Unemployment alters the set point for life satisfaction

Abstract— According to set-point theories of subjective well-being, people react to events but then return to baseline levels of happiness and satisfaction over time. We tested this idea by examining reaction and adaptation to unemployment in a 15-year longitudinal study of more than 24,000 individuals living in Germany. In accordance with set-point theories, individuals reacted strongly to unemployment and then shifted back toward their baseline levels of life satisfaction. However, on average, individuals did not completely return to their former levels of satisfaction, even after they became reemployed. Furthermore, contrary to expectations from adaptation theories, people who had experienced unemployment in the past did not react any less negatively to a new bout of unemployment than did people who had not been previously unemployed. These results suggest that although life satisfaction is moderately stable over time, life events can have a strong influence on long-term levels of subjective well-being.     

ERK1/2 activation is necessary for BDNF to increase dendritic spine density in hippocampal CA1 pyramidal neurons

Brain-derived neurotrophic factor (BDNF) is a potent modulator of synaptic transmission and plasticity in the CNS, acting both pre- and postsynaptically. We demonstrated recently that BDNF/TrkB signaling increases dendritic spine density in hippocampal CA1 pyramidal neurons. Here, we tested whether activation of the prominent ERK (MAPK) signaling pathway was responsible for BDNF's effects on spine growth. Slice cultures were transfected with enhanced yellow fluorescent protein (eYFP) by particle-mediated gene transfer, and CA1 pyramidal neurons were imaged by laser-scanning confocal microscopy. We confirmed that BDNF (24 h) increases spine density in apical dendrites of CA1 neurons. The MEK (ERK kinase) inhibitors PD98059 and U0126 completely prevented the increase in spine density induced by BDNF, without having an effect on spine density by themselves. In contrast to its actions on cortical pyramidal neurons, BDNF had minor and rather localized effects on dendritic complexity in hippocampal pyramidal neurons, increasing the total length, but not the branching of apical dendrites within CA1 stratum radiatum, without affecting basal dendrites in stratum oriens. Our results support the hypothesis that the ERK-signaling pathway not only mediates long-term synaptic plasticity and hippocampal-dependent learning, but it is also involved in the structural remodeling of excitatory spine synapses triggered by neurotrophins.     

Extraversion and emotional reactivity

Six mood induction studies and a meta-analysis were conducted to test 2 models of the extraversion-pleasant affect relation. The affect-level model suggests that extraverts should be happier than introverts in both neutral and positive mood conditions. The reactivity model posits that extraverts react particularly strongly to pleasant stimuli and that they should be happier than introverts only in positive conditions. In all studies, extraverts failed to exhibit greater emotional reactivity when pleasantness items were analyzed. When activated positive affect items were analyzed, results were mixed. The meta-analysis confirmed that there is only a slight reactivity effect overall, and this effect emerges only in activated positive affect items. Furthermore, the meta-analysis showed that the correlation in neutral conditions is strong enough to support the affect-level model.     

Factors influencing the relation between extraversion and pleasant affect

Factors that influence the relation between extraversion and pleasant affect were examined in 6 studies. In Studies 1 through 5, the authors used structural equation modeling techniques to test whether different extraversion and pleasant affect scales and the use of multiple methods of assessment influenced the strength of the relation. In Study 6, the authors conducted a meta-analysis of previous literature to calculate an average effect size and to assess the influence of moderator variables. Results from both the structural equation models and the meta-analysis showed that with only a few exceptions, the use of different extraversion and affect scales resulted in moderate to strong correlations. The use of "on-line" methods of mood assessment (moment reports or daily-diary reports) resulted in lower and more homogeneous correlations than did the use of global, retrospective measures of mood.     

External Validity of Conduct and Oppositional Defiant Disorders Determined by the NIMH Diagnostic Interview Schedule for Children

We administered the Diagnostic Interview Schedule for Children (DISC) two times to a group of youth (222 boys, 147 girls) entering residential care, once at their time of entry and once 1 year later. We then compared their DISC outcomes on Conduct Disorder (CD) and Oppositional Defiant Disorder (ODD) against changes in independent direct observations of diagnostically relevant behavior obtained over the course of that year. Results from hierarchical linear modeling analyses showed significant discriminative relationships between results from the DISC and the independent observations. Specifically, observations of symptomatic behaviors (CD or ODD) decreased for youth who met diagnostic criteria at the first administration of the DISC but not at the second, increased for youth who did not meet criteria at the first administration but did at the second, and did not change for youth who met criteria at both administrations. These results extend the data on the validity of the DISC and support continued research efforts to determine its clinical utility.     

Stress and Coping as Determinants of Adolescent Smoking Behavior1

Relationships between perceived stress, coping, and smoking behavior were examined both cross-sectionally and prospectively in a large sample of English adolescents recruited from secondary schools in East Sussex. Significant cross-sectional and prospective associations are reported between smoking behavior and perceived stress, “cathartic” coping, and perception of smoking as a coping resource. The hypothesis that female adolescents smoke more than do males because they perceive more stress in their lives and cope with it differently was not supported.     

Informant-Based Determinants of Symptom Attenuation in Structured Child Psychiatric Interviews

Informant-related determinants of item attenuation, that is, the drop-off in symptom endorsement rates at retest, were examined in an enriched community subsample of 245 parent–child pairs drawn from the National Institute of Mental Health Methods for Epidemiology of Child and Adolescent Mental Disorders Study. Youngsters and their parents were interviewed with the Diagnostic Interview Schedule for Children (Version 2.3; DISC-2.3) on two occasions with a mean test–retest interval of 12 days. Item attenuation rates were high for both informants, with adults failing to confirm 42% and children 58% of baseline responses at retest. Stepwise regressions revealed that item attenuation at DISC-P retest was higher for adult informants who were younger, and who reported on older and less impaired children. On the DISC-C, attenuation was higher for children who were less impaired, rated as doing worse in school, and who had a longer test–retest interval. These results are broadly consistent with past studies examining the determinants of attenuation and test–retest reliability and have implications for the design and use of structured diagnostic instruments.     

Levels of representation in the interpretation of anaphoric reference and instrument inference

The level of representation accessed when inferences are made during sentence comprehension was examined. The inferences investigated included antecedent assignment for both definite noun phrase anaphors and pronouns and also instrument inferences. In making these inferences, a listener must access the inferred element, whether an antecedent or an instrument, in either a linguistic form representation or a discourse model. The level of representation involved in these inferences was determined by exploiting differences in the lexical-decision and naming tasks, which were argued to exhibit differential sensitivity to representational levels. In three experiments, the priming of antecedent and instrument targets in the lexical decision task was compared with priming of the same targets in the naming task. Differences in the patterns of activation across the two tasks indicated that all three types of inferences required-accessing-elements in a discourse model. Three control experiments ruled out simple context or congruity checking as an explanation for our results. The following conclusions were also supported by these studies: (1) Antecedent assignment occurs immediately after processing an anaphor; (2) antecedent assignment involves inhibition for the inappropriate antecedent rather than facilitation for the appropriate antecedent; (3) although subjects do not make instrument inferences-when they hear isolated sentences containing verbs that strongly imply certain instruments, the inferences are made when sentences are preceded by a context that mentions the instrument.