Rapid modulation of distributed brain activity by Transcranial Magnetic Stimulation of human motor cortex

This paper reviews the effects of single and repetitive transcranial magnetic stimuli (rTMS) delivered to one cortical area and measured across distributed brain regions using electrophysiological measures (e.g. motor thresholds, motor evoked potentials, paired-pulse stimulation), functional neuroimaging (including EEG, PET and fMRI) and behavioural measures. Discussion is restricted to changes in excitability in the primary motor cortex and behaviour during motor tasks following transcranial magnetic stimulation delivered to primary motor and premotor areas. Trains of rTMS have lasting effects on the excitability of intrinsic and corticofugal neurones, altering the responsiveness of local and remote sites. These effects lead to distributed changes in synaptic activity at rest, and during a range of motor tasks. It is possible to impair or improve performance following rTMS, but for most simple motor tasks performance is unaltered. Changes in distributed activity observed with functional imaging during motor behaviour may represent compensatory activity, enabling maintenance of performance; stimulation of additional cortical areas appears to impair performance. A detailed understanding of the distributed changes in excitability following rTMS may facilitate future attempts to modulate motor behaviour in the healthy brain and for therapeutic purposes.     

Time distortion for expert and novice online game players.

Online game addiction is a new mental disorder. This disorder is difficult to describe because of its comprehensive nature. Many online game players have problems controlling their playing time. They cannot stop playing a game that they enjoy. This research surveyed the past literature on "flow" and time disorder theory. A time distortion experiment was conducted. This research invited 64 children, teenagers, and young adults to investigate player skill and playing time effects on online game break-off. The playing experience and degree of time distortion were measured and analyzed. The results showed that both novice and expert online game players were subject to time distortion. The participants had difficulty breaking off from the game without intrusion by others in the real world. This research also suggests eight questions for self-evaluation for online game addiction.     

Effects of category diversity on learning,memory, and generalization

In this study, we examined the effect of within-category diversity on people's ability to learn perceptual categories, their inclination to generalize categories to novel items, and their ability to distinguish new items from old. After learning to distinguish a control category from an experimental category that was either clustered or diverse, participants performed a test of category generalization or old-new recognition. Diversity made learning more difficult, increased generalization to novel items outside the range of training items, and made it difficult to distinguish such novel items from familiar ones. Regression analyses using the generalized context model suggested that the results could be explained in terms of similarities between old and new items combined with a rescaling of the similarity space that varied according to the diversity of the training items. Participants who learned the diverse category were less sensitive to psychological distance than were the participants who learned a more clustered category.     

Redintegration and lexicality effects in children: Do they depend upon the demands of the memory task?

The effect of long-term knowledge upon performance in short-term memory tasks was examined for children from 5 to 10 years of age. The emergence of a lexicality effect, in which familiar words were recalled more accurately than unfamiliar words, was found to depend upon the nature of the memory task. Lexicality effects were interpreted as reflecting the use of redintegration, or reconstruction processes, in short-term memory. Redintegration increased with age for tasks requiring spoken item recall and decreased with age when position information but not naming was required. In a second experiment, redintegration was found in a recognition task when some of the foils rhymed with the target. Older children were able to profit from a rhyming foil, whereas younger children were confused by it, suggesting that the older children make use of sublexical phonological information in reconstructing the target. It was proposed that redintegrative processes in their mature form support the reconstruction of detailed phonological knowledge of words.     

Similarity as transformation

We propose that similarity is determined by the transformation distance between representations: entities which are perceived to be similar have representations which are readily transformed into one another, whereas transforming between dissimilar entities requires many transformations. We present three experiments that indicate that similarity is strongly influenced by transformation distance. These data present a challenge for featural or spatial accounts of similarity. Finally, we introduce a family of transformation-based accounts of similarity, called 'Representational Distortion', as a specific example of a transformational approach to similarity.     

Using auditory streaming to reduce disruption to serial memory by extraneous auditory warnings

Three experiments were conducted to examine the effects of extraneous speech warnings (i.e., low-priority warnings initiated during high-priority tasks) on cognitive performance and whether organizing the auditory warnings into streams can attenuate any disruption. Experiment 1 demonstrated that a variety of speech warnings can be separated into perceptually distinct streams by allocating them to discrete spatial locations. Experiment 2 showed that increasing the rate of presentation of the warnings to promote streaming decreased clarity ratings but increased perceived urgency ratings. Experiment 3 demonstrated that the disruption to serial memory for navigational information by extraneous speech warnings could be attenuated by streaming. Results are interpreted in light of previous research, and practical implications for auditory warning design are discussed.     

Test of parenting skills

An item pool was developed to assess basic parenting skills in the areas of attachment, emotional capacity, judgment, knowledge of child development, and safety. Initially, 200 items were generated and completed by a sample of 15 parents. Item scores correlated with scores on a social desirability scale or having low variance were edited or eliminated. A sample of 56 parents completed the revised scale, a social desirability scale, and the Adult-Adolescent Parenting Inventory. The reliabilities of the final subscales of the Test of Parenting Skills were modest, ranging from .56 to .77. Scores on the subscales were also correlated with those subscales from the Adult-Adolescent Parenting Inventory. With the exception of the Judgment scores being correlated with the use of harsh discipline, the significant correlations suggested concurrent validity. The individual subscales require additional refinement to achieve adequate internal consistency, but they have potential for measuring competency in core parenting skills.     

Guilt, shame, and symptoms in children

The authors asked whether evidence could be found for adaptive or maladaptive aspects of guilt and shame in 5-12-year-old children (44 boys, 42 girls). Children completed semiprojective and scenario-based measures thought to assess shame, guilt, or both. Their parents (N = 83) completed the Child Behavior Checklist to assess child symptoms. Shame and projective guilt were related to symptoms; they also were associated with self-blame and attempts to minimize painful feelings. Scenario-based guilt was related to fewer symptoms in boys but to greater symptoms in girls. This measure of guilt reflected concerns with adhering to standards, expressing empathy, and taking appropriate responsibility. Discussion focuses on possible origins of differential symptom-emotion links in boys and girls as well as measurement implications.     

Pattern of Neuropsychological Deficit at Age Five Years Following Neonatal Unilateral Brain Injury

The pattern of language deficit following left-hemisphere brain injury and visual/spatial deficit following right-hemisphere injury in an adult or older child is well recognized, but has been inconsistently reported following presumed neonatal brain injury. Our prospective study of 24 children at age 5 with documented neonatal unilateral brain injury lends support to the theory of hemisphere specialization at the time of birth. Twelve children who had unilateral left-hemisphere lesion were compared to 12 children with unilateral right-hemisphere lesion of similar timing and severity. Relative visual/spatial deficit following right-hemisphere lesion and receptive language deficit following left-hemisphere lesion were identified. Lateralized measures of grip strength, fine motor speed, and fine motor dexterity were not significantly different between the groups for either hand in this nonhemiparetic study sample. Only one child with a left-hemisphere lesion was left-handed, and only one child (right-lesion) had a hemiparesis.