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11.
From acquisition to consolidation: on the role of brain-derived neurotrophic factor signaling in hippocampal-dependent learning 下载免费PDF全文
Tyler WJ Alonso M Bramham CR Pozzo-Miller LD 《Learning & memory (Cold Spring Harbor, N.Y.)》2002,9(5):224-237
One of the most rigorously investigated problems in modern neuroscience is to decipher the mechanisms by which experience-induced changes in the central nervous system are translated into behavioral acquisition, consolidation, retention, and subsequent recall of information. Brain-derived neurotrophic factor (BDNF) has recently emerged as one of the most potent molecular mediators of not only central synaptic plasticity, but also behavioral interactions between an organism and its environment. Recent experimental evidence indicates that BDNF modulates synaptic transmission and plasticity by acting across different spatial and temporal domains. BDNF signaling evokes both short- and long-term periods of enhanced synaptic physiology in both pre- and postsynaptic compartments of central synapses. Specifically, BDNF/TrkB signaling converges on the MAP kinase pathway to enhance excitatory synaptic transmission in vivo, as well as hippocampal-dependent learning in behaving animals. Emerging concepts of the intracellular signaling cascades involved in synaptic plasticity induced through environmental interactions resulting in behavioral learning further support the contention that BDNF/TrkB signaling plays a fundamental role in mediating enduring changes in central synaptic structure and function. Here we review recent literature showing the involvement of BDNF/TrkB signaling in hippocampal-dependent learning paradigms, as well as in the types of cellular plasticity proposed to underlie learning and memory. 相似文献
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Cross-cultural evidence for the fundamental features of extraversion 总被引:14,自引:0,他引:14
Lucas RE Diener E Grob A Suh EM Shao L 《Journal of personality and social psychology》2000,79(3):452-468
Psychologists have not determined the defining characteristics of extraversion. In four studies, the authors tested the hypothesis that extraversion facets are linked by reward sensitivity. According to this hypothesis, only facets that reflect reward sensitivity should load on a higher order extraversion factor. This model was tested against a model in which sociability links the facets. The authors also tested the generalizability of the model in a diverse sample of participants from 39 nations, and they tested the model using widely used extraversion scales. Results of all studies indicate that only facets that reflect reward sensitivity load on a higher order extraversion factor and that this factor correlates strongly with pleasant affect. Although sociability is undoubtedly an important part of extraversion, these results suggest that extraverts' sociability may be a by-product of reward sensitivity, rather than the core feature of the trait. 相似文献
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Nahinsky ID Lucas BA Edgell SE Overfelt J Loeb R 《The American journal of psychology》2004,117(3):317-340
We investigated the effect of learning one category structure on the learning of a related category structure. Photograph-name combinations, called identifiers, were associated with values of four demographic attributes. Two problems were related by analogous demographic attributes, common identifiers, or both to examine the impact of common identifier, related general characteristics, and the interaction of the two variables in mediating learning transfer from one category structure to another. Problems sharing the same identifier information prompted greater positive transfer than those not sharing the same identifier information. In contrast, analogous defining characteristics in the two problems did not facilitate transfer. We computed correlations between responses to first-problem stimuli and responses to analogous second-problem stimuli for each participant. The analogous characteristics produced a tendency to respond in the same way to corresponding stimuli in the two problems. The results support an alignment between category structures related by analogous defining characteristics, which is facilitated by specific identifier information shared by two category structures. 相似文献
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Why do people express moral outrage? While this sentiment often stems from a perceived violation of some moral principle, we test the counter-intuitive possibility that moral outrage at third-party transgressions is sometimes a means of reducing guilt over one’s own moral failings and restoring a moral identity. We tested this guilt-driven account of outrage in five studies examining outrage at corporate labor exploitation and environmental destruction. Study 1 showed that personal guilt uniquely predicted moral outrage at corporate harm-doing and support for retributive punishment. Ingroup (vs. outgroup) wrongdoing elicited outrage at corporations through increased guilt, while the opportunity to express outrage reduced guilt (Study 2) and restored perceived personal morality (Study 3). Study 4 tested whether effects were due merely to downward social comparison and Study 5 showed that guilt-driven outrage was attenuated by an affirmation of moral identity in an unrelated context. 相似文献
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Righteous or self‐righteous anger? Justice sensitivity moderates defensive outrage at a third‐party harm‐doer 下载免费PDF全文
While bystanders' outrage over moral transgressions may represent a genuine desire to restore justice, such expressions can also be self‐serving—alleviating guilt and bolstering one's moral status. Four studies examined whether individual differences in observer justice sensitivity (JSO) moderate the degree to which outrage at third‐party harm‐doing reflects concerns about one's own moral identity rather than justice per se. Among participants low (vs. high) in JSO, feelings of guilt predicted greater outrage and desire to punish a corporation's sweatshop labor practices (Studies 1 & 2). Furthermore, affirming one's personal moral identity reduced outrage and support for punishing a corporate harm‐doer among those low, but not high in JSO (Studies 3 & 4). Similar moderation was absent for other forms of justice sensitivity and just world beliefs. Effects were not explained by negative affect, empathy, personal harm, or political orientation. Results suggest that JSO uniquely differentiates defensive and justice‐driven moral outrage (150/150). 相似文献
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Prior research has found that perceived discrimination is associated with adverse mental health outcomes among Latinos. However, the process by which this relationship occurs remains an understudied area. The present study investigated the role of acculturative stress in underlying the relationship between perceived discrimination and Latino psychological distress. Also examined was the ability of acculturation to serve as a moderator between perceived discrimination and acculturative stress. Among a sample of Latino adults (N = 669), moderated mediational analyses revealed that acculturative stress mediated the perceived discrimination-psychological distress relationship, and that the link between perceived discrimination and acculturative stress was moderated by Anglo behavioral orientation but not Latino behavioral orientation. The findings are discussed within a stress and coping perspective that identifies the psychological consequences associated with perceived discrimination and acculturative stress. 相似文献
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Familiarity is sometimes associated with midfrontal old/new (FN400) signals, but investigators assume too much by inferring familiarity whenever they identify these signals. We describe how Rosburg and colleagues (2011) made this assumption, yielding potentially faulty conclusions about the recognition heuristic. We provide an alternative interpretation emphasizing implicit processing that can underlie decision-making. 相似文献