The cortisol awakening response in caregivers of schizophrenic offspring shows sensitivity to patient status

Abstract

Taking care of offspring during a prolonged period of time is probably one of the most stressful life experiences for parents. The present study compares the cortisol awakening response (CAR) in 38 long-term caregivers (mothers and fathers of schizophrenic relatives) with a control group of 32 non-caregivers. Factors such as general stress, caregiver burden, patient severity, and institutionalization were studied. Although a blunted CAR was observed in caregivers in comparison with controls, this difference was not significant. Among caregivers, the absence of institutionalization for the patient is associated with a lack of CAR in caregivers in comparison with caregivers of institutionally supported patients. General stress, caregiver burden, and patient severity themselves did not favor significant changes in CAR. CAR shows greater sensitivity to institutional support than patient severity and perceived stress. Further research is needed to explain the impact of these factors on health and the psychological factors involved.     

RECRIMINATION IN THE ANALYTIC SITUATION: A HYPOTHESIS ABOUT ITS INFLUENCE ON PSYCHOANALYTICAL GROUPS

This paper deals with certain distortions in communication generated by mutual recrimination that is the result of disturbances in the ideal agencies of both parties. Although the ideal ego, superego and ego ideal participate equally in reproach, it is the latter which is the most decisive. In clinical experience, recrimination may easily colour the analytic dialogue. In such cases, interpretation loses its sense of clarification and another type of dialogue replaces it. There, words are used to take possession of the other, for its autonomy is a threat to the static character of the pathology of mourning. The problem of recrimination has also tainted the development of psychoanalysis, to the point of disrupting the process of discovery itself. This paper deals with repercussions in the psychoanalytic movement and also in the elements that constitute its structure. Finally, different variations and disturbances in the psychoanalytic ideal are considered, as well as the involvement of the psychoanalytic institution in preserving or transforming the ideal. Here the importance of institutions and institutional ideals is emphasised. Finally, we suggest that ideals either encourage or hinder the working through of individual and collective mourning.     

Effects of chronic administration with high doses of testosterone propionate on behavioral and physiological parameters in mice with differing basal aggressiveness

The effects of testosterone propionate, an anabolic‐androgenic steroid, on the behavior displayed during a social encounter by gonadally intact male mice were investigated. Animals were distributed into three groups according to their attack latency in a pre‐screening test (high‐, moderate‐, and low‐ attacking mice) and each group received weekly injections of 60 or 120 mg/kg of testosterone or sesame oil for 10 weeks. Behavioral tests were then carried out. Afterwards, organs were weighed and blood samples collected in order to obtain hormonal data. Treatment had a differential impact on attack in the three groups of animals. Only the high‐attacking testosterone‐treated mice showed lower total duration of attack than their controls. Those that received 60 mg/kg spent more time exhibiting exploratory behaviors. As an index of the anabolic activity of the drug, all testosterone‐treated mice had heavier kidneys and, as an index of the androgenic activity of testosterone propionate, they had heavier seminal vesicles, lighter testes, and showed higher testosterone levels in a dose‐dependent way than their controls. Hence, the effect of treatment on peripheral physiological parameters was similar in all three groups whereas behavioral effects differed depending on basal aggressiveness, considered a characteristic of coping style. Aggr. Behav. 29:173–189, 2003. © 2003 Wiley‐Liss, Inc.     

