The cortisol awakening response in caregivers of schizophrenic offspring shows sensitivity to patient status

Abstract

Taking care of offspring during a prolonged period of time is probably one of the most stressful life experiences for parents. The present study compares the cortisol awakening response (CAR) in 38 long-term caregivers (mothers and fathers of schizophrenic relatives) with a control group of 32 non-caregivers. Factors such as general stress, caregiver burden, patient severity, and institutionalization were studied. Although a blunted CAR was observed in caregivers in comparison with controls, this difference was not significant. Among caregivers, the absence of institutionalization for the patient is associated with a lack of CAR in caregivers in comparison with caregivers of institutionally supported patients. General stress, caregiver burden, and patient severity themselves did not favor significant changes in CAR. CAR shows greater sensitivity to institutional support than patient severity and perceived stress. Further research is needed to explain the impact of these factors on health and the psychological factors involved.     

Trajectories of Experience of Real Life Events. A Semiotic Approach to the Dynamics of Positioning

This paper is devoted to the study of experience as a semiotic process of constructing the personal meaning of the situation lived. Its main purpose is to devise a semiotic methodology capable of describing and explaining the dynamics of positioning when facing personal lived experiences in real life contexts. Twenty four young adults were exposed to a simulated conflict and then asked to write a narrative of their understanding of the incident and a self-report of their personal experiences. Results show how narratives and trajectories of experience present different forms in each participant, which could be related to: a) the understanding of the situation lived and the position taken regarding the conflict; and b) the position each participant takes regarding the reports they had to produce for the researchers. The incorporation of reflexivity into the applied method allows identification of how the dynamics of double positioning leave traces in the records produced.     

RECRIMINATION IN THE ANALYTIC SITUATION: A HYPOTHESIS ABOUT ITS INFLUENCE ON PSYCHOANALYTICAL GROUPS

This paper deals with certain distortions in communication generated by mutual recrimination that is the result of disturbances in the ideal agencies of both parties. Although the ideal ego, superego and ego ideal participate equally in reproach, it is the latter which is the most decisive. In clinical experience, recrimination may easily colour the analytic dialogue. In such cases, interpretation loses its sense of clarification and another type of dialogue replaces it. There, words are used to take possession of the other, for its autonomy is a threat to the static character of the pathology of mourning. The problem of recrimination has also tainted the development of psychoanalysis, to the point of disrupting the process of discovery itself. This paper deals with repercussions in the psychoanalytic movement and also in the elements that constitute its structure. Finally, different variations and disturbances in the psychoanalytic ideal are considered, as well as the involvement of the psychoanalytic institution in preserving or transforming the ideal. Here the importance of institutions and institutional ideals is emphasised. Finally, we suggest that ideals either encourage or hinder the working through of individual and collective mourning.     

Does “whole-word shape” play a role in visual word recognition?

To analyze the impact of outline shape on visual word recognition, the visual pattern of the stimuli can be distorted by size alternation. Contrary to the predictions of models that rely on outline shape (Allen, Wallace, & Weber, 1995), the effect of size alternationwas greater for low-frequency words than for high-frequency words in a lexical decision task (Experiment 1). In Experiment 2, the effect of case type (lowercase vs. UPPERCASE) occurred for low-frequency words, but not for high-frequency words. The effect of neighborhood size was remarkably similar in the two experiments. The results can be readily explained in the framework of a resonance model (Grossberg & Stone, 1986), in which a mismatch between the original sensory pattern and the abstract orthographic code slows down the formation of a stable percept.     

