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Wistar rats (n = 95) were trained in a pole-jumping apparatus (10 trials/session/day) to investigate the involvement of centrally and peripherally released endogenous AVP in their acquisition rate and to examine the feasibility of the microdialysis technique for the administration of peptides during a behavioral test. After session 1, a microdialysis probe was implanted into the septum; during sessions 2 and 3 the probe was perfused with artificial cerebrospinal fluid (aCSF) alone or containing either AVP (delivered amount via the probe: 0.2 ng) or the V1 (d(CH2)5Tyr(Me)AVP, 5.0 ng) or the V2/V1 (d(CH2)5-D-Tyr(Et)VAVP, 5.0 ng) antagonist. Administration of AVP via microdialysis into the septum failed to alter the acquisition rate of pole jumping. Also, ip application of both hypertonic saline and the AVP V1 antagonist (10 micrograms) in another experiment failed to show a significant effect upon behavior. Septal administration of the V1 or the V2/V1 antagonist via microdialysis, however, produced a significantly impaired performance. The results indicate that AVP release within the septum is involved in the acquisition of pole-jumping behavior probably mediated by the V1 receptor subtype. An additional involvement of the V2 receptor subtype, however, cannot be entirely excluded. The microdialysis technique proved to be a potent tool to administer substances concomitantly with behavioral tests. 相似文献
13.
Was sind “ek-statische Maschinen”? (Gedanken aus und zu: M. K. Mamardašvili,Wissenschaft und Kultur)
Ohne ZusammenfassungM. K. Mamardavili, Nauka i kul'tura, inMetodologieskie problemy istorikonaunych issledovanij, M., Nauka, 1982, str. 38–58. Zitate aus diesem Aufsatz werden im Text mit der in Klammern gesetzten Seitenzahl ausgewiesen. 相似文献
14.
To increase understanding of the relationships between gender and causal attributions, dispositional and situational variables were examined to determine if they affected causal attributions differently if the subjects were females or males. Four dispositional variables—locus of control, neuroticism, achievement motivation, and self-esteem—and five situational variables—expectancy of success, self-reported commitment, perceived productivity, perceived task complexity, and actual performance—were examined for their moderating effects on the gender-causal attributional relationships. The dispositional variables did not moderate any causal relationships. By comparison, four situational variables—performance, commitment, productivity, and complexity—moderated at least one of the gender-attribution relationships. It was concluded that more attention should be directed to the identification of situational moderators. 相似文献
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L D Ludwig 《Journal of personality》1970,38(2):167-176
This study examined the relationship between elation-depression and desire for excitement on both intra- and interindividual levels. It was hypothesized that there would be a positive linear relationship between elation and desire for tranquillity These intraindividual hypotheses received strong support. This support would suggest that radical incongruities between activity demands and mood preparedness are often painful and would imply that in order for mood alteration to be successful it must take place gradually It was also hypothesized that characteristic level of elation-depression would be positively related to mean ratings of desire for excitement, positively related to score on a desire for excitement test, and negatively related to mean ratings of desire for tranquillity These interindividual hypotheses were not supported. Although it is probably most reasonable to accept the lack of correspondence between intra- and interindividual results, the operation of social comparison effects and social desirability bias may have obscured the predicted interindividual relationships 相似文献
17.
Vandra L. Huber Gregory B. Northcraft Margaret A. Neale 《Organizational behavior and human decision processes》1990,45(2)
The purpose of this study was to explore the impact of two factors—decision strategy and the number of openings—on selection decisions. Two hundred graduate and undergraduate students participated in a human resource employment screening simulation. Decision strategy was varied by having candidates evaluate resumes and letters of application for 20 candidates one-at-a-time (sequentially) or all at once (simultaneously). The number of position openings was either one or three. Decision strategy affected the number of candidates accepted, acceptance threshold, and decision time. The number of openings affected selection decisions in the simultaneous but not the sequential context. Implications of these results for selection processes are discussed. 相似文献
18.
Rodger Beehler 《Studies in Philosophy and Education》1990,10(4):315-335
The essay examines the argument advanced by E.D. Hirsch, Jr., for instituting ‘cultural literacy’ as a fundamental priority of schools. A number of confusions and equivocations in Hirsch's reasoning are identified, and the propensity of his project to indoctrinate is exposed. Among the features of Hirsch's argument shown to be troubling are his shifting construal of ‘language’, his inconsistency about the requirements of cultural literacy, and his uncritical relation to traditional images of the American past and present. The upshot is to raise the question why Hirsch's project has elicited wide support and praise. 相似文献
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Jörg R. J. Schirra 《Kognitionswissenschaft》1997,6(4):177-195
How can we explain that an assertion on something perceived can be understood in the same manner by somebody who cannot perceive that scene? This problem bases the interest in computational linguistics in how listener modeling could possibly be harmonized with reference semantics. Mental images substituting real perception appear as a way out. The architecture of the listener model has to be adapted to the creation and use of such pictorial data structures. Furthermore, the relation between the latter and a verbal (i. e., propositional) representation must be understood. The resulting architecture of a listener model with reference semantics can be employed to solve communicational problems from three general classes in a better way, as is demonstrated by an example implementation. 相似文献