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Cerebral blood flow in 5‐ to 8‐month‐olds: Regional tissue maturity is associated with infant affect
M. Catalina Camacho Lucy S. King Amar Ojha Cheyenne M. Garcia Lucinda M. Sisk Anna C. Cichocki Kathryn L. Humphreys Ian H. Gotlib 《Developmental science》2020,23(5)
Infancy is marked by rapid neural and emotional development. The relation between brain function and emotion in infancy, however, is not well understood. Methods for measuring brain function predominantly rely on the BOLD signal; however, interpretation of the BOLD signal in infancy is challenging because the neuronal‐hemodynamic relation is immature. Regional cerebral blood flow (rCBF) provides a context for the infant BOLD signal and can yield insight into the developmental maturity of brain regions that may support affective behaviors. This study aims to elucidate the relations among rCBF, age, and emotion in infancy. One hundred and seven mothers reported their infants' (infant age M ± SD = 6.14 ± 0.51 months) temperament. A subsample of infants completed MRI scans, 38 of whom produced usable perfusion MRI during natural sleep to quantify rCBF. Mother‐infant dyads completed the repeated Still‐Face Paradigm, from which infant affect reactivity and recovery to stress were quantified. We tested associations of infant age at scan, temperament factor scores, and observed affect reactivity and recovery with voxel‐wise rCBF. Infant age was positively associated with CBF in nearly all voxels, with peaks located in sensory cortices and the ventral prefrontal cortex, supporting the formulation that rCBF is an indicator of tissue maturity. Temperamental Negative Affect and recovery of positive affect following a stressor were positively associated with rCBF in several cortical and subcortical limbic regions, including the orbitofrontal cortex and inferior frontal gyrus. This finding yields insight into the nature of affective neurodevelopment during infancy. Specifically, infants with relatively increased prefrontal cortex maturity may evidence a disposition toward greater negative affect and negative reactivity in their daily lives yet show better recovery of positive affect following a social stressor. 相似文献
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After a pretreatment screening analysis suggested that rumination by a 19‐year‐old man with autism was maintained by automatic reinforcement, we evaluated his preference for three snack foods and the frequency of his rumination after consuming each. Rumination was more common after eating high‐preference foods. We then examined noncontingent access to a type of lollipop (i.e., a Ring Pop?) to decrease rumination. The Ring Pop? reduced rumination to moderately low levels. Next, to further decrease rumination, we added a reprimand, which reduced rumination to near zero levels. Finally, we evaluated the reprimand by itself, which resulted in a reduction in rumination roughly equivalent to that produced by the Ring Pop?. Results are discussed in terms of the source of reinforcement for rumination and the behavioral mechanisms responsible for intervention effects. 相似文献
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Lucinda Ballantyne 《Psychoanalytic Dialogues》2018,28(1):86-93
Both Deborah Dowd and Sarah Mendelsohn capture the fraught experience of staying near a patient’s dread. I discuss dread as an engagement with unrepresented trauma. With each case I interpret a critical clinical moment as an instance of Winnicott’s object usage, by which the patient leaves omnipotence and finds externality. I introduce a crucial meaning of object usage that I find only implicit in Winnicott’s text: Not only must the analyst survive the patient’s destructiveness, but the analyst also must be disrupted by the patient’s unrepresented trauma. Their patients’ experience of this disruption positions each of these analysts as an other who can be used. 相似文献
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David A. Wilder Anthony T. Fischetti Kristin Myers Yanerys Leon‐Enriquez Lina Majdalany 《Behavioral Interventions》2013,28(3):241-250
We evaluated the effect of response effort on compliance with three children who exhibited noncompliance when asked to relinquish a preferred toy. Participants were given access to a preferred toy and then asked to place the toy in a toy bin, which was located either 0.3 m (low effort) or 3 m (high effort) away. We used a reversal design to evaluate the effect of the effort manipulation. Compliance by all three participants was sensitive to the effort manipulation. In addition, compliance by two participants maintained as the distance required to comply with instructions was systematically increased. Copyright © 2013 John Wiley & Sons, Ltd. 相似文献
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Alexa Smith-Osborne Ann Wilder Elizabeth Reep 《Journal of aggression, maltreatment & trauma》2013,22(5):461-481
In this study, 10 recent meta-analytic and systematic review studies were synthesized on the neurological underpinnings of stress and trauma with implications for the impact of parental post-traumatic stress disorder (PTSD) and resilience among military children. Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) group guidelines and utilizing a validated quality assessment tool, this systematic review of reviews incorporated results from more than 35,971 individuals with stress exposures, effects, or disorders and healthy controls. This synthesis found support for important gene, physiology, and environment correlations and interactions that predict increased risk for stressful life events and PTSD, but not direct transmission, among military children. Future research is needed to determine if these constitute indirect pathways of intergenerational transmission in military children. 相似文献
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Lucinda A. Rasmussen Margaret J. Hughes Colleen A. Murray 《Journal of aggression, maltreatment & trauma》2013,22(3):296-317
ABSTRACT This pilot study examined the use of motivational interviewing (MI) with 20 women receiving services at a domestic violence shelter. The experimental group (n = 10) received regular treatment services (RTS) from shelter counselors who were trained in MI; the control group (n = 10) received RTS only. Fisher's exact test showed that participants who received MI-enhanced RTS were significantly more motivated for change (p = .029), as measured through a dichotomous readiness for change motivational variable on the University of Rhode Island Change Assessment (URICA; Center on Alcoholism, Substance Abuse, &; Addiction Research Division, 1996). Findings suggest that MI can be helpful in increasing the readiness for change in domestic violence survivors who contemplate leaving abusive relationships. 相似文献