Effects of chronic administration with high doses of testosterone propionate on behavioral and physiological parameters in mice with differing basal aggressiveness

The effects of testosterone propionate, an anabolic‐androgenic steroid, on the behavior displayed during a social encounter by gonadally intact male mice were investigated. Animals were distributed into three groups according to their attack latency in a pre‐screening test (high‐, moderate‐, and low‐ attacking mice) and each group received weekly injections of 60 or 120 mg/kg of testosterone or sesame oil for 10 weeks. Behavioral tests were then carried out. Afterwards, organs were weighed and blood samples collected in order to obtain hormonal data. Treatment had a differential impact on attack in the three groups of animals. Only the high‐attacking testosterone‐treated mice showed lower total duration of attack than their controls. Those that received 60 mg/kg spent more time exhibiting exploratory behaviors. As an index of the anabolic activity of the drug, all testosterone‐treated mice had heavier kidneys and, as an index of the androgenic activity of testosterone propionate, they had heavier seminal vesicles, lighter testes, and showed higher testosterone levels in a dose‐dependent way than their controls. Hence, the effect of treatment on peripheral physiological parameters was similar in all three groups whereas behavioral effects differed depending on basal aggressiveness, considered a characteristic of coping style. Aggr. Behav. 29:173–189, 2003. © 2003 Wiley‐Liss, Inc.     

Is IQ in Childhood Associated with Suicidal Thoughts and Attempts? Findings from The Mater University Study of Pregnancy and Its Outcomes

This study explores associations of IQ at age 14 with adult symptoms of suicidal thoughts and attempts at age 21. Analysis was based on the Mater University Study of Pregnancy and its outcomes, an Australian prospective birth cohort study started in Brisbane Australia in 1981. We assessed associations with suicide thoughts, plans, and attempts. We used two measures of IQ: the Raven's Standard Progressive Matrices and the Wide Range Achievement Test. In multivariable analyses, there was an inverse association between Raven's IQ and suicide thoughts, plans, and attempts, but no strong evidence of an association between the WRAT3 and the three suicidal items. Specific aspects of intelligence may be associated with suicidal thoughts, plans, and attempts.     

Electric source localization adds evidence for task-specific CNVs

This study was an attempt to replicate recent magnetoencephalographic (MEG) findings on human task-specific CNV sources (Basile et al., Electroencephalography and Clinical Neurophysiology 90, 1994, 157-165) by means of a spatio-temporal electric source localization method (Scherg and von Cramon, Electroencephalography and Clinical Neurophysiology 62, 1985, 32-44; Scherg and von Cramon, Electroencephalography and Clinical Neurophysiology 65, 1986, 344-360; Scherg and Berg, Brain Electric Source Analysis Handbook, Version 2). The previous MEG results showed CNV sources in the prefrontal cortex of the two hemispheres for two tasks used, namely visual pattern recognition and visual spatial recognition tasks. In the right hemisphere, the sources were more anterior and inferior for the spatial recognition task than for the pattern recognition task. In the present study we obtained CNVs in five subjects during two tasks identical to the MEG study. The elicited electric potentials were modeled with four spatio-temporal dipoles for each task, three of which accounted for the visual evoked response and one that accounted for the CNV. For all subjects the dipole explaining the CNV was always localized in the frontal region of the head, however, the dipole obtained during the visual spatial recognition task was more anterior than the one obtained during the pattern recognition task. Thus, task-specific CNV sources were again observed, although the stable model consisted of only one dipole located close to the midline instead of one dipole in each hemisphere. This was a major difference in the CNV sources between the previous MEG and the present electric source analysis results. We discuss the possible basis for the difference between the two methods used to study slow brain activity that is believed to originate from extended cortical patches.     

The Marriage Contract

This article is intended to serve as an introduction to the concept of the marriage contract, which has proved to be a useful clinical tool for clarification and treatment of troubled marriages. Transactional as well as intrapsychic factors are important aspects of marital dynamics. The contract concept employs both these behavioral parameters and facilitates therapeutic intervention at both levels.     

Comparison of output order in free recall

Two measures of output order in free recall were examined and shown to vary with characteristics of recall unrelated to output order. The output location of a subset of items in recall, using the standard recall rank measure and the “observed minus expected” score, varied both with number of items in the subset and total number of items recalled. A new measure of output order (the relative index of priority or RIP score) was proposed that is invariant with these characteristics of recall, providing an uncontaminated empirical index of the output location of a subset of items in the recall sequence.