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111.
We present a review of the literature on Primary Progressive Aphasia (PPA) together with the analysis of neuropschychological and neuroradiologic profiles of 42 PPA patients. Mesulam originally defined PPA as a progressive degenerative disorder characterized by isolated language impairment for at least two years. The most common variants of PPA are: 1) Progressive nonfluent aphasia (PNFA), 2) semantic dementia (SD), 3) logopenic progressive aphasia (LPA). PNFA is characterized by labored speech, agrammatism in production, and/or comprehension. In some cases the syndrome begins with isolated deficits in speech. SD patients typically present with loss of word and object meaning and surface dyslexia. LPA patients have word-finding difficulties, syntactically simple but accurate language output and impaired sentence comprehension. The neuropsychological data demonstrated that SD patients show the most characteristic pattern of impairment, while PNFA and LPA overlap within many cognitive domains. The neuroimaging analysis showed left perisylvian region involvement. A comprehensive cognitive, neuroimaging and pathological approach is necessary to identify the clinical and pathogenetic features of different PPA variants.  相似文献   
112.
Studies of semantic impairment arising from brain disease suggest that the anterior temporal lobes are critical for semantic abilities in humans; yet activation of these regions is rarely reported in functional imaging studies of healthy controls performing semantic tasks. Here, we combined neuropsychological and PE T functional imaging data to show that when healthy subjects identify concepts at a specific level, the regions activated correspond to the site of maximal atrophy in patients with relatively pure semantic impairment. The stimuli were color photographs of common animals or vehicles, and the task was category verification at specific (e.g., robin), intermediate (e.g., bird), or general (e.g., animal) levels. Specific, relative to general, categorization activated the antero-lateral temporal cortices bilaterally, despite matching of these experimental conditions for difficulty. Critically, in patients with atrophy in precisely these areas, the most pronounced deficit was in the retrieval of specific semantic information.  相似文献   
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Jana Sawicki uses the work and methods of Foucault to explore the possibility of a politics of difference. I argue that Foucault may help us overcome some forms of dogmatism inherited from men's political philosophy of the past, but Foucault is otherwise useless, or worse: misleading. Because Sawicki presents a politics of diversity among women regardless of, and independent from, a politics of sexual difference, I believe Foucault is misleading.  相似文献   
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The Psychological Record - Exposing rats to the predator odor of trimethylthiazoline (TMT), obtained from the red fox, was compared to exposure to the novel control odor of citronella. In...  相似文献   
117.
The incremental value of character strengths in the prediction of resilience, after the effects of other well-known resilience-related factors (i.e. positive affect, self-efficacy, optimism, social support, self-esteem, life satisfaction) and sociodemographic variables are accounted for, is examined. Using a cross-sectional design, participants (N = 363 adults) completed online measures of character strengths, resilience, and resilience-related factors. A principal component analysis of character strengths was conducted and five factors were extracted, which could be interpreted as emotional, interpersonal, intellectual, restraint, and theological strengths. All strengths factors, except theological strengths, yielded significant positive correlations with resilience. A hierarchical regression showed that strengths predicted an additional 3% of the variance in resilience over and above sociodemographic variables, positive affect, self-efficacy, optimism, social support, self-esteem, and life satisfaction. Emotional strengths and strengths of restraint were significant positive predictors. Implications, limitations, and future research are discussed.  相似文献   
118.
Public discourse in Western countries on the 2014 Ebola epidemic provided a unique natural opportunity to study the relationship between a disease's sociocultural representation and health policy support. Our main prediction stated that among Western citizens, support for restrictive health policies (e.g., mandatory quarantining) would be determined more through preexisting prejudice towards African immigrants than fears of Ebola infection. A questionnaire study with time‐lagged measurement of predictor and criterion variables employing a German sample (N = 218) that was heterogeneous in terms of gender, age, profession, political orientation, and income level provided clear support for this assumption. Although variables related to fear‐of‐infection were significant predictors, prejudice‐related variables explained several times more variance in participants’ support for restrictive policies. Moreover, the degree to which participants adopted prevalent beliefs regarding the sociocultural origins of Ebola (e.g., eating bushmeat) further intensified the impact of prejudice‐related variables.  相似文献   
119.
Temporality is a fundamental dimension of each narrative process of meaning making. In fact, the narration constructs and organizes temporal frames that connect one's own experiences. From this point of view, oncological illness is experienced as a traumatic experience that interrupts the sense of continuity of one's own life, resulting in the configuration of different temporal frames, which are not always able to support the processes of elaboration of this experience. The aim of this article is to explore the way the modal verbal predicates (must, can, will, know) are organized and work in relation to the representation of time in narrations of cancer patients. The modal verbal predicates—introducing the meanings of possibility, knowledge, will, desire, duty, need, or ability—allow us to organize the relationship between the subject, action, and context. Six narrations of cancer experience were analyzed—one for each time frame (linear, circular, fragmentary, static, cyclic, and spiral) proposed by Brockmeier (2000)—by means of quali-quantitative analysis of the use of modal verbs. Narrations show specific modal positioning: dispersion, plasticity, focusing, rigidity, and poverty. It is possible organize them along a continuum from plasticity to rigidity. The modal plasticity is the capacity to reconfigure a new temporal relation between subject and context, whereas modal rigidity shows a repetition of a specific and same modality in connecting subject and context. This preliminary research allows us to reflect about some possible clinical implications to support and foster processes of meaning making of cancer conditions.  相似文献   
120.
This paper is an empirical research based on observational methodology. It is an idiographic research with a mixed observational design of low intervention, of the following type: monitoring/nomothetical/multidimensional. We used a tool created in situ for the systematic multidimensional register of the complex occurrence of several types of behavioural events in real time, which combines the format of field investigation with the system of categories. The reliability of the observation tool is obtained through the researcher-observer's agreement with him- or herself. Our aim is to study the social relationships between first-grade peer students in a multicultural context. We present some structures of seeking social closeness, help and cooperation among children of similar and different cultures, which were discovered through the detection and analysis of temporal patterns of the interactive situation of boys and girls who were observed during their academic and leisure activities in the natural context of their school.  相似文献   
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