视觉刺激探测的警觉性注意特征初探

采用"预警提示-目标探测"范式,对视觉刺激探测的警觉性注意特征进行初步探索。实验一表明,随着预备到目标刺激的时间间隔(interstimulus interval,ISI)变化,固定位置上探测目标刺激的速度也随之变化,并且对大概率刺激的探测更快,表现出了警觉性注意的稳定性和选择性特征。实验二进一步考察了目标刺激在不同ISI和不同空间位置的情况,除发现与实验一相似的结果以外,被试探测目标刺激的速度随注意视角增大而下降,表现出了警觉性注意的集中性特征。     

Mechanism of isoflavone aglycone's effect on cognitive performance of senescence-accelerated mice

This study investigated the effect of isoflavone aglycone (IA) on the learning and memory performance of senescence-accelerated mice, and explored its neural protective mechanism. Results showed that SAM-P/8 senescence-accelerated mice treated with IA performed significantly better in the Y-maze cognitive test than the no treatment control (P<0.05). The cortex AchE activity, serum SOD and GSH-Px activities were notably higher (P<0.05). MDA concentration and the β-secretase activity in the hippocampal tissue were both lower (P<0.05). Additionally, the number of hippocampal neurons was increased and cell morphology was significantly improved. Data suggested that IA could indirectly increase concentration of the cholinergic neural transmitter Ach through regulation of AchE, therefore improving the central cholinergic function and enhancing the learning and memory ability. By reducing the β-secretase activity, IA could decrease the formation and deposition of insoluble Adebris, relieve the resulted toxicity and damage to neurons, and thereby effectively protect the nervous system.     

相似性、相似性组合及元认知监控对问题类比推理的影响研究

以改编Holyoak等设计的“汇聚问题”为实验材料,同时自编元认知监控问卷测试被试的元认知监控水平,考察相似性的不同水平,源问题个数,两个源问题情境下源问题的组合方式以及被试的元认知监控水平对类比迁移的影响。结果表明,一个源问题呈现情境下,源、靶问题不同的相似性水平差异显著,表面相似性显著促进类比迁移;两个源问题呈现情境下,源问题的不同组合方式差异显著;无论是呈现一个源问题,还是呈现两个源问题,元认知监控差异均显著,类比迁移主要是控制性加工;源问题个数差异显著。     

客体工作记忆任务中大脑皮层活动的记忆负荷效应

利用128导事件相关电位技术,采用延迟匹配任务的实验范式,测查了20名正常被试完成不同负荷客体任务时的皮层慢电位（slow cortical potentials,简称sp成分）,实验发现：背侧前额叶在刺激呈现后的700ms到1400ms出现记忆负荷效应,高负荷任务诱发的sp成分显著负于低负荷任务;低负荷任务诱发的sp成分在左前额区（500~1800ms）、左前额-中央区（700~1800ms）、左中央-顶叶区（1000~1400s和1800~4800ms）、右前额区（1800~4800ms）和右前额-中央区（1400~4800ms）显著负于高负荷任务,出现记忆负荷效应,但这种负荷效应在左右大脑半球所反映的心理意义可能不同     

The behavioral activation for depression scale-short form: development and validation

Following a landmark component analysis of cognitive therapy by Jacobson and colleagues (1996), there has been renewed interest in behavioral activation (BA) treatments for depression. The Behavioral Activation for Depression Scale (BADS) was developed to measure when and how clients become activated over the course of BA treatment. Multiple studies have provided initial support for the BADS but have also identified several potential problems. Four studies were conducted in order to develop and provide initial evaluation of a short form of the BADS that addresses these concerns. In Study 1, an exploratory factor analysis was conducted on existing data using the original BADS in order to identify items to retain for the short form. In Study 2, these items were administered to a new sample of college students with elevated depressive symptoms and were analyzed with exploratory and confirmatory factor analyses. Study 3 examined the predictive validity of the BADS-SF by examining the BADS-SF and depression scores in relation to activity tracking and reward-value ratings over the course of 1 week. Study 4 examined BADS-SF data over the course of BA treatment for two clients using cross-lagged panel correlations. With one client, changes in BADS-SF scores led changes in depression scores by 1 week, whereas with the other client changes in BADS-SF and depression scores occurred concurrently. These studies resulted in a nine-item scale that demonstrated good item characteristics as well as acceptable internal consistency reliability, construct validity, and predictive validity.     

