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排序方式: 共有318条查询结果,搜索用时 15 毫秒
201.
Augusto Buchweitz Lucas Araújo de Azeredo Breno Sanvicente-Vieira Valentina Metsavaht Car Nathlia Bianchini Esper Ricardo Bernardi Soder Jaderson Costa da Costa Mirna Wetters Portuguez Alexandre Rosa Franco Rodrigo Grassi‐Oliveira 《Developmental science》2019,22(5)
The present study investigated exposure to violence and its association with brain function and hair cortisol concentrations in Latin‐American preadolescents. Self‐reported victimization scores (JVQ‐R2), brain imaging (fMRI) indices for a social cognition task (the ‘eyes test’), and hair cortisol concentrations were investigated, for the first time, in this population. The eyes test is based on two conditions: attributing mental state or sex to pictures of pairs of eyes (Baron‐Cohen, Wheelwright, Hill, Raste, & Plumb, 2001). The results showed an association among higher victimization scores and (a) less activation of posterior temporoparietal right‐hemisphere areas, in the mental state condition only (including right temporal sulcus and fusiform gyrus); (b) higher functional connectivity indices for the Amygdala and Right Fusiform Gyrus (RFFG) pair of brain regions, also in the mental state condition only; (c) higher hair cortisol concentrations. The results suggest more exposure to violence is associated with significant differences in brain function and connectivity. A putative mechanism of less activation in posterior right‐hemisphere regions and of synchronized Amygdala: RFFG time series was identified in the mental state condition only. The results also suggest measurable effects of exposure to violence in hair cortisol concentrations, which contribute to the reliability of self‐reported scores by young adolescents. The findings are discussed in light of the effects of exposure to violence on brain function and on social‐cognitive development in the adolescent brain. A video abstract of this article can be viewed at https://www.youtube.com/watch?v=qHcXq7Y9PBk 相似文献
202.
203.
Lucas RE 《Psychological science》2005,16(12):945-950
Cross-sectional studies show that divorced people report lower levels of life satisfaction than do married people. However, such studies cannot determine whether satisfaction actually changes following divorce. In the current study, data from an 18-year panel study of more than 30,000 Germans were used to examine reaction and adaptation to divorce. Results show that satisfaction drops as one approaches divorce and then gradually rebounds over time. However, the return to baseline is not complete. In addition, prospective analyses show that people who will divorce are less happy than those who stay married, even before either group gets married. Thus, the association between divorce and life satisfaction is due to both preexisting differences and lasting changes following the event. 相似文献
204.
Unemployment alters the set point for life satisfaction 总被引:17,自引:0,他引:17
Abstract— According to set-point theories of subjective well-being, people react to events but then return to baseline levels of happiness and satisfaction over time. We tested this idea by examining reaction and adaptation to unemployment in a 15-year longitudinal study of more than 24,000 individuals living in Germany. In accordance with set-point theories, individuals reacted strongly to unemployment and then shifted back toward their baseline levels of life satisfaction. However, on average, individuals did not completely return to their former levels of satisfaction, even after they became reemployed. Furthermore, contrary to expectations from adaptation theories, people who had experienced unemployment in the past did not react any less negatively to a new bout of unemployment than did people who had not been previously unemployed. These results suggest that although life satisfaction is moderately stable over time, life events can have a strong influence on long-term levels of subjective well-being. 相似文献
205.
