Evidence for a sensitive period in the effects of early life stress on hippocampal volume

Exposure to stress has been causally linked to changes in hippocampal volume (HV). Given that the hippocampus undergoes rapid changes in the first years of life, stressful experiences during this period may be particularly important in understanding individual differences in the development of the hippocampus. One hundred seventy‐eight early adolescents (ages 9–13 years; 43% male) were interviewed regarding exposure to and age of onset of experiences of stress; the severity of each stressful event was rated by an objective panel. All participants underwent structural magnetic resonance imaging, from which HVs were automatically segmented. Without considering the age of onset for stressful experiences, there was a small but statistically significant negative association of stress severity with bilateral HV. When considering the age of onset, there was a moderate and significant negative association between stress severity during early childhood (through 5 years of age) and HV; there was no association between stress severity during later childhood (age 6 years and older) and HV. We provide evidence of a sensitive period through 5 years of age for the effects of life stress on HV in adolescence. It will be important in future research to elucidate how reduced HV stemming from early life stress may contribute to stress‐related health outcomes.     

Brain bases of morphological processing in Chinese‐English bilingual children

Can bilingual exposure impact children's neural circuitry for learning to read? To answer this question, we investigated the brain bases of morphological awareness, one of the key spoken language abilities for learning to read in English and Chinese. Bilingual Chinese‐English and monolingual English children (N = 22, ages 7–12) completed morphological tasks that best characterize each of their languages: compound morphology in Chinese (e.g. basket + ball = basketball) and derivational morphology in English (e.g. re + do = redo). In contrast to monolinguals, bilinguals showed greater activation in the left middle temporal region, suggesting that bilingual exposure to Chinese impacts the functionality of brain regions supporting semantic abilities. Similar to monolinguals, bilinguals showed greater activation in the left inferior frontal region [BA 45] in English than Chinese, suggesting that young bilinguals form language‐specific neural representations. The findings offer new insights to inform bilingual and cross‐linguistic models of language and literacy acquisition.     

Does Group CBT for Depression Do What It Says on the Tin? A Systemic Review and Meta-analysis of Group CBT for Depressed Adults (2000–2016)

The present study aimed to update previous meta-analyses of gCBT, and focus specifically on recent studies in which the Beck Depression Inventory (BDI) was used to assess outcome. PsycINFO, PubMed, EMBASE, and Cochrane were searched for eligible studies. Both randomized controlled trials (RTC, k = 9) and non-RTCs (k = 1) published since 2000 were included. On the BDI large significant effect sizes were found for gCBT compared with treatment as usual (TAU, d = 4.64), wailing list controls (WLC, d = 1.20), and both of these comparison conditions combined with studies of well-defined alternative treatments (ALT, d = 1.61). On the BDI a moderate effect size (d = 0.53) was found for comparisons of gCBT and ALT groups. gCBT also had large and significant effects on depressive cognition assessed with the Automatic Thoughts Questionnaire and the Dysfunctional Attitudes Scale compared with WLC and ALT comparison groups (d = 2.66). This meta-analysis shows that gCBT is a robust intervention for depression in adults.     

Changing Kinematics as a Means of Reducing Vulnerability to Physical Attack1

Three experiments investigated whether women can change their walking style and hence reduce their vulnerability to physical attack. In Experiment 1, women were videotaped walking normally and when imagining themselves in a situation of low personal safety. Women were rated as harder to attack in the low safety condition. Differences in walking style accounted for differences in ease‐of‐attack ratings. Experiment 2 compared walking styles and vulnerability of women before and after completing a self‐defense course. No differences were seen across sessions. Experiment 3 investigated walking styles and vulnerability of women before and after completing individualized walking training programs. Differences in vulnerability between sessions were revealed and could be accounted for by changes in walking‐style features.     

A feasibility study of Acceptance and Commitment Therapy for emotional dysfunction following psychosis

The experience of psychosis can lead to depression, anxiety and fear. Acceptance and Commitment Therapy (ACT) facilitates individuals to accept difficult mental experiences and behave in ways that are consistent with personally held values. This study was a single (rater) blind pilot randomised controlled trial of ACT for emotional dysfunction following psychosis. Twenty-seven participants with psychosis were randomised to either: ten sessions of ACT plus treatment as usual (TAU) or TAU alone. The Hospital Anxiety and Depression Scale, Positive and Negative Syndrome Scale, Acceptance and Action Questionnaire, Kentucky Inventory of Mindfulness Skills and Working Alliance Inventory were used. Individuals were assessed at baseline and 3 months post-baseline. The individuals randomised to receive ACT found the intervention acceptable. A significantly greater proportion of the ACT group changed from being depressed at time of entry into the study to not being depressed at follow-up. The ACT group showed a significantly greater increase in mindfulness skills and reduction in negative symptoms. Results indicated that individuals randomised to ACT had significantly fewer crisis contacts over the study. Changes in mindfulness skills correlated positively with changes in depression. ACT appears to offer promise in reducing negative symptoms, depression and crisis contacts in psychosis.     

The influence of heightened body‐awareness on walking through apertures

The reported study measured the ratio between aperture‐width and hip‐width that marked the critical transition from frontal walking to body rotation for male and female participants. Half of the participants of each sex wore form‐fitting lycra clothes and half loose‐fitting jogging suits. Participants wearing the form‐fitting clothing reported heightened body awareness relative to those wearing the loose‐fitting clothing. For male participants this difference was reflected in a smaller aperture‐to‐hip ratio in the form‐fitting than loose‐fitting clothing condition. That is, males walked frontally through smaller apertures when wearing form‐fitting than when wearing loose‐fitting clothing. For females there was no difference in walking action as a function of clothing style. Results are discussed in terms of the perception of action opportunities in the environment, the influence of body awareness on such perception and sex differences. Copyright © 2009 John Wiley & Sons, Ltd.     

Acquired flavour preferences: contextual control of adaptation-level effects

This experiment investigated the role of context in the expression of conditioned flavour preferences. Rats were trained on a mixture of almond and sucrose and were then given intermixed exposures to almond in one context (Context A) and to sucrose in a second context (Context S). Finally, choice tests were given in both contexts, with one group given almond-versus-water tests and the other almond + sucrose-versus-sucrose tests. Preference for almond over water was greater in Context A than in Context S. Conversely, preference for almond + sucrose over sucrose was greater in Context S than in Context A. These results suggest that the perceived sweetness of a flavour depends on the context in which it is presented and confirm that expression of a flavour preference depends on the type of test employed.     

Go or no‐go? Developmental improvements in the efficiency of response inhibition in mid‐childhood

This experiment used a modified go/no‐go paradigm to investigate the processes by which response inhibition becomes more efficient during mid‐childhood. The novel task, which measured trials on which a response was initiated but not completed, was sensitive to developmental changes in response inhibition. The effect of inducing time pressure by narrowing allowable response time was also examined. While increasing time pressure did not reduce the inhibitory demands of the task for either age group, older children (aged 9 to 11 years) were able to inhibit their responses at an earlier stage of movement than younger children (aged 5 to 7 years). This shows that as children get older they become more efficient at controlling their behaviour which drives developmental improvements in response inhibition.     

Treatment of Missing Data: Beyond Ends and Means

The ethical decision making process behind the treatment of missing data has yet to be examined in the research literature in any discipline. The purpose of the current paper is to begin to discuss this decision-making process in view of a Foucauldian framework. The paper suggests how the ethical treatment of missing data should be considered from the adoption of this theoretical framework.