2) and Day +14 (Time 3). The average scores at Times 2 and 3 were computed to indicate the overall adjustments of the patients during the hospitalization period after the day of actual transplant (Day 0). It was shown that higher expressiveness family relationships and higher resources to cope effectively with stressful situations were associated with less psychological distress during the above period. Both pretransplant psychosocial variables were not associated with pain intensity during hospitalization. Allogeneic transplant patients reported higher pain intensity than did autologous transplant patients. Psychological distress and pain intensity were positively correlated with each other. Our findings show that pretransplant family relationships and coping resources associate moderately with psychological distress during the immediate convalescent period of BMT. The present findings support the family-centered approach to BMT care and provide a scientific basis for pretransplant psychosocial interventions.     

Interpersonal behaviors and friendship in a Chinese culture

This research is designed to assess the links between interpersonal behaviors and relationship development. A measure of friendship, labeled 'communion', was developed that focused exclusively on the characteristics of the relationship itself. It was hypothesized that greater use by both parties of behaviors promoting the interests of the other, 'beneficence', and of behaviors respecting the rights of the other, 'restraint', would result in greater communion between the roommates by the end of their first 6 months together. Both dimensions of behavior proved to be related to communion, although beneficence by both parties was relatively stronger than restraint. These findings were discussed in terms of other types of relationships where there is less freedom of involvement and greater hierarchy.     

Lorenz Curves: A New Model for the Distribution of Psychiatric Services

The growth of child and adolescent psychiatric services based on the wraparound philosophy raises new questions for medical directors, investigators, and clinicians interested in improving quality of care and outcomes. Typically, quality improvement studies have focused on standardizing care and decreasing variation while community based services following a wraparound model are by definition individualized. To date, little information on how to evaluate such services in a managed care environment has been available. We present one option for evaluating the distribution of medical services and the extent to which providers individualize services for children with severe emotional disorders. Specifically, we (a) review the philosophy and goals of wraparound services, (b) introduce the Lorenz curve as a tool for determining the degree of inequality in service distribution at a given institution, and (c) present a case study on the use of Lorenz curves by a Medicaid Behavioral Health Organization in profiling behavioral providers.     

Well-being of mothers of children with mental retardation: An evaluation of the Double ABCX model in a cross-cultural context

The present study was designed to compare the psychological well-being of mothers of children with mental retardation in the USA and Korea. The Double ABCX model of stress proposed by McCubbin and Patterson (1983) was evaluated for the two national groups. Thirty-eight American and 40 Korean mothers participated in the home-visit interview. The path models in the present study partially supported the ABCX model, but different path models for the two national groups provided important explanations for the well-being of mothers from the two nations. The cause of stress for the American mothers was specific to the individual variables. For Korean mothers, cultural values that carry social influence were more strongly associated with their attitudes towards the child and their experience of stress.