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161.
随着生命科技的迅猛发展,人类社会面临着前所未有的风险,已有的伦理学理论已不能时当代生命科技发展带来的问题给出满意的回答,生命伦理亟须理论创新.以敬畏生命为基本伦理观念,从人类的共同利益出发,在达成差异共识的基础上,构建当代生命伦理共同体,是解决当代生命科技发展带来的一系列新问题、构建和谐社会的可能路径之一. 相似文献
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163.
Wang YJ Lu J Wu DM Zheng ZH Zheng YL Wang XH Ruan J Sun X Shan Q Zhang ZF 《Neurobiology of learning and memory》2011,96(2):156-165
Evidence indicates that systemic administration of lipopolysaccharide (LPS) induces brain inflammation, ultimately resulting in cognitive deficits. Ursolic acid (UA), a plant-derived pentacyclic triterpenoid, is well known to possess multiple biological functions, including antioxidant, anti-tumor and anti-inflammatory activities. In the present study, we assessed the protective effect of UA against the LPS-induced cognitive deficits in mice. We found that UA significantly improved cognitive deficits of LPS-treated mice in open field, step-through passive avoidance and Morris water maze tasks. One potential mechanism of this action was attributed to the decreased production of pro-inflammatory markers including COX-2, iNOS, TNF-α, IL-1β, IL-2 and IL-6 in LPS-treated mouse brain. Mechanistically, UA markedly inhibited LPS-induced IκBα phosphorylation and degradation, NF-κB p65 nuclear translocation and p38 activation in mouse brain, but did not affect the activation of TLR4, MyD88, ERK, JNK and Akt. Taken together, these results suggest that UA may be useful for mitigating inflammation-associated brain disorders by inhibiting pro-inflammatory factors production, at least in part, through blocking the p38/NF-κB signaling pathways. 相似文献
164.
团队后援行为指成员间的作业互助行为,使团队能动态地调整分配资源和能力,从而提高团队绩效。文章首先介绍后援与组织公民行为、关系绩效等概念的异同。然后介绍影响后援行为的三大类因素:个体因素、团队因素、组织因素。再介绍后援行为的两种测量方法:非判断性测量和判断性测量法。最后对今后的研究提出几点启示。 相似文献
165.
中国管理心理学发展的回顾和展望 总被引:2,自引:0,他引:2
本文以 1 980年中国心理学会工业心理学专业委员会成立为标志 ,总结了 1 5年来我国工业心理学的主要成就 ,并从激励、人员测评、领导行为、管理决策和跨文化研究等方面概述了中国管理心理学的发展 ,提出了今后值得研究的若干课题。本文最后指出 ,从我国企业的实际问题着手 ,不断积累资料 ,提出自己的理论 ,同时以我为主 ,借鉴国外的研究成果 ,在企业实际中不断检验和修正理论 ,是我国管理心理学的发展方向。 相似文献
166.
Oi-ling Siu Chang-qin Lu Paul E. Spector 《European Journal of Work and Organizational Psychology》2013,22(5):520-531
This study examined the direct relationship between two social stressors (interpersonal conflict and organizational politics) and supervisor-rated job performance among employees in three Chinese societies in Greater China. The potential moderating effects of social support on the relation between social stressors and job performance were also investigated. Further, the potential mediating role of strain between stressors and job performance was tested. Data were collected from 1032 employees in Beijing, Hong Kong, and Taipei. The results showed that both types of social stressors were positively correlated with strain, and negatively related with job performance. There was evidence supporting that social support was a significant moderator of the social stressor–performance relationship. Further, results were consistent with the hypothesis that strain could be a mediator between social stressors and job performance. 相似文献
167.
Suicide method used by adolescents was examined to determine if it was the same as that employed by their suicidal parents. Six hundred eighty adolescents completed suicide between 1997 and 2007, of whom 12 had parents who had previously died by suicide. The suicide method used by these adolescents was compared with that employed by their suicidal parent and that of a matched peer control adolescent with no exposure to parental suicide and living in the same area. In 10 of the 12 suicidal parent-adolescent dyads, the same suicide method was employed by parent and adolescent. Of seven adolescents whose age at parental suicide was 15 years or above, six used the same suicide method as their suicidal parent had. On the contrary, of 12 exposure-nonexposure suicidal adolescent dyads, the same method was used in only four. Adolescents exposed to parental suicide are more likely to use the suicide method employed by their suicidal parents than the method used by adolescent peers with no exposure to parental suicide. 相似文献
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169.
Noise exclusion in spatial attention 总被引:5,自引:0,他引:5
Precue validity affects the performance of perceptual tasks. These spatial attention effects have been variously attributed to facilitation of processing, capacity allocation, or noise reduction. We used a new attention-plus-external (stimulus)-noise paradigm and model to identify the mechanisms of attention in cue-validity paradigms. A new phenomenon is reported: a large effect of location cue validity in an orientation identification task that specifically occurs when the stimulus is embedded in external (environmental or stimulus) noise. This result identifies the mechanism of the effect as external-noise exclusion, distinguished from stimulus enhancement that manifests itself only in noiseless stimulus environments. 相似文献
170.
The glare effect is an illusion in which a region appears self-luminous when flanked by gradients that decrease in luminance with distance from the region (Zavagno, 1999 Perception 28 835-838). This region also appears brighter than a surface of the same luminance. We investigated, using the paradigm of afterimages, whether a low-level mechanism at the level of the retina or LGN could account for this apparent brighter sensation. We first replicated the result from the literature that brighter and longer-lasting physical stimuli generate longer-lasting afterimages. We then compared the glare-effect stimuli with their counterpart controls, and found that the glare-effect stimuli did not give rise to longer-lasting afterimages. This suggests that the apparent brighter sensation of the glare effect is not due to a retinal or LGN mechanism, but must have a cortical origin. 相似文献