Social representations and intergroup conflicts: Who's smoking here?

We studied the influence of explicitating a social conflict between smokers and nonsmokers on the social representations held about tobacco. Two representations were found: a psychological' representation which was defined by psychological explanations of the causes of beginning to smoke, a characterization of smokers as psychologically disturbed, and negative feelings towards smokers; a second defensive representation which attributes smoking to social factors, and hold both a positive stereotype of smokers and positive feelings towards smokers. The percentage of smokers who adhere to the defensive representation increased significantly when the conflict was made salient. Non-smokers were not influenced by the explicitation of the social conflict. The structure of each representation was analyzed. It was found that in the psychological' representation the structuring element was the negative stereotype of smokers. By contrast, the structuring element in the defensive representation was identification with smokers. The implicatlons of this data for theories of both intergroup relations and social representations are discussed.     

Photoelectric-helicoidal spirometer

This paper describes a photoelectric-helicoidal spirometer that has been designed in our laboratory. It includes a cylindrical helix (or turbine) partitioned in each of its blades by means of opaque plates transversally disposed. These plates obstruct the ray of light emitted by a diode, preventing it from reaching a photoreceptor located at the opposite side of the turbine. These basic elements are located in a module that can be adjusted to a mask that covers nostrils and mouth. Control software for this device is also described. The software facilitates a graphical representation of respiratory activity, as well as its storage in the computer. Software has been designed to be adaptable to any digital-to-analog converter. Both the device and the software have several advantages over traditional spirometers, as well as other nonspirometric techniques for studying respiratory activity.     

Sex-role orientation and stereotypes about male-female sexuality

An experiment was conducted to examine the stereotypes about human sexuality held by persons of different sex-role orientations. Sex-typed and androgynous subjects were given bogus information about the sexual experience of another person. This other person was either a male or a female and either high or low in sexual experience. The subjects were then shown some erotic slides and asked to predict how sexually aroused the target person would be by viewing these stimuli. Additionally, the subjects were asked to rate the target person on traits of a sexual and evaluative nature. The results showed, as predicted, that the sexual experience of a female target influences how much sexual arousal is attributed to her. Female targets of high experience were attributed more arousal than inexperienced female targets. For male targets, no such difference was found. Ratings of the targets on an evaluative dimension revealed a double standard: Sexually experienced females were rated lower than were inexperienced females; no difference was found for male targets. In addition, sex-typed subjects tended to express more traditional stereotypes of sexuality than androgynous subjects. The influence that these stereotypes may have in guiding malefemale interactions is discussed.This article is based on the author's doctoral dissertation, submitted to Kansas State University. The author gratefully acknowledges the assistance of William Giffitt, and his helpful comments and suggestions.     

Diffuse Lewy Body Disease: Clinical,Pathological, and Neuropsychological Review

The pathophysiological etiologies and clinical presentations of neurodegenerative dementias have been found to be complex and heterogeneous. Recently, Lewy body inclusions have been identified as an etiological factor in 20–34% of autopsied dementia cases. The term diffuse Lewy body disease (DLBD) is generally accepted as the diagnostic term representative of this currently under-reported and under-recognized disease. This article reviews the literature on the clinical, pathological, and neuropsychological features of this disorder. Differential diagnostic issues are discussed as well as current pharmacological treatment. Nine confirmed cases of DLBD are presented to demonstrate the various features of this disorder. The diagnostic implications of neuropsychological examination results are discussed in relation to other common dementing neurologic diseases.     

Neuronal NT-3 Is not Required For Synaptic Transmission or Long-Term Potentiation in Area CA1 of the Adult Rat Hippocampus

Neurotrophic factors, including BDNF and NT-3, have been implicated in the regulation of synaptic transmission and plasticity. Previous attempts to analyze synaptic transmission and plasticity in mice lacking the NT-3 gene have been hampered by the early death of the NT-3 homozygous knockout animals. We have bypassed this problem by examining synaptic transmission in mice in which the NT-3 gene is deleted in neurons later in development, by crossing animals expressing the CRE recombinase driven by the synapsin I promoter to animals in which the NT-3 gene is floxed. We conducted blind field potential recordings at the Schaffer collateral–CA1 synapse in hippocampal slices from homozygous knockout and wild-type mice. We examined the following indices of synaptic transmission: (1) input-output relationship; (2) paired-pulse facilitation; (3) post-tetanic potentiation; and (4) long-term potentiation: induced by two different protocols: (a) two trains of 100-Hz stimulation and (b) theta burst stimulation. We found no difference between the knockout and wild-type mice in any of the above measurements. These results suggest that neuronal NT-3 does not play an essential role in normal synaptic transmission and some forms of plasticity in the mouse hippocampus.     