检验项目功能差异的两类方法-CFA和IRT的比较

目前在验证性因素分析(CFA)和项目反应理论(IRT)两个领域,都有一些检验方法来识别项目功能差异(DIF)。该文主要针对单维的多级计分项目,分别介绍CFA和IRT检测DIF的方法,并进行二者的比较。     

浅谈恙虫病的几点认识

恙虫病是自然疫源性急性传染病.通过恙虫病医疗实践,谈几点个人认识:恙虫病流行与该疫源地区鼠类活动有关;恙虫病疫源地会因气候变化而变更;重视恙虫病准确而及时诊断,尽量减少病人疾苦;恙虫病立克次体对人单核-吞噬细胞系统有特别的亲嗜性与专性细胞内寄生,是其临床病理基础;用氯霉素联合双黄连治疗恙虫病可获满意效果.     

The attribution of attention: 9-month-olds' interpretation of gaze as goal-directed action

The current study distinguishes between attributions of goal-directed perception (i.e. attention) and non-goal-directed perception to examine 9-month-olds' interpretation of others' head and eye turns. In a looking time task, 9-month-olds encoded the relationship between an actor's head and eye turns and a target object if the head and eye turns were embedded in a sequence of multiple, variable actions with equifinal outcomes, but not otherwise. This evidence supports the claim that infants of this age may attribute perception, at least goal-directed perception, to others and undermines arguments that gaze-following at this age consists only of uninterpreted reflexes. The evidence also suggests alternative interpretations of the typical errors infants make in standard gaze-following procedures. Implications for infants' understanding of perception and attention in both human and non-human agents are discussed.     

产业融合背景下流通业培育核心竞争能力的再思考

本文根据演化论思想,分析了新经济时代的本质特征及其对我国流通企业的影响,在此基础提出了我国流通企业的核心竞争能力的构成要素,并进一步指出了培育核心竞争能力的实现途径.     

Neural correlates of Traditional Chinese Medicine induced advantageous risk-taking decision making

This fMRI study examined the neural correlates of the observed improvement in advantageous risk-taking behavior, as measured by the number of adjusted pumps in the Balloon Analogue Risk Task (BART), following a 60-day course of a Traditional Chinese Medicine (TCM) recipe, specifically designed to regulate impulsiveness in order to modulate risk-taking behavior. The 14 participants recruited for this study were randomly assigned to the experimental and control groups and the TCM recipe (Panax, 520 mg; Astragalus membranaceous Bunge, 520 mg; Masnetitum, 840 mg; Ostrea gigas Thumb, 470 mg; Thinleaf Milkwort Root Radix Polygalae, 450 mg; and Os Draconis, 470 mg) was administered, as a diet supplement, to the seven participants in the experimental group. The neural activity of the two groups was monitored by a 3T MRI scanner, before and after the 60-day treatment. Associated with the improved advantageous risk-taking behavior seen in the experimental group, significantly stronger blood oxygenation level dependent (BOLD) responses were observed in the bilateral dorsolateral prefrontal cortex (DLPFC), left putamen, left thalamus, right insula, and right anterior cingulate cortex (ACC), regions which have previously been reported as being involved in risk-taking decision making. The effect of the TCM in improving advantageous risk-taking decision making appears to have been related to the enhanced efficiency of the cognitive affective system, the PFC–ACC–insula–striatum network, which functions to inhibit impulsiveness, to sensitize reward-related information, and to allow the opportunity, during risk estimation, to evaluate potential gains and losses. The findings of this study suggest that interventions acting on factors modulating risk-taking decision making could have a beneficial effect in terms of optimizing risk-taking behavior.