ERK1/2 activation is necessary for BDNF to increase dendritic spine density in hippocampal CA1 pyramidal neurons 总被引:5,自引:0,他引:5 下载免费PDF全文
Brain-derived neurotrophic factor (BDNF) is a potent modulator of synaptic transmission and plasticity in the CNS, acting both pre- and postsynaptically. We demonstrated recently that BDNF/TrkB signaling increases dendritic spine density in hippocampal CA1 pyramidal neurons. Here, we tested whether activation of the prominent ERK (MAPK) signaling pathway was responsible for BDNF's effects on spine growth. Slice cultures were transfected with enhanced yellow fluorescent protein (eYFP) by particle-mediated gene transfer, and CA1 pyramidal neurons were imaged by laser-scanning confocal microscopy. We confirmed that BDNF (24 h) increases spine density in apical dendrites of CA1 neurons. The MEK (ERK kinase) inhibitors PD98059 and U0126 completely prevented the increase in spine density induced by BDNF, without having an effect on spine density by themselves. In contrast to its actions on cortical pyramidal neurons, BDNF had minor and rather localized effects on dendritic complexity in hippocampal pyramidal neurons, increasing the total length, but not the branching of apical dendrites within CA1 stratum radiatum, without affecting basal dendrites in stratum oriens. Our results support the hypothesis that the ERK-signaling pathway not only mediates long-term synaptic plasticity and hippocampal-dependent learning, but it is also involved in the structural remodeling of excitatory spine synapses triggered by neurotrophins. 相似文献
206.
Extraversion and emotional reactivity 总被引:1,自引:0,他引:1
Six mood induction studies and a meta-analysis were conducted to test 2 models of the extraversion-pleasant affect relation. The affect-level model suggests that extraverts should be happier than introverts in both neutral and positive mood conditions. The reactivity model posits that extraverts react particularly strongly to pleasant stimuli and that they should be happier than introverts only in positive conditions. In all studies, extraverts failed to exhibit greater emotional reactivity when pleasantness items were analyzed. When activated positive affect items were analyzed, results were mixed. The meta-analysis confirmed that there is only a slight reactivity effect overall, and this effect emerges only in activated positive affect items. Furthermore, the meta-analysis showed that the correlation in neutral conditions is strong enough to support the affect-level model. 相似文献
207.
208.
Factors that influence the relation between extraversion and pleasant affect were examined in 6 studies. In Studies 1 through 5, the authors used structural equation modeling techniques to test whether different extraversion and pleasant affect scales and the use of multiple methods of assessment influenced the strength of the relation. In Study 6, the authors conducted a meta-analysis of previous literature to calculate an average effect size and to assess the influence of moderator variables. Results from both the structural equation models and the meta-analysis showed that with only a few exceptions, the use of different extraversion and affect scales resulted in moderate to strong correlations. The use of "on-line" methods of mood assessment (moment reports or daily-diary reports) resulted in lower and more homogeneous correlations than did the use of global, retrospective measures of mood. 相似文献
209.
Friman PC Handwerk ML Smith GL Larzelere RE Lucas CP Shaffer DM 《Journal of abnormal child psychology》2000,28(3):277-286
We administered the Diagnostic Interview Schedule for Children (DISC) two times to a group of youth (222 boys, 147 girls) entering residential care, once at their time of entry and once 1 year later. We then compared their DISC outcomes on Conduct Disorder (CD) and Oppositional Defiant Disorder (ODD) against changes in independent direct observations of diagnostically relevant behavior obtained over the course of that year. Results from hierarchical linear modeling analyses showed significant discriminative relationships between results from the DISC and the independent observations. Specifically, observations of symptomatic behaviors (CD or ODD) decreased for youth who met diagnostic criteria at the first administration of the DISC but not at the second, increased for youth who did not meet criteria at the first administration but did at the second, and did not change for youth who met criteria at both administrations. These results extend the data on the validity of the DISC and support continued research efforts to determine its clinical utility. 相似文献
210.
Relationships between perceived stress, coping, and smoking behavior were examined both cross-sectionally and prospectively in a large sample of English adolescents recruited from secondary schools in East Sussex. Significant cross-sectional and prospective associations are reported between smoking behavior and perceived stress, “cathartic” coping, and perception of smoking as a coping resource. The hypothesis that female adolescents smoke more than do males because they perceive more stress in their lives and cope with it differently was not supported. 相似文献