Electric source localization adds evidence for task-specific CNVs

This study was an attempt to replicate recent magnetoencephalographic (MEG) findings on human task-specific CNV sources (Basile et al., Electroencephalography and Clinical Neurophysiology 90, 1994, 157-165) by means of a spatio-temporal electric source localization method (Scherg and von Cramon, Electroencephalography and Clinical Neurophysiology 62, 1985, 32-44; Scherg and von Cramon, Electroencephalography and Clinical Neurophysiology 65, 1986, 344-360; Scherg and Berg, Brain Electric Source Analysis Handbook, Version 2). The previous MEG results showed CNV sources in the prefrontal cortex of the two hemispheres for two tasks used, namely visual pattern recognition and visual spatial recognition tasks. In the right hemisphere, the sources were more anterior and inferior for the spatial recognition task than for the pattern recognition task. In the present study we obtained CNVs in five subjects during two tasks identical to the MEG study. The elicited electric potentials were modeled with four spatio-temporal dipoles for each task, three of which accounted for the visual evoked response and one that accounted for the CNV. For all subjects the dipole explaining the CNV was always localized in the frontal region of the head, however, the dipole obtained during the visual spatial recognition task was more anterior than the one obtained during the pattern recognition task. Thus, task-specific CNV sources were again observed, although the stable model consisted of only one dipole located close to the midline instead of one dipole in each hemisphere. This was a major difference in the CNV sources between the previous MEG and the present electric source analysis results. We discuss the possible basis for the difference between the two methods used to study slow brain activity that is believed to originate from extended cortical patches.     

Comparison of output order in free recall

Two measures of output order in free recall were examined and shown to vary with characteristics of recall unrelated to output order. The output location of a subset of items in recall, using the standard recall rank measure and the “observed minus expected” score, varied both with number of items in the subset and total number of items recalled. A new measure of output order (the relative index of priority or RIP score) was proposed that is invariant with these characteristics of recall, providing an uncontaminated empirical index of the output location of a subset of items in the recall sequence.     

Reflections on trauma,symbolization and psychic pain in a case of neurosis and a case of psychosis

This paper seeks to advance some considerations on trauma, historical reality, its symbolization and the psychic pain generated by the investigation of unconscious processes in psychoanalytic treatment. These themes will be explored by demonstrating the differences arising between traumatic experiences and their expression in phantasy, as they occurred in a case of neurosis and another of psychosis. In each case, the differences in the features of the symbolization and the processes of working through shall also be taken into consideration. Particular attention shall be paid to the specific difficulties encountered by the analyst in the interpretative treatment of the trauma resulting from the amount of psychic pain induced in the patient, which at times proves to be an insurmountable barrier and a destructive distortion of the process.     

The Role of Parental Depressive Symptoms in Predicting Dysfunctional Discipline Among Parents at High-Risk for Child Maltreatment

Parental depressive symptoms are an important public health concern because they have been linked, in numerous previous studies, to negative parenting behaviors including dysfunctional discipline and child abuse and neglect. Taking this into consideration, parental depressive symptoms warrant particular attention among families with child maltreatment allegations—a group at high risk of dysfunctional discipline and future physical abuse. The current study sought to examine relations between parental depressive symptoms and dysfunctional discipline in an ethnically diverse sample of 234 families who were referred for psychological services due to concerns of child maltreatment. Referrals were made by school, medical, or child welfare personnel. 59.8 % of children were male and the average age was 7.05 years. Results indicated that parental depressive symptoms were significantly correlated with dysfunctional discipline including laxness, over-reactivity, and hostility. However, all three relations lost statistical significance after controlling for parental stress. The findings of this study suggest that well-documented relations between parental depression and negative parenting behavior may be driven by elevated parental stress rather than reflecting risks uniquely associated with depressive pathology.     

Argentines’ collective memories of the military Junta of 1976: differences and similarities across generations and ideology

Although memories about a nation's past usually are semantic in nature, a distinction needs to be made between lived and distant semantic collective memories. The former refers to memories of community-relevant events occurring during the lifetime of the rememberer, whereas the latter to memories of distant events. Does the content of lived and distant semantic collective memories differ? Employing both free and cued recall, we examined the memories of younger and older Argentines of the Military Junta of 1976. We also examined the effects of political ideology. Content analysis indicated that (1) lived semantic collective memories were more likely to contain personal recollections than distant semantic collective memories, even though those with distant semantic collective memories could have incorporated memories of the parent's personal experience in their recollections, (2) lived semantic collective memories contained more causal statements, and (3) those on the Right with distant semantic collective memories were more likely to claim that they “Don't know” or offer positive accounts of the Junta, suggesting a need to “defend” the reputation of those on the Right. The results are discussed in terms of the goals and plans different generations might have when recollecting their nation's past.