An exploratory study on the development of beliefs about symptoms as signals of arterial hypertension

An exploratory study on the development of beliefs about symptoms as signals of arterial hypertension. In spite of hypertension is known as an asymptomatic health problem, most of the people with such a diagnosis are convinced of experiencing very specific symptoms associated to specific changes in blood pressure (BP). In addition, such beliefs may affect treatment adherence. Previous studies have shown that hypertensive patients use the information they considered right about BP symptoms to regulate the type of decisions they follow in adhering to treatment. The aim of this study is to explore specific variables related with the formation of beliefs about symptoms in a sample of 171 hypertensive patients. Results show that 81,3% of the patients perceived specific symptoms related to changes in hypertension as well as that variables related with the development of these beliefs were mostly: (1) the presence of symptoms during the diagnosis process, (2) the occurrence of hypertensive crisis, and (3) the information provided by others concerning the relationships between symptoms and BP changes. The importance of paying attention to the beliefs of specific symptoms as well as to the circumstances related with the formation process of such beliefs is discussed.     

Subtypes of drug-addicts in treatment: empirical support for a distinction between Type A and Type B

This study examines the possibility of replicating and generalizing a multidimensional typology of drug-addicts by means of the evaluation of 320 participants who were receiving outpatient treatment for their problem of addiction. A two-stage cluster analysis was performed, revealing the existence of two typologies of consumers, called type A and Type B. The participants classified as Type B showed various indicators of chronicity (higher mean age, higher unemployment rate), more severity of their problem of drug consumption and of medical aspects, employment support, legal, family/social and psychiatric problems in comparison with Type A. Participants from the latter group reported active employment as their main source of income and they had consumed drugs for fewer years. However, they presented more severity associated with alcohol consumption. In view of these data, Type A is called functional drug-addict and Type B chronic drug-addict. Once the groups of drug-addicts were delimited, a more specific characterization was made, taking seven problem areas into account: medical, employment support, alcohol, drugs, legal, family/social, and psychiatric areas. As a general conclusion, more psychosocial severity was observed in Type B as compared with Type A. Lastly, the implications and usefulness of grouping drug-addicts into typologies is discussed.     

Alpha2A-adrenoceptor stimulation improves prefrontal cortical regulation of behavior through inhibition of cAMP signaling in aging animals

The working-memory functions of the prefrontal cortex (PFC) are improved by stimulation of postsynaptic, alpha2A-adrenoceptors, especially in aged animals with PFC cognitive deficits. Thus, the alpha2A-adrenoceptor agonist, guanfacine, greatly improves working-memory performance in monkeys and rats following systemic administration or intra-PFC infusion. Alpha2A-adrenoceptors are generally coupled to Gi, which can inhibit adenylyl cyclases and reduce the production of cAMP. However, no study has directly examined whether the working-memory enhancement observed with guanfacine or other alpha2A-adrenoceptor agonists results from cAMP inhibition. The current study confirmed this hypothesis in both rats and monkeys, showing that treatments that increase cAMP-mediated signaling block guanfacine's beneficial effects. In aged rats, guanfacine was infused directly into the prelimbic PFC and was challenged with co-infusions of the cAMP analog, Sp-cAMPS. In aging monkeys, systemically administered guanfacine was challenged with the phosphodiesterase 4 inhibitor, rolipram, using intramuscular doses known to have no effect on their own. In both studies, agents that mimicked the actions of cAMP (rats) or increased endogenous cAMP (monkeys) completely blocked the enhancing effects of guanfacine on working-memory performance. These results are consistent with alpha2A-adrenoceptor stimulation enhancing PFC working-memory function via inhibition of cAMP-mediated